Search Results - "Hettinga, Angela"

Blimp-1 expressing lung ILC2s are a distinct cell population in allergic asthma by Zhang, Jinyi, He, Kun, Ford, B. Rhodes, Hettinga, Angela, Poholek, Amanda C.

“…Blimp-1 is a transcription factor known to have critical roles in multiple cell types including B, T and NK cells. However, its expression and function in…”
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Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung by He, Kun, Hettinga, Angela, Kale, Sagar Laxman, Hu, Sanmei, Xie, Markus M, Dent, Alexander L, Ray, Anuradha, Poholek, Amanda C

“…A Th2 immune response is central to allergic airway inflammation, which afflicts millions worldwide. However, the mechanisms that augment GATA3 expression in…”
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The transcriptional repressor Blimp-1 promotes Th2 development and lung inflammatory disease in a house dust mite induced model of allergic asthma by Poholek, Amanda C, Hettinga, Angela, He, Kun, Kale, Sagar, Schmitz, Elizabeth, Pandya, Shivani, Xie, Markus Ming, Dent, Alexander, Oriss, Timothy B, Ray, Anuradha

“…Asthma is a T cell-mediated chronic inflammatory lung disease that is thought of as a type 2/Th2 disease, yet precisely how Th2 cell development in the lung is…”
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