Search Results - "Hetland, R B"

Particulate matter properties and health effects: consistency of epidemiological and toxicological studies by Schwarze, P E, Ovrevik, J, Låg, M, Refsnes, M, Nafstad, P, Hetland, R B, Dybing, E

“…Identifying the ambient particulate matter (PM) fractions or constituents, critically involved in eliciting adverse health effects, is crucial to the…”
Get more information

Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions by Hetland, R.B, Cassee, F.R, Refsnes, M, Schwarze, P.E, Låg, M, Boere, A.J.F, Dybing, E

“…Several studies have shown that particles of smaller size may be more potent than larger to induce inflammatory and toxic responses in cultured lung cells…”
Get full text

Iron release and ROS generation from mineral particles are not related to cytokine release or apoptosis in exposed A549 cells by Øvrevik, J., Hetland, R.B., Schins, R.P., Myran, T., Schwarze, P.E.

“…The generation of reactive oxygen species (ROS) by mineral particles is believed to be central to their toxicity and their ability to induce inflammation…”
Get full text

Importance of soluble metals and reactive oxygen species for cytokine release induced by mineral particles by Hetland, R.B, Myhre, O, Låg, M, Hongve, D, Schwarze, P.E, Refsnes, M

“…The mechanisms for particle-induced health effects are not well understood, but inflammation seems to be of importance. Previously, we have shown that stone…”
Get full text

Silica-induced cytokine release from A549 cells: importance of surface area versus size by Hetland, R B, Schwarze, P E, Johansen, B V, Myran, T, Uthus, N, Refsnes, M

“…Physical and chemical properties such as structure, composition and surface reactivity determine the biological activity of mineral particles. Long-term…”
Get more information

Importance of Size and Composition of Particles for Effects on Cells In Vitro by Schwarze, P. E., Øvrevik, J., Hetland, R. B., Becher, R., Cassee, F. R., Låg, M., Løvik, M., Dybing, E., Refsnes, M.

“…A primary goal of current research on particle-induced health effects is to reveal the critical characteristics that determine their biological effects…”
Get full text

Mineral Particles of Varying Composition Induce Differential Chemokine Release from Epithelial Lung Cells: Importance of Physico-chemical Characteristics by ØVREVIK, J., MYRAN, T., REFSNES, M., LÅG, M., BECHER, R., HETLAND, R. B., SCHWARZE, P. E.

“…Presently, little is known about the potential health effects of mineral particles other than asbestos and quartz. In this study, a human epithelial lung cell…”
Get full text

Role of signal transduction pathways in lung inflammatory responses by Schwarze, P.E, Låg, M, Becher, R, Thrane, E.V, Samuelsen, J.T, Hetland, R.B, Refsnes, M

“…A variety of cell types participate in lung inflammation. Macrophages and epithelial cells play an important role in the inflammatory process by releasing…”
Get full text

Relation Between Sources of Particulate Air Pollution and Biological Effect Parameters in Samples from Four European Cities: An Exploratory Study by Steerenberg, Peter A., van Amelsvoort, Ludo, Lovik, Martinus, Hetland, Ragna B., Alberg, Torunn, Halatek, Tadeusz, Bloemen, Henk J. T., Rydzynski, Konrad, Swaen, Gerard, Schwarze, Per, Dybing, Erik, Cassee, Flemming R.

“…Given that there are widely different prevalence rates of respiratory allergies and asthma between the countries of Europe and that exposure to ambient…”
Get full text

Respiratory allergy adjuvant and inflammatory effects of urban ambient particles by Dybing, Erik, Løvdal, Torun, Hetland, Ragna Bogen, Løvik, Martinus, Schwarze, Per E

“…PM 10 and PM 2.5 fractions were collected by high-volume cascade impactors during 4-week periods in spring, summer and winter seasons in Amsterdam, Lodz, Oslo…”
Get full text

RAT LUNG INFLAMMATORY RESPONSES AFTER IN VIVO AND IN VITRO EXPOSURE TO VARIOUS STONE PARTICLES by Becher, Rune, Hetland, Ragna B., Refsnes, Magne, Dahl, Jon E., Dahlman, Hans Jørgen, Schwarze, Per E.

Get full text

MINERAL AND/OR METAL CONTENT AS CRITICAL DETERMINANTS OF PARTICLE-INDUCED RELEASE OF IL-6 AND IL-8 FROM A549 CELLS by Hetland, R B, Refsnes, M, Myran, T, Johansen, B V, Uthus, N, Schwarze, P E

“…Mineral particles in occupational exposure and ambient air particles may cause adverse health effects in humans. In this study the ability of different stone…”
Get full text

Mineral composition other than quartz is a critical determinant of the particle inflammatory potential by SCHWARZE, Per E, HETLAND, Ragna B, REFSNES, Magne, LAG, Marit, BECHER, Rune

“…The aim of this study was to examine the inflammatory potential of stone quarry particles with differing mineral and metal composition and if the effects could…”
Get full text

Different particle determinants induce apoptosis and cytokine release in primary alveolar macrophage cultures by Refsnes, Magne, Hetland, Ragna B, Øvrevik, Johan, Sundfør, Idunn, Schwarze, Per E, Låg, Marit

“…Particles are known to induce both cytokine release (MIP-2, TNF-alpha), a reduction in cell viability and an increased apoptosis in alveolar macrophages. To…”
Get full text

RAT LUNG INFLAMMATORY RESPONSES AFTER IN VIVO AND IN VITRO EXPOSURE TO VARIOUS STONE PARTICLES by Rune Becher, Ragna B. Hetland, Magne Refsnes, Jon E. Dahl, Hans Jørgen Dahlman, Per E. Schwarze

“…Rat lung alveolar macrophages and type 2 cells were exposed for 20 h in vitro to various stone particles with differing contents of metals and minerals (a type…”
Get full text

Role of signal transduction pathways in lung inflammatory responses by SCHWARZE, P. E, LEG, M, BECHER, R, THRANE, E. V, SAMUELSEN, J. T, HETLAND, R. B, REFSNES, M

Get full text

Stone Particle-induced Interleukin-6 and -8 Release Involves Activation of MAP Kinases and Tyrosine Kinases by øVrevik, J., Låg, M., Hetland, R. B., Schwarze, P. E., Refsnes, M.

“…PM10 fractions of four different stone particles used in road pavement (mylonite, gabbro, basalt and feldspar) were shown to induce a significant increase in…”
Get full text