Search Results - "Hetherington, H"

Hippocampal correlates of pain in healthy elderly adults: A pilot study by ZIMMERMAN, M. E, PAN, J. W, HETHERINGTON, H. P, LIPTON, M. L, BAIGI, K, LIPTON, R. B

“…Few neuroimaging investigations of pain in elderly adults have focused on the hippocampus, a brain structure involved in nociceptive processing that is also…”
Get full text

Selective homonuclear polarization transfer for spectroscopic imaging of GABA at 7T by Pan, J. W., Duckrow, R. B., Spencer, D. D., Avdievich, N. I., Hetherington, H. P.

“…We develop and implement a selective homonuclear polarization transfer method for the detection of 3.0 ppm C‐4 GABA resonance by spectroscopic imaging in the…”
Get full text

Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults by KUZNIECKY, R, HO, S, PAN, J, MARTIN, R, GILLIAM, F, FAUGHT, E, HETHERINGTON, H

“…Anticonvulsant drugs have multiple mechanisms of action. Recent in vivo MRS studies suggest that cerebral gamma-aminobutyric acid (GABA) increases occur with…”
Get full text

Short echo spectroscopic imaging of the human brain at 7T using transceiver arrays by Avdievich, N.I., Pan, J.W., Baehring, J.M., Spencer, D.D., Hetherington, H.P.

“…Recent advances in magnet technology have enabled the construction of ultrahigh‐field magnets (7T and higher) that can accommodate the human head and body…”
Get full text

Review of evidence for a toxicological mechanism of idiopathic environmental intolerance by Hetherington, Lh, Battershill, Jm

“…Idiopathic environmental intolerance (IEI) is a medically unexplained disorder characterised by a wide variety of unspecific symptoms in different organ…”
Get more information

A subcortical network of dysfunction in TLE measured by magnetic resonance spectroscopy by HETHERINGTON, H. P, KUZNIECKY, R. I, VIVES, K, DEVINSKY, O, PACIA, S, LUCIANO, D, VASQUEZ, B, HAUT, S, SPENCER, D. D, PAN, J. W

“…The goal of this work was to evaluate the relationship between neuronal injury/loss in the hippocampus, thalamus, and putamen in temporal lobe epilepsy (TLE)…”
Get full text

J-refocused coherence transfer spectroscopic imaging at 7 T in human brain by Pan, J.W., Avdievich, N., Hetherington, H.P.

“…Short echo spectroscopy is commonly used to minimize signal modulation due to J‐evolution of the cerebral amino acids. However, short echo acquisitions suffer…”
Get full text

Hippocampal neurochemistry, neuromorphometry, and verbal memory in nondemented older adults by ZIMMERMAN, M. E, PAN, J. W, HETHERINGTON, H. P, KATZ, M. J, VERGHESE, J, BUSCHKE, H, DERBY, C. A, LIPTON, R. B

“…Characterization of the behavioral correlates of neuromorphometry and neurochemistry in older adults has important implications for an improved understanding…”
Get full text

Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults by MARTIN, R, KUZNIECKY, R, HO, S, HETHERINGTON, H, PAN, J, SINCLAIR, K, GILLIAM, F, FAUGHT, E

“…To study the acute and steady-state cognitive effects of three new antiepileptic drugs (AEDs): gabapentin, lamotrigine, and topiramate. Several newer…”
Get full text

Advances in imaging explosive blast mild traumatic brain injury by Hetherington, H, Bandak, A, Ling, G, Bandak, F A

“…In the past, direct physical evidence of mild traumatic brain injury (mTBI) from explosive blast has been difficult to obtain through conventional imaging…”
Get more information

Metabolic networks in epilepsy by MR spectroscopic imaging by Pan, J. W., Spencer, D. D., Kuzniecky, R., Duckrow, R. B., Hetherington, H., Spencer, S. S.

“…Objective The concept of an epileptic network has long been suggested from both animal and human studies of epilepsy. Based on the common observation that the…”
Get full text

OCCIPITAL LEVELS OF GABA ARE RELATED TO SEVERE HEADACHES IN MIGRAINE by BIGAL, M. E, HETHERINGTON, H, PAN, J, TSANG, A, GROSBERG, B, AVDIEVICH, N, FRIEDMAN, B, LIPTON, R. B

Get full text

Quantitative (31)P spectroscopic imaging of human brain at 4 Tesla: assessment of gray and white matter differences of phosphocreatine and ATP by Hetherington, H P, Spencer, D D, Vaughan, J T, Pan, J W

“…This report describes the implementation and application of a multicompartment analysis of (31)P spectroscopic imaging data to determine the tissue-specific…”
Get full text

Intracranial EEG power and metabolism in human epilepsy by Pan, J.W, Zaveri, H.P, Spencer, D.D, Hetherington, H.P, Spencer, S.S

“…Summary EEG power and high frequency activity in the seizure onset zone has been increasingly considered for its relationship with seizures in animal and human…”
Get full text

Dorsal subthalamotomy for Parkinson's disease by Alvarez, L., Macias, R., Guridi, J., Lopez, G., Alvarez, E., Maragoto, C., Teijeiro, J., Torres, A., Pavon, N., Rodriguez-Oroz, M.C., Ochoa, L., Hetherington, H., Juncos, J., DeLong, M.R., Obeso, J.A.

“…We report our experience of unilateral subthalamotomy in patients with Parkinson's disease (PD). Eleven patients were included in a pilot, open‐labeled study…”
Get full text

Regional energetic dysfunction in hippocampal epilepsy by Pan, J. W., Kim, J. H., Cohen-Gadol, A., Pan, C., Spencer, D. D., Hetherington, H. P.

“…Objectives – There is increasing evidence for a dysfunctional metabolic network in human mesial temporal lobe epilepsy (MTLE). To further describe this, we…”
Get full text

Mesial temporal lobe epilepsy: a proton magnetic resonance spectroscopy study and a histopathological analysis by COHEN-GADOL, Aaron A, PAN, Jullie W, KIM, Jung H, SPENCER, Dennis D, HETHERINGTON, Hoby H

“…Proton magnetic resonance (MR) spectroscopy imaging of the ratio of N-acetylaspartate (NAA) to creatine (Cr) has proved efficacious as a localizing tool in…”
Get full text

High frequency volume coils for clinical NMR imaging and spectroscopy by Vaughan, J T, Hetherington, H P, Otu, J O, Pan, J W, Pohost, G M

“…A tuned transmission line resonator has been developed in theory and in practical design for the clinical NMR volume coil application at 4.1 tesla. The…”
Get more information

Hippocampal extracellular GABA correlates with metabolism in human epilepsy by Pan, J. W., Cavus, I., Kim, J., Hetherington, H. P., Spencer, D. D.

“…As the major inhibitory neurotransmitter in human brain, GABA is an important modulator of hyperexcitability in epilepsy patients. Given the high energetic…”
Get full text

Measurement of β‐hydroxybutyrate in acute hyperketonemia in human brain by Pan, J. W., Telang, F. W., Lee, J. H., De Graaf, R. A., Rothman, D. L., Stein, D. T., Hetherington, H. P.

“…We report the measurement of d‐β‐hydroxybutyrate (BHB) in the brains of six normal adult subjects during acute infusions of BHB. We used high field in vivo1H…”
Get full text