Search Results - "Heth, J.A"

Phase 1 TITE-CRM Dose Escalation Study of Concurrent Temozolomide and Intensity Modulated Radiation Therapy in Newly Diagnosed Glioblastoma Multiforme by Brown, D.R, Normolle, D, Junck, L.R, Lawrence, T.S, Heth, J.A, Hayman, J.A, Ten Haken, R.K, Chenevert, T, Piert, M.R, Tsien, C.I

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A Phase 0 Study Assessing the Intracranial Activity of a Metabolic Radiosensitizer in Patients with Glioblastoma by Elaimy, A.L., Al-Holou, W., Scott, A., Marini, B.L., Pai, A., Wen, B., Wang, L., Sun, D., Heth, J.A., Umemura, Y., Wahl, D.R.

“…Efforts to overcome treatment resistance in glioblastoma (GBM) have been unsuccessful due to tumor heterogeneity and poor intracranial drug penetration…”
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Identification of Excellent Prognosis IDH Wildtype Glioblastomas Using Genomic and Metabolic Profiling by Edwards, D.M., Hopkins, A., Scott, A., Mannan, R., Cao, X., Zhang, L., Andren, A., Heth, J.A., Muraszko, K., Sagher, O., Orringer, D., Hollon, T., Hervey-Jumper, S., Venneti, S., Camelo-Piragua, S., Al-Holou, W., Chinnaiyan, A., Lyssiotis, C.A., Wahl, D.R.

“…High grade gliomas (HGGs) are aggressive brain tumors with altered cellular metabolism. HGGs can carry mutations in the tricarboxylic acid (TCA) cycle enzyme…”
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