Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix

Spreading of Tissue Spheroids on an Electrospun Polyurethane Matrix

Tissue spheroids formed from fibroblasts using a micromolded non-adhesive hydrogel were located using a three-dimensional (3D) bioprinter on the surface of a nanofibrous polyurethane matrix produced by electrospinning. It was shown that the tissue spheroids attach to the matrix surface within a few...

Full description

Saved in:
Bibliographic Details
Published in:Biomedical engineering Vol. 50; no. 1; pp. 1 - 4
Main Authors: Koudan, E. V., Bulanova, E. A., Pereira, F. D. A. S., Parfenov, V. A., Kasyanov, V. A., Hesuani, U. J., Mironov, V. A.
Format: Journal Article
Language:English
Published: New York Springer US 01-05-2016
Springer
Springer Nature B.V
Subjects:
Adhesives
Biocompatibility
Bioengineering
Biomaterials
Biomedical Engineering and Bioengineering
Electrospinning
Engineering
Fibroblasts
Flattening
Organs
Polyurethane
Polyurethane resins
Polyurethanes
Spheroids
Spreading
Theory and Design
Three dimensional
Three dimensional printing
Tissue engineering
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Tissue spheroids formed from fibroblasts using a micromolded non-adhesive hydrogel were located using a three-dimensional (3D) bioprinter on the surface of a nanofibrous polyurethane matrix produced by electrospinning. It was shown that the tissue spheroids attach to the matrix surface within a few hours and completely flatten after several days, indicating high biocompatibility of the matrix used. Tissue structures formed by the attachment and spreading of tissue spheroids on an electrospun matrix are a new technological platform for biofabrication and 3D bioprinting of tissues and organs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0006-3398
1573-8256
DOI:10.1007/s10527-016-9575-5