Search Results - "Hesser, Lauren A"

Fecal microbiome and metabolome differ in healthy and food-allergic twins by Bao, Riyue, Hesser, Lauren A, He, Ziyuan, Zhou, Xiaoying, Nadeau, Kari C, Nagler, Cathryn R

“…BACKGROUNDThere has been a striking generational increase in the prevalence of food allergies. We have proposed that this increase can be explained, in part,…”
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Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food by Kemter, Andrea M., Patry, Robert T., Arnold, Jack, Hesser, Lauren A., Campbell, Evelyn, Ionescu, Edward, Mimee, Mark, Wang, Shan, Nagler, Cathryn R.

“…The increasing prevalence of food allergies has been linked to reduced commensal microbial diversity. In this article, we describe two features of…”
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Developing synbiotic bacterial therapeutics to treat food allergy by Hesser, Lauren A., Hubbell, Jeffrey A, Nagler, Cathryn

“…Abstract The recent generational rise in the incidence of food allergies has been correlated to adverse changes in the commensal microbiome, particularly…”
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B cells and the microbiota: a missing connection in food allergy by Campbell, Evelyn, Hesser, Lauren A., Nagler, Cathryn R.

“…Food allergies are a major public health concern due to their widespread and rising prevalence. The increase in food allergy is partially due to Western…”
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Optimizing bacteriotherapy to prevent or treat food allergy by Hesser, Lauren A., Hubbell, Jeffrey, Nagler, Cathryn

“…Abstract Depletion of protective gut microbes strongly correlates with the increasing prevalence of non-communicable diseases, including food allergies. In…”
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A Lipopolysaccharide-Enriched Cow's Milk Allergy Microbiome Promotes a TLR4-Dependent Proinflammatory Intestinal Immune Response by Campbell, Evelyn, Hesser, Lauren A, Berni Canani, Roberto, Carucci, Laura, Paparo, Lorella, Patry, Robert T, Nagler, Cathryn R

“…We have previously reported that the gut microbiota of healthy infants harbors allergy-protective bacteria taxa that are depleted in infants with cow's milk…”
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A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice by Hesser, Lauren A, Puente, Armando A, Arnold, Jack, Ionescu, Edward, Mirmira, Anjali, Talasani, Nidhi, Lopez, Jacqueline, Maccio-Maretto, Lisa, Mimee, Mark, Nagler, Cathryn R

“…Depletion of beneficial microbes by modern lifestyle factors correlates with the rising prevalence of food allergies. Re-introduction of allergy-protective…”
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Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles by Wang, Ruyi, Cao, Shijie, Bashir, Mohamed Elfatih H., Hesser, Lauren A., Su, Yanlin, Hong, Sung Min Choi, Thompson, Andrew, Culleen, Elliot, Sabados, Matthew, Dylla, Nicholas P., Campbell, Evelyn, Bao, Riyue, Nonnecke, Eric B., Bevins, Charles L., Wilson, D. Scott, Hubbell, Jeffrey A., Nagler, Cathryn R.

“…The microbiome modulates host immunity and aids the maintenance of tolerance in the gut, where microbial and food-derived antigens are abundant. Yet modern…”
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A wild approach to obesity prevention by Hesser, Lauren A., Nagler, Cathryn R.

“…Obesity is a growing public-health problem that has been linked to lifestyle changes affecting the diet, which in turn may lead to changes in the commensal…”
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A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice by Cao, Shijie, Budina, Erica, Raczy, Michal M., Solanki, Ani, Nguyen, Mindy, Beckman, Taryn N., Reda, Joseph W., Hultgren, Kevin, Ang, Phillip S., Slezak, Anna J., Hesser, Lauren A., Alpar, Aaron T., Refvik, Kirsten C., Shores, Lucas S., Pillai, Ishita, Wallace, Rachel P., Dhar, Arjun, Watkins, Elyse A., Hubbell, Jeffrey A.

“…Butyrate—a metabolite produced by commensal bacteria—has been extensively studied for its immunomodulatory effects on immune cells, including regulatory T…”
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A single species bacterial therapy reduces type 2 immune responses in the gut to prevent food allergy by Hesser, Lauren A., Hubbell, Jeffrey A, Nagler, Cathryn

“…Abstract The rising prevalence of food allergy is strongly correlated with dysbiosis of the gut microbiome. Rescuing this dysbiosis by reintroducing specific…”
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Developing a synbiotic biotherapy to prevent allergic responses to food by Hesser, Lauren A., Maccio-Maretto, Lisa, Hubbell, Jeffrey, Nagler, Cathryn

“…Abstract Over the past generation, the prevalence of food allergies has risen dramatically, but the development of treatments has lagged. The commensal gut…”
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The differential influence of commensal and pathogenic flagella on intestinal barrier function by Patry, Robert T, Kemter, Andrea, Mimee, Mark, Arnold, Jack, Hesser, Lauren A., Ionescu, Edward, Nagler, Cathryn

“…Abstract It is well known that accumulated changes in microbiota composition over several decades have contributed to an increase in non-communicable chronic…”
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Fecal microbiome and metabolome differ in healthy and food-allergic twins by Bao, Riyue, Hesser, Lauren A, He, Ziyuan, Zhou, Xiaoying, Nadeau, Kari C, Nagler, Cathryn R

“…BACKGROUND. There has been a striking generational increase in the prevalence of food allergies. We have proposed that this increase can be explained, in part,…”
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Flagella and indole produced by commensal bacteria protect the intestinal barrier to prevent food allergy by Kemter, Andrea Maria, Patry, Robert T., Arnold, Jack, Campbell, Evelyn, Hesser, Lauren A., Ionescu, Edward, Nagler, Cathryn

“…Abstract Lifestyle-induced changes to the diversity of the commensal microbiota have been causally linked to the increasing prevalence of food allergies and…”
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Clostridia metabolites promote intestinal barrier integrity to protect from food allergy by Kemter, Andrea Maria, Patry, Robert T., Hesser, Lauren A., Arnold, Jack, Littmann, Eric, Campbell, Evelyn, Nagler, Cathryn

“…Abstract We previously reported that a consortium of bacteria from the Clostridia class modulates intestinal barrier function through induction of IL-22 and…”
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Lymph node-targeted long-acting butyrate micelles induce regulatory immune modulation by Cao, Shijie, Wang, Ruyi, Bashir, Mohamed Elfatih H., Su, Yanlin, Sabados, Matthew, Hesser, Lauren A., Nagler, Cathryn R., Hubbell, Jeffrey A.

“…Abstract Regulatory T cells (Tregs) play essential roles in maintaining immune homeostasis and preventing autoimmunity and allergy. Peripherally derived Tregs…”
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