Search Results - "Hesseling, Anneke C"

Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa by Loxton, André G, Knaul, Julia K, Grode, Leander, Gutschmidt, Andrea, Meller, Christiane, Eisele, Bernd, Johnstone, Hilary, van der Spuy, Gian, Maertzdorf, Jeroen, Kaufmann, Stefan H E, Hesseling, Anneke C, Walzl, Gerhard, Cotton, Mark F

“…Tuberculosis is a global threat to which infants are especially vulnerable. Effective vaccines are required to protect infants from this devastating disease…”
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Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies by Garcia-Prats, Anthony J, Schaaf, H Simon, Draper, Heather R, Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C, Savic, Rada M

“…Linezolid is increasingly important for multidrug-resistant tuberculosis (MDR-TB) treatment. However, among children with MDR-TB, there are no linezolid…”
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Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons by Gupta, Amita, Hughes, Michael D, Garcia-Prats, Anthony J, McIntire, Katherine, Hesseling, Anneke C

“…Amita Gupta and colleagues discuss priorities in clinical research aimed at improving tuberculosis prevention and treatment in pregnant women, children, and…”
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Early mortality in tuberculosis patients initially lost to follow up following diagnosis in provincial hospitals and primary health care facilities in Western Cape, South Africa by Osman, Muhammad, Meehan, Sue-Ann, von Delft, Arne, Du Preez, Karen, Dunbar, Rory, Marx, Florian M, Boulle, Andrew, Welte, Alex, Naidoo, Pren, Hesseling, Anneke C

“…In South Africa, low tuberculosis (TB) treatment coverage and high TB case fatality remain important challenges. Following TB diagnosis, patients must link…”
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Pharmaceutical cost dynamics for the treatment of rifampicin-resistant tuberculosis in children and adolescents in South Africa, India, and the Philippines by Wilkinson, Thomas, Garcia-Prats, Anthony J, Sachs, Tina, Paradkar, Mandar, Suryavanshi, Nishi, Kinikar, Aarti, Frias, Melchor V, Sinanovic, Edina, Hesseling, Anneke C, Seddon, James A, Palmer, Megan

“…Rifampicin-resistant (RR) tuberculosis (TB) in children is a major global health concern but is often neglected in economics research. Accurate cost…”
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Morbidity and mortality up to 5 years post tuberculosis treatment in South Africa: A pilot study by Osman, Muhammad, Welte, Alex, Dunbar, Rory, Brown, Rosemary, Hoddinott, Graeme, Hesseling, Anneke C., Marx, Florian M.

“…•This is the first study to present data on mortality after the successful completion of tuberculosis (TB) treatment in Africa.•Mortality among successfully…”
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Tuberculosis Disease during Pregnancy and Treatment Outcomes in HIV-Infected and Uninfected Women at a Referral Hospital in Cape Town by Bekker, Adrie, Schaaf, Hendrik S, Draper, Heather R, Kriel, Magdalena, Hesseling, Anneke C

“…Tuberculosis during pregnancy and treatment outcomes are poorly defined in high prevalence tuberculosis and HIV settings. A prospective cohort study of…”
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The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis by Dheda, Keertan, Gumbo, Tawanda, Maartens, Gary, Dooley, Kelly E, Murray, Megan, Furin, Jennifer, Nardell, Edward A, Warren, Robin M, Dheda, Keertan, Gumbo, Tawanda, Maartens, Gary, Dooley, Kelly E, Esmail, Aliasgar, Murray, Megan, Furin, Jennifer, Nardell, Edward, London, Leslie, Lessem, Erica, Limberis, Jason, Theron, Grant, McNerney, Ruth, Niemann, Stefan, Dowdy, David, Van Rie, Annelies, Pasipanodya, Jotam G, Rodrigues, Camilla, Clark, Taane G, Sirgel, Frik A, Schaaf, H Simon, Chang, Kwok Chiu, Lange, Christoph, Nahid, Payam, Fourie, Bernard, Ndjeka, Norbert, Nunn, Andrew, Migliori, GB, Udwadia, Zarir F, Horsburgh, C Robert, Churchyard, Gavin J, Menzies, Dick, Hesseling, Anneke C, Seddon, James A, Low, Marcus, Keshavjee, Salmaan, Nuermberger, Eric, McIlleron, Helen, Fennelly, Kevin P, Jindani, Amina, Jaramillo, Ernesto, Padayatchi, Nesri, Barry, Clifton E, Warren, Robin M

“…The Lancet Respiratory Medicine Commission on drug-resistant tuberculosis was published in 2017, which comprehensively reviewed and provided recommendations on…”
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Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting by Chegou, Novel N, Detjen, Anne K, Thiart, Lani, Walters, Elisabetta, Mandalakas, Anna M, Hesseling, Anneke C, Walzl, Gerhard

“…The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified…”
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Mortality during tuberculosis treatment in South Africa using an 8-year analysis of the national tuberculosis treatment register by Osman, Muhammad, van Schalkwyk, Cari, Naidoo, Pren, Seddon, James A., Dunbar, Rory, Dlamini, Sicelo S., Welte, Alex, Hesseling, Anneke C., Claassens, Mareli M.

“…In 2011, the South African HIV treatment eligibility criteria were expanded to allow all tuberculosis (TB) patients lifelong ART. The impact of this change on…”
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SARS-CoV-2 infection and pulmonary tuberculosis in children and adolescents: a case-control study by Swanepoel, Jeremi, van der Zalm, Marieke M, Preiser, Wolfgang, van Zyl, Gert, Whittaker, Elizabeth, Hesseling, Anneke C, Moore, David A J, Seddon, James A

“…The Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pandemic has had an impact on the global tuberculosis (TB) epidemic but evidence on the…”
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Paediatric tuberculosis – new advances to close persistent gaps by Marais, Ben J., Verkuijl, Sabine, Casenghi, Martina, Triasih, Rina, Hesseling, Anneke C., Mandalakas, Anna M., Marcy, Olivier, Seddon, James A., Graham, Stephen M., Amanullah, Farhana

“…•Children are over-represented among TB deaths; most dying without accessing TB care.•Major gaps persist in TB preventive treatment (TPT) provision and TB case…”
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Health system determinants of tuberculosis mortality in South Africa: a causal loop model by Osman, Muhammad, Karat, Aaron S, Khan, Munira, Meehan, Sue-Ann, von Delft, Arne, Brey, Zameer, Charalambous, Salome, Hesseling, Anneke C, Naidoo, Pren, Loveday, Marian

“…Tuberculosis (TB) is a major public health concern in South Africa and TB-related mortality remains unacceptably high. Numerous clinical studies have examined…”
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Practical and psychosocial challenges faced by caregivers influence the acceptability of multidrug-resistant tuberculosis preventive therapy for young children by Wademan, Dillon T, Hoddinott, Graeme, Purchase, Susan E, Seddon, James A, Hesseling, Anneke C, Garcia-Prats, Anthony J, Reis, Ria, Reynolds, Lindsey J

“…Drug-resistant (DR) strains of Mycobacterium tuberculosis (M. tb) are increasingly recognised as a threat to global tuberculosis (TB) control efforts…”
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Improving child tuberculosis contact identification and screening in Lesotho: Results from a mixed-methods cluster-randomized implementation science study by Hirsch-Moverman, Yael, Howard, Andrea A, Mantell, Joanne E, Lebelo, Limakatso, Frederix, Koen, Wills, Aprielle, Hesseling, Anneke C, Nachman, Sharon, Maama, Llang B, El-Sadr, Wafaa M

“…Child tuberculosis (TB) contact management is recommended for preventing TB in children but its implementation is suboptimal in high TB/HIV-burden settings…”
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Association between clinical and environmental factors and the gut microbiota profiles in young South African children by Nel Van Zyl, Kristien, Whitelaw, Andrew C., Hesseling, Anneke C., Seddon, James A., Demers, Anne-Marie, Newton-Foot, Mae

“…Differences in the microbiota in populations over age and geographical locations complicate cross-study comparisons, and it is therefore essential to describe…”
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Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations by Bekken, Gry Klouman, Ritz, Christian, Selvam, Sumithra, Jesuraj, Nelson, Hesseling, Anneke C, Doherty, T Mark, Grewal, Harleen M S, Vaz, Mario, Jenum, Synne

“…The goal of tuberculosis elimination put forward in the End TB Strategy prioritizes diagnosis and treatment of incipient and subclinical TB, recently defined…”
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Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP) by Seddon, James A, Garcia-Prats, Anthony J, Purchase, Susan E, Osman, Muhammad, Demers, Anne-Marie, Hoddinott, Graeme, Crook, Angela M, Owen-Powell, Ellen, Thomason, Margaret J, Turkova, Anna, Gibb, Diana M, Fairlie, Lee, Martinson, Neil, Schaaf, H Simon, Hesseling, Anneke C

“…Multidrug-resistant (MDR) tuberculosis (TB) presents a challenge for global TB control. Treating individuals with MDR-TB infection to prevent progression to…”
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Provider attitudes about childhood tuberculosis prevention in Lesotho: a qualitative study by Hirsch-Moverman, Yael, Mantell, Joanne E, Lebelo, Limakatso, Howard, Andrea A, Hesseling, Anneke C, Nachman, Sharon, Frederix, Koen, Maama, Llang Bridget, El-Sadr, Wafaa M

“…The World Health Organization estimated that 1.12 million children developed tuberculosis (TB) in 2018, and at least 200,000 children died from TB…”
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Association between tuberculosis and pregnancy outcomes: a retrospective cohort study of women in Cape Town, South Africa by Meehan, Sue-Ann, Hesseling, Anneke C, von Delft, Arne, Marx, Florian M, Hughes, Jennifer A, Bock, Peter, Banke-Thomas, Aduragbemi, Dunbar, Rory, Phelanyane, Florence, Smith, Mariette, Osman, Muhammad

“…BackgroundTuberculosis (TB) remains a leading cause of mortality among women of childbearing age and a significant contributor to maternal mortality. Pregnant…”
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