Search Results - "Hesse, Lars"

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  1. 1

    In Vitro Activity of LK-157, a Novel Tricyclic Carbapenem As Broad-Spectrum β-Lactamase Inhibitor by PAUKNER, Susanne, HESSE, Lars, PREGELJ, Andrej, SOLMAJER, Tomaz, URLEB, Uros

    Published in Antimicrobial Agents and Chemotherapy (01-02-2009)
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    Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease by Scheuermann, Stefan, Hambsch, Boris, Hesse, Lars, Stumm, Joachim, Schmidt, Carsten, Beher, Dirk, Bayer, Thomas A., Beyreuther, Konrad, Multhaup, Gerd

    Published in The Journal of biological chemistry (07-09-2001)
    “…We reported previously that the carbohydrate domain of the amyloid precursor protein is involved in amyloid precursor protein (APP)-APP interactions…”
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    The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I) by Multhaup, Gerd, Schlicksupp, Andrea, Hesse, Lars, Beher, Dirk, Ruppert, Thomas, Masters, Colin L., Beyreuther, Konrad

    “…The transition metal ion copper(II) has a critical role in chronic neurologic diseases. The amyloid precursor protein (APP) of Alzheimer's disease or a…”
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  4. 4

    Functional and Biochemical Analysis of Chlamydia trachomatis MurC, an Enzyme Displaying UDP-N-Acetylmuramate:Amino Acid Ligase Activity by Hesse, Lars, Bostock, Julieanne, Dementin, Sebastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Chopra, Ian

    Published in Journal of Bacteriology (01-11-2003)
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  5. 5

    Regulation of Amyloid Protein Precursor (APP) Binding to Collagen and Mapping of the Binding Sites on APP and Collagen Type I (∗) by Beher, Dirk, Hesse, Lars, Masters, Colin L., Multhaup, Gerd

    Published in The Journal of biological chemistry (19-01-1996)
    “…The specific binding of the amyloid precursor protein (APP) to extracellular matrix molecules suggests that APP regulates cell interactions and has a function…”
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    In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor by Paukner, Susanne, Hesse, Lars, Prezelj, Andrej, Solmajer, Tomaz, Urleb, Uros

    Published in Antimicrobial agents and chemotherapy (01-02-2009)
    “…LK-157 is a novel tricyclic carbapenem with potent activity against class A and class C beta-lactamases. When tested against the purified TEM-1 and SHV-1…”
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  7. 7

    Reactive oxygen species and Alzheimer's disease by Multhaup, Gerd, Ruppert, Thomas, Schlicksupp, Andrea, Hesse, Lars, Beher, Dirk, Masters, Colin L., Beyreuther, Konrad

    Published in Biochemical pharmacology (01-09-1997)
    “…Although a consensus that Alzheimer's disease (AD) is a single disease has not been reached yet, the involvement of the amyloid precursor protein (APP) and βA4…”
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    Copper-Binding Amyloid Precursor Protein Undergoes a Site-Specific Fragmentation in the Reduction of Hydrogen Peroxide by Multhaup, Gerd, Ruppert, Thomas, Schlicksupp, Andrea, Hesse, Lars, Bill, Eckhard, Pipkorn, Rüdiger, Masters, Colin L, Beyreuther, Konrad

    Published in Biochemistry (Easton) (19-05-1998)
    “…The extracellular domain of transmembrane Aβ amyloid precursor protein (APP) has a Cu(II) reducing activity upon Cu(II) binding associated with the formation…”
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  10. 10

    The βA4 amyloid precursor protein binding to copper by Hesse, Lars, Beher, Dirk, Masters, Colin L., Multhaup, Gerd

    Published in FEBS letters (25-07-1994)
    “…Previously it has been shown that the extracellular domain of transmembrane βA4 amyloid precursor protein (APP) includes binding sites for zine(II) and for…”
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  11. 11

    Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer's Amyloid-beta Toxicity and Oxidative Stress by White, Anthony R, Zheng, Hui, Galatis, Denise, Maher, Fran, Hesse, Lars, Multhaup, Gerd, Beyreuther, Konrad, Masters, Colin L, Cappai, Roberto

    Published in The Journal of neuroscience (15-08-1998)
    “…Studies on the amyloid precursor protein (APP) have suggested that it may be neuroprotective against amyloid-beta (Abeta) toxicity and oxidative stress…”
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  12. 12

    Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme mur D by Horton, James R., Bostock, Julieanne M., Chopra, Ian, Hesse, Lars, Phillips, Simon E.V., Adams, David J., Johnson, A.Peter, Fishwick, Colin W.G.

    Published in Bioorganic & medicinal chemistry letters (05-05-2003)
    “…Computer-based molecular design has been used to produce a series of new macrocyclic systems targeted against the bacterial cell wall biosynthetic enzyme MurD…”
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  13. 13

    Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein by Parker, Michael W, Rossjohn, Jamie, Cappai, Roberto, Feil, Susanne C, Henry, Anna, McKinstry, William J, Galatis, Denise, Hesse, Lars, Multhaup, Gerd, Beyreuther, Konrad, Masters, Colin L

    Published in Nature structural biology (01-04-1999)
    “…Amyloid precursor protein (APP) plays a central role in Alzheimer disease. A proteolytic-breakdown product of APP, called beta-amyloid, is a major component of…”
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  14. 14

    Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD by Horton, James R, Bostock, Julieanne M, Chopra, Ian, Hesse, Lars, Phillips, Simon E V, Adams, David J, Johnson, A Peter, Fishwick, Colin W G

    Published in Bioorganic & medicinal chemistry letters (05-05-2003)
    “…Computer-based molecular design has been used to produce a series of new macrocyclic systems targeted against the bacterial cell wall biosynthetic enzyme MurD…”
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    Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein by Henry, Anna, LI, Qiao‐Xin, Galatis, Denise, Hesse, Lars, Multhaup, Gerd, Beyreuther, Konrad, Masters, Colin L., Cappai, Roberto

    Published in British journal of haematology (01-11-1998)
    “…The amyloid precursor protein (APP) of Alzheimer's disease is abundantly expressed in the platelet α‐granule where its role remains unclear. This study…”
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    Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity by Al-Owais, Moza M.A., Hesse, Lars, Talbot, Simon J., Adams, David J.

    Published in Cancer letters (25-02-2002)
    “…Our demonstration of a 19 kDa anti-Kaposi's sarcoma (KS) ribonuclease (RNase) in urine from a non-pregnant female may provide at least part of the explanation…”
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  19. 19

    The amyloid precursor protein of Alzheimer's disease in the reduction of copper by Multhaup, Gerd, Schlicksupp, Andrea, Hesse, Lars, Beher, Dirk, Ruppert, Thomas, Masters, Colin L, Beyreuther, Konrad

    “…The transition metal ion copper(II) has a critical role in chronic neurologic diseases. The amyloid precursor protein @APP@ of Ahkimer,s disease or a synthetic…”
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    Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid by Paliga, K, Peraus, G, Kreger, S, Dürrwang, U, Hesse, L, Multhaup, G, Masters, C L, Beyreuther, K, Weidemann, A

    Published in European journal of biochemistry (01-12-1997)
    “…Amyloid precursor-like protein 1 (APLP1) represents an integral membrane type 1 protein of unknown function which was originally cloned from a mouse cDNA…”
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