Search Results - "Hesse, Lars"
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In Vitro Activity of LK-157, a Novel Tricyclic Carbapenem As Broad-Spectrum β-Lactamase Inhibitor
Published in Antimicrobial Agents and Chemotherapy (01-02-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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2
Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease
Published in The Journal of biological chemistry (07-09-2001)“…We reported previously that the carbohydrate domain of the amyloid precursor protein is involved in amyloid precursor protein (APP)-APP interactions…”
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3
The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)
Published in Science (American Association for the Advancement of Science) (08-03-1996)“…The transition metal ion copper(II) has a critical role in chronic neurologic diseases. The amyloid precursor protein (APP) of Alzheimer's disease or a…”
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4
Functional and Biochemical Analysis of Chlamydia trachomatis MurC, an Enzyme Displaying UDP-N-Acetylmuramate:Amino Acid Ligase Activity
Published in Journal of Bacteriology (01-11-2003)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Regulation of Amyloid Protein Precursor (APP) Binding to Collagen and Mapping of the Binding Sites on APP and Collagen Type I (∗)
Published in The Journal of biological chemistry (19-01-1996)“…The specific binding of the amyloid precursor protein (APP) to extracellular matrix molecules suggests that APP regulates cell interactions and has a function…”
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6
In vitro activity of LK-157, a novel tricyclic carbapenem as broad-spectrum {beta}-lactamase inhibitor
Published in Antimicrobial agents and chemotherapy (01-02-2009)“…LK-157 is a novel tricyclic carbapenem with potent activity against class A and class C beta-lactamases. When tested against the purified TEM-1 and SHV-1…”
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7
Reactive oxygen species and Alzheimer's disease
Published in Biochemical pharmacology (01-09-1997)“…Although a consensus that Alzheimer's disease (AD) is a single disease has not been reached yet, the involvement of the amyloid precursor protein (APP) and βA4…”
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4-Substituted Trinems as Broad Spectrum β-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity
Published in Journal of medicinal chemistry (23-08-2007)“…A wide variety of pathogens have acquired antimicrobial resistance as an inevitable evolutionary response to the extensive use of antibacterial agents. In…”
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9
Copper-Binding Amyloid Precursor Protein Undergoes a Site-Specific Fragmentation in the Reduction of Hydrogen Peroxide
Published in Biochemistry (Easton) (19-05-1998)“…The extracellular domain of transmembrane Aβ amyloid precursor protein (APP) has a Cu(II) reducing activity upon Cu(II) binding associated with the formation…”
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The βA4 amyloid precursor protein binding to copper
Published in FEBS letters (25-07-1994)“…Previously it has been shown that the extracellular domain of transmembrane βA4 amyloid precursor protein (APP) includes binding sites for zine(II) and for…”
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Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer's Amyloid-beta Toxicity and Oxidative Stress
Published in The Journal of neuroscience (15-08-1998)“…Studies on the amyloid precursor protein (APP) have suggested that it may be neuroprotective against amyloid-beta (Abeta) toxicity and oxidative stress…”
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12
Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme mur D
Published in Bioorganic & medicinal chemistry letters (05-05-2003)“…Computer-based molecular design has been used to produce a series of new macrocyclic systems targeted against the bacterial cell wall biosynthetic enzyme MurD…”
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13
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
Published in Nature structural biology (01-04-1999)“…Amyloid precursor protein (APP) plays a central role in Alzheimer disease. A proteolytic-breakdown product of APP, called beta-amyloid, is a major component of…”
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14
Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD
Published in Bioorganic & medicinal chemistry letters (05-05-2003)“…Computer-based molecular design has been used to produce a series of new macrocyclic systems targeted against the bacterial cell wall biosynthetic enzyme MurD…”
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15
Rear Axle Layout for the Speede Research Vehicle
Published in ATZ worldwide (01-07-2012)Get full text
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16
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein
Published in British journal of haematology (01-11-1998)“…The amyloid precursor protein (APP) of Alzheimer's disease is abundantly expressed in the platelet α‐granule where its role remains unclear. This study…”
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Single Wheel Steering for the Research Vehicle Speed E
Published in ATZ worldwide (01-10-2013)Get full text
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18
Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity
Published in Cancer letters (25-02-2002)“…Our demonstration of a 19 kDa anti-Kaposi's sarcoma (KS) ribonuclease (RNase) in urine from a non-pregnant female may provide at least part of the explanation…”
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19
The amyloid precursor protein of Alzheimer's disease in the reduction of copper
Published in Science (American Association for the Advancement of Science) (08-03-1996)“…The transition metal ion copper(II) has a critical role in chronic neurologic diseases. The amyloid precursor protein @APP@ of Ahkimer,s disease or a synthetic…”
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20
Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid
Published in European journal of biochemistry (01-12-1997)“…Amyloid precursor-like protein 1 (APLP1) represents an integral membrane type 1 protein of unknown function which was originally cloned from a mouse cDNA…”
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