Search Results - "Hess, Martin E"
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AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue
Published in Cell (24-03-2016)“…Activation of Agouti-related peptide (AgRP) neurons potently promotes feeding, and chronically altering their activity also affects peripheral…”
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2
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
Published in Nature neuroscience (01-08-2013)“…Previous studies have shown genome-wide associations between polymorphisms in the gene FTO (fat mass and obesity associated) and type 2 diabetes and obesity,…”
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3
Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation
Published in Cell (15-11-2018)“…Adaptation of liver to the postprandial state requires coordinated regulation of protein synthesis and folding aligned with changes in lipid metabolism. Here…”
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4
The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons
Published in Cell reports (Cambridge) (11-06-2019)“…Variations in the human FTO gene have been linked to obesity and altered connectivity of the dopaminergic neurocircuitry. Here, we report that fat mass and…”
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N 6 -Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
Published in Molecular cell (15-02-2018)“…The integrated stress response (ISR) facilitates cellular adaptation to stress conditions via the common target eIF2α. During ISR, the selective translation of…”
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6
The fat mass and obesity-associated (FTO) gene: Obesity and beyond?
Published in Biochimica et biophysica acta. Molecular basis of disease (01-10-2014)“…Genome wide association studies undoubtedly linked variants of the fat mass and obesity-associated protein (FTO) to obesity. To date, however, knowledge on the…”
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7
A link between FTO, ghrelin, and impaired brain food-cue responsivity
Published in The Journal of clinical investigation (01-08-2013)“…Polymorphisms in the fat mass and obesity-associated gene (FTO) are associated with human obesity and obesity-prone behaviors, including increased food intake…”
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8
Descending octopaminergic neurons modulate sensory-evoked activity of thoracic motor neurons in stick insects
Published in Journal of neurophysiology (01-12-2019)“…Neuromodulatory neurons located in the brain can influence activity in locomotor networks residing in the spinal cord or ventral nerve cords of invertebrates…”
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An Obesity-Predisposing Variant of the FTO Gene Regulates D2R-Dependent Reward Learning
Published in The Journal of neuroscience (09-09-2015)“…Variations in the fat mass and obesity-associated (FTO) gene are linked to obesity. However, the underlying neurobiological mechanisms by which these genetic…”
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10
FTO gene variant modulates the neural correlates of visual food perception
Published in NeuroImage (Orlando, Fla.) (01-03-2016)“…Variations in the fat mass and obesity associated (FTO) gene are currently the strongest known genetic factor predisposing humans to non-monogenic obesity…”
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11
N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response
Published in Molecular cell (15-02-2018)“…The integrated stress response (ISR) facilitates cellular adaptation to stress conditions via the common target eIF2α. During ISR, the selective translation of…”
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12
Obesity: The need to eat--overruling the homeostatic control of feeding
Published in Nature reviews. Endocrinology (2014)Get full text
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13
The need to eat—overruling the homeostatic control of feeding
Published in Nature reviews. Endocrinology (01-01-2014)“…Optogenetic activation of a distinct, inhibitory pathway that connects the bed nucleus of the stria terminalis with the lateral hypothalamus leads to voracious…”
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14
An Obesity-Predisposing Variant of the FTO Gene Regulates D2R-Dependent Reward Learning
Published in The Journal of neuroscience (09-09-2015)“…Variations in the fat mass and obesity-associated (FTO) gene are linked to obesity. However, the underlying neurobiological mechanisms by which these genetic…”
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