Search Results - "Hess, Lauren"

Effects of the Combination of Atomoxetine and Oxybutynin on OSA Endotypic Traits by Taranto-Montemurro, Luigi, Messineo, Ludovico, Azarbarzin, Ali, Vena, Daniel, Hess, Lauren B., Calianese, Nicole A., White, David P., Wellman, Andrew, Sands, Scott A.

“…We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep…”
Get full text

Phenotyping Pharyngeal Pathophysiology using Polysomnography in Patients with Obstructive Sleep Apnea by Sands, Scott A, Edwards, Bradley A, Terrill, Philip I, Taranto-Montemurro, Luigi, Azarbarzin, Ali, Marques, Melania, Hess, Lauren B, White, David P, Wellman, Andrew

“…Therapies for obstructive sleep apnea (OSA) could be administered on the basis of a patient's own phenotypic causes ("traits") if a clinically applicable…”
Get full text

Ventilatory Drive Withdrawal Rather Than Reduced Genioglossus Compensation as a Mechanism of Obstructive Sleep Apnea in REM Sleep by Messineo, Ludovico, Eckert, Danny J, Taranto-Montemurro, Luigi, Vena, Daniel, Azarbarzin, Ali, Hess, Lauren B, Calianese, Nicole, White, David P, Wellman, Andrew, Gell, Laura, Sands, Scott A

“…REM sleep is associated with reduced ventilation and greater obstructive sleep apnea (OSA) severity than non-REM (nREM) sleep for reasons that have not been…”
Get full text

Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy by Sands, Scott A, Edwards, Bradley A, Terrill, Philip I, Butler, James P, Owens, Robert L, Taranto-Montemurro, Luigi, Azarbarzin, Ali, Marques, Melania, Hess, Lauren B, Smales, Erik T, de Melo, Camila M, White, David P, Malhotra, Atul, Wellman, Andrew

“…A possible precision-medicine approach to treating obstructive sleep apnoea (OSA) involves targeting ventilatory instability (elevated loop gain) using…”
Get full text

Neural ventilatory drive decline as a predominant mechanism of obstructive sleep apnoea events by Gell, Laura K, Vena, Daniel, Alex, Raichel M, Azarbarzin, Ali, Calianese, Nicole, Hess, Lauren B, Taranto-Montemurro, Luigi, White, David P, Wellman, Andrew, Sands, Scott A

“…In the classic model of obstructive sleep apnoea (OSA), respiratory events occur with sleep-related dilator muscle hypotonia, precipitating increased neural…”
Get more information

Improving clinician agreement and comfort through the development of a pediatric behavioral health huddle tool by Sanders, Nicole, Abela, Karla M., Davenport, Lisa, Lawrence, Julia, Gibbs, Karen, Hess, Lauren M.

“…Hospitalized pediatric patients with behavioral health (BH) diagnoses awaiting transfer can exhibit behaviors that may lead to workplace violence such as…”
Get full text

Predicting sleep apnea responses to oral appliance therapy using polysomnographic airflow by Vena, Daniel, Azarbarzin, Ali, Marques, Melania, Op de Beeck, Sara, Vanderveken, Olivier M, Edwards, Bradley A, Calianese, Nicole, Hess, Lauren B, Radmand, Reza, Hamilton, Garun S, Joosten, Simon A, Taranto-Montemurro, Luigi, Kim, Sang-Wook, Verbraecken, Johan, Braem, Marc, White, David P, Sands, Scott A, Wellman, Andrew

“…Abstract Study Objectives Oral appliance therapy is an increasingly common option for treating obstructive sleep apnea (OSA) in patients who are intolerant to…”
Get full text

Structure and severity of pharyngeal obstruction determine oral appliance efficacy in sleep apnoea by Marques, Melania, Genta, Pedro R., Azarbarzin, Ali, Taranto‐Montemurro, Luigi, Messineo, Ludovico, Hess, Lauren B., Demko, Gail, White, David P., Sands, Scott A., Wellman, Andrew

“…Key points •Some patients with obstructive sleep apnoea (OSA) respond well to oral appliance therapy, whereas others do not for reasons that are unclear. •In…”
Get full text

Drive versus Pressure Contributions to Genioglossus Activity in Obstructive Sleep Apnea by Gell, Laura K, Vena, Daniel, Grace, Kevin, Azarbarzin, Ali, Messineo, Ludovico, Hess, Lauren B, Calianese, Nicole, Labarca, Gonzalo, Taranto-Montemurro, Luigi, White, David P, Wellman, Andrew, Sands, Scott A

“…Loss of pharyngeal dilator muscle activity is a key determinant of respiratory events in obstructive sleep apnea (OSA). After the withdrawal of wakefulness…”
Get full text

Frequency of flow limitation using airflow shape by Mann, Dwayne L, Georgeson, Thomas, Landry, Shane A, Edwards, Bradley A, Azarbarzin, Ali, Vena, Daniel, Hess, Lauren B, Wellman, Andrew, Redline, Susan, Sands, Scott A, Terrill, Philip I

“…Abstract Study Objectives The presence of flow limitation during sleep is associated with adverse health consequences independent of obstructive sleep apnea…”
Get full text

Clinical polysomnographic methods for estimating pharyngeal collapsibility in obstructive sleep apnea by Vena, Daniel, Taranto-Montemurro, Luigi, Azarbarzin, Ali, Op de Beeck, Sara, Marques, Melania, Vanderveken, Olivier M, Edwards, Bradley A, Gell, Laura, Calianese, Nicole, Hess, Lauren B, Radmand, Reza, Hamilton, Garun S, Joosten, Simon A, Verbraecken, Johan, Braem, Marc, White, David P, Redline, Susan, Sands, Scott A, Wellman, Andrew

“…Abstract Study Objectives Obstructive sleep apnea has major health consequences but is challenging to treat. For many therapies, efficacy is determined by the…”
Get full text

A Case of Sulfhemoglobinemia Secondary to a Urinary Tract Infection by Campagna, Giovanni, Espaillat, Andre, Pfeiffer, Thomas, Powers, Jacquelyn M., McClure, Meghan, Hess, Lauren M.

“…Sulfhemoglobinemia (SulfHb) is a rare dyshemoglobinemia that can present with cyanosis in the absence of respiratory distress. It has been reported secondary…”
Get full text

Physiological mechanisms of upper airway hypotonia during REM sleep by McSharry, David G, Saboisky, Julian P, Deyoung, Pam, Jordan, Amy S, Trinder, John, Smales, Erik, Hess, Lauren, Chamberlin, Nancy L, Malhotra, Atul

“…Rapid eye movement (REM)-induced hypotonia of the major upper airway dilating muscle (genioglossus) potentially contributes to the worsening of obstructive…”
Get full text

Bilateral simultaneous presentation of Posner–Schlossman syndrome by Hess, Lauren K, Lee, Graham A, Shah, Peter

Get full text

Design, Usability, and Acceptability of a Needs-Based, Automated Dashboard to Provide Individualized Patient-Care Data to Pediatric Residents by Yarahuan, Julia K W, Lo, Huay-Ying, Bass, Lanessa, Wright, Jeff, Hess, Lauren M

“…Pediatric residency programs are required by the Accreditation Council for Graduate Medical Education to provide residents with patient-care and quality…”
Get full text

“PLEASE Complete Your Evaluations!” Strategies to Engage Faculty in Competency-Based Assessments by Hess, Lauren M., Foradori, Dana M., Singhal, Geeta, Hicks, Patricia J., Turner, Teri L.

“…Competency-based assessments (CBAs) have gained traction in graduate medical education and inform important learner outcomes through the continuum of medical…”
Get full text

Evaluation of a Sepsis Alert in the Pediatric Acute Care Setting by Gibbs, Karen DiValerio, Shi, Yan, Sanders, Nicole, Bodnar, Anthony, Brown, Terri, Shah, Mona D, Hess, Lauren M

“…Severe sepsis can cause significant morbidity and mortality in pediatric patients. Early recognition and treatment are vital to improving patient outcomes. The…”
Get full text

IV Antibiotic Durations for Nontyphoidal Salmonella Bacteremia by Hess, Lauren M, Burdick, Bethany, Minard, Charles G, Dutta, Ankhi

“…The objective was to determine if shorter intravenous (IV) antibiotic (<7 days) for nontyphoidal bacteremia (NTS-B) is noninferior to longer (≥7 days) in terms…”
Get more information

Effect of Dupilumab on Sleep Apnea Severity in Patients With Chronic Rhinosinusitis by Kim, Sang-Wook, Sands, Scott A., Vena, Daniel, Hess, Lauren B., Calianese, Nicole A., Konefal, Robert James, Taranto-Montemurro, Luigi, Azarbarzin, Ali, Czeisler, Charles A., Laidlaw, Tanya M., Wellman, Andrew

“…Patients with chronic rhinosinusitis (CRS) report improved sleep quality after dupilumab, an anti IL4/13 therapy. Concurrent CRS and obstructive sleep apnea…”
Get full text

Sitting and Supine Esophageal Pressures in Overweight and Obese Subjects by Owens, Robert L., Campana, Lisa M., Hess, Lauren, Eckert, Danny J., Loring, Stephen H., Malhotra, Atul

“…Esophageal pressure (PEs) can be used to approximate pleural pressure (Ppl) and might be clinically useful, particularly in the obese e.g., to guide mechanical…”
Get full text