Search Results - "Hess, Joshua A."

Anticancer Activity of Region B Capsaicin Analogs by Brown, Kathleen C., Modi, Kushal J., Light, Reagan S., Cox, Ashley J., Long, Timothy E., Gadepalli, Rama S., Rimoldi, John M., Miles, Sarah L., Rankin, Gary, Valentovic, Monica, Denning, Krista L., Tirona, Maria T., Finch, Paul T., Hess, Joshua A., Dasgupta, Piyali

“…The heterocyclic vanilloid compound capsaicin is responsible for the spicy and pungent flavor of chili peppers. Several convergent studies have shown that…”
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Anti-cancer activity of sustained release capsaicin formulations by Merritt, Justin C., Richbart, Stephen D., Moles, Emily G., Cox, Ashley J., Brown, Kathleen C., Miles, Sarah L., Finch, Paul T., Hess, Joshua A., Tirona, Maria T., Valentovic, Monica A., Dasgupta, Piyali

“…Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic vanilloid phytochemical abundantly found in chili peppers and pepper extracts…”
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Cancer metabolism and oxidative stress: Insights into carcinogenesis and chemotherapy via the non-dihydrofolate reductase effects of methotrexate by Hess, Joshua A, Khasawneh, Mohamad K

“…Methotrexate has been in use as an anti-cancer agent for over 60 years. Though inhibition of dihydrofolate reductase is its best known mechanisms of action,…”
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Nonpungent N‑AVAM Capsaicin Analogues and Cancer Therapy by Richbart, Stephen D, Friedman, Jamie R, Brown, Kathleen C, Gadepalli, Rama S, Miles, Sarah L, Rimoldi, John M, Rankin, Gary O, Valentovic, Monica A, Tirona, Maria T, Finch, Paul T, Hess, Joshua A, Dasgupta, Piyali

“…Capsaicin displays robust growth-inhibitory activity in multiple human cancers. However, the feasibility of capsaicin as a clinically relevant anticancer drug…”
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Case report: Childhood erythrocytosis due to hypermanganesemia caused by homozygous SLC30A10 mutation by Coppola, Tiziana, Hughes, Hannah, Finch, Paul T., Hess, Joshua A., Wu, Steve, Prada, Carlos E., Miethke, Alexander G., Zhang, Wenying, Kalfa, Theodosia A.

“…We present a rare case of erythrocytosis due to a homozygous SLC30A10 mutation, causative of Hypermanganesemia with Dystonia, Polycythemia, and Cirrhosis…”
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Spherical Invasion Assay: A Novel Method to Measure Invasion of Cancer Cells by Richbart, Stephen D, Merritt, Justin C, Moles, Emily G, Brown, Kathleen C, Adeluola, Adeoluwa A, Finch, Paul T, Hess, Joshua A, Tirona, Maria T, Miles, Sarah L, Valentovic, Monica A, Dasgupta, And Piyali

“…The invasion of tumor cells into the neighboring blood vessels and lymph nodes is a vital step for distant metastasis. Traditionally, the invasive activity of…”
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Anti-cancer activity of capsaicin and its analogs in gynecological cancers by Brown, Kathleen C, Sugrue, Amanda M, Conley, Kaitlyn B, Modi, Kushal J, Light, Reagan S, Cox, Ashley J, Bender, Christopher R, Miles, Sarah L, Denning, Krista L, Finch, Paul T, Hess, Joshua A, Tirona, Maria T, Valentovic, Monica A, Dasgupta, Piyali

“…Capsaicin is the hot and pungent ingredient of chili peppers. It is a potent pain-relieving agent and is often present in over-the-counter analgesic lotions…”
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