Search Results - "Hess, F."
-
1
Contacts between the endoplasmic reticulum and other membranes in neurons
Published in Proceedings of the National Academy of Sciences - PNAS (13-06-2017)“…Close appositions between the membrane of the endoplasmic reticulum (ER) and other intracellular membranes have important functions in cell physiology. These…”
Get full text
Journal Article -
2
Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity
Published in Cell (30-05-2019)“…Metabolic coordination between neurons and astrocytes is critical for the health of the brain. However, neuron-astrocyte coupling of lipid metabolism,…”
Get full text
Journal Article -
3
ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER
Published in Cell (29-04-2021)“…Cellular versatility depends on accurate trafficking of diverse proteins to their organellar destinations. For the secretory pathway (followed by approximately…”
Get full text
Journal Article -
4
Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER
Published in Science (American Association for the Advancement of Science) (28-10-2016)“…The endoplasmic reticulum (ER) is an expansive, membrane-enclosed organelle that plays crucial roles in numerous cellular functions. We used emerging…”
Get full text
Journal Article -
5
Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells
Published in Science (American Association for the Advancement of Science) (17-01-2020)“…Within cells, the spatial compartmentalization of thousands of distinct proteins serves a multitude of diverse biochemical needs. Correlative super-resolution…”
Get full text
Journal Article -
6
Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions
Published in Nature cell biology (01-07-2015)“…Focal adhesions (FAs) link the extracellular matrix to the actin cytoskeleton to mediate cell adhesion, migration, mechanosensing and signalling. FAs have…”
Get full text
Journal Article -
7
Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III
Published in The Journal of cell biology (05-08-2019)“…Lipid droplets (LDs) are neutral lipid storage organelles that transfer lipids to various organelles including peroxisomes. Here, we show that the hereditary…”
Get full text
Journal Article -
8
Regulation of liver subcellular architecture controls metabolic homeostasis
Published in Nature (London) (24-03-2022)“…Cells display complex intracellular organization by compartmentalization of metabolic processes into organelles, yet the resolution of these structures in the…”
Get full text
Journal Article -
9
Correlative 3D superresolution fluorescence and electron microscopy reveal the relationship of mitochondrial nucleoids to membranes
Published in Proceedings of the National Academy of Sciences - PNAS (17-04-2012)“…Microscopic images of specific proteins in their cellular context yield important insights into biological processes and cellular architecture. The advent of…”
Get full text
Journal Article -
10
Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy
Published in Angewandte Chemie International Edition (26-01-2016)“…The rhodamine system is a flexible framework for building small‐molecule fluorescent probes. Changing N‐substitution patterns and replacing the xanthene oxygen…”
Get full text
Journal Article -
11
Binocular vision in amblyopia: structure, suppression and plasticity
Published in Ophthalmic & physiological optics (01-03-2014)“…The amblyopic visual system was once considered to be structurally monocular. However, it now evident that the capacity for binocular vision is present in many…”
Get full text
Journal Article -
12
Enhanced FIB-SEM systems for large-volume 3D imaging
Published in eLife (13-05-2017)“…Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) can automatically generate 3D images with superior z-axis resolution, yielding data that needs minimal…”
Get full text
Journal Article -
13
Dichoptic training enables the adult amblyopic brain to learn
Published in Current biology (22-04-2013)“…Adults with amblyopia, a common visual cortex disorder caused primarily by binocular disruption during an early critical period, do not respond to conventional…”
Get full text
Journal Article -
14
A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility
Published in Cell (01-09-2022)“…Chemical synapses between axons and dendrites mediate neuronal intercellular communication. Here, we describe a synapse between axons and primary cilia: the…”
Get full text
Journal Article -
15
Distribution of ESCRT Machinery at HIV Assembly Sites Reveals Virus Scaffolding of ESCRT Subunits
Published in Science (American Association for the Advancement of Science) (07-02-2014)“…The human immunodeficiency virus (HIV) hijacks the endosomal sorting complexes required for transport (ESCRT) to mediate virus release from infected cells. The…”
Get full text
Journal Article -
16
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
Published in Science (American Association for the Advancement of Science) (15-09-2006)“…We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of photoactivatable fluorescent…”
Get full text
Journal Article -
17
Interocular contrast difference drives illusory 3D percept
Published in Scientific reports (17-07-2017)“…Any processing delay between the two eyes can result in illusory 3D percepts for moving objects because of either changes in the pure disparities over time for…”
Get full text
Journal Article -
18
Short-term monocular deprivation strengthens the patched eye's contribution to binocular combination
Published in Journal of vision (Charlottesville, Va.) (18-04-2013)“…Binocularity is a fundamental property of primate vision. Ocular dominance describes the perceptual weight given to the inputs from the two eyes in their…”
Get full text
Journal Article -
19
Fixation-resistant photoactivatable fluorescent proteins for CLEM
Published in Nature methods (01-03-2015)“…The fluorescent proteins mEos4a and mEos4b maintain their fluorescence and photoconversion after fixation with osmium. This property enables applications such…”
Get full text
Journal Article -
20
Superresolution Fluorescence Imaging of Mitochondrial Nucleoids Reveals Their Spatial Range, Limits, and Membrane Interaction
Published in Molecular and Cellular Biology (01-12-2011)“…OA Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
Get full text
Journal Article