Search Results - "Hess, EJ"

Migraines in Mice? by Hess, Ellen J

“…Recently, the ion channel mutations causing both familial hemiplegic migraine (FHM) and episodic ataxia type-2 (EA-2) were identified as defects in the human…”
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Loss of Locus Coeruleus Neurons and Reduced Startle in Parkin Null Mice by von Coelln, Rainer, Thomas, Bobby, Savitt, Joseph M., Lim, Kah Leong, Sasaki, Masayuki, Hess, Ellen J., Dawson, Valina L., Dawson, Ted M., Snyder, Solomon H.

“…Parkinson's disease (PD) is the most common neurodegenerative movement disorder and is characterized pathologically by degeneration of catecholaminergic…”
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Iron deficiency decreases dopamine D 1 and D 2 receptors in rat brain by Erikson, Keith M, Jones, Byron C, Hess, Ellen J, Zhang, Qian, Beard, John L

“…Iron deficiency (ID) in early life is known to alter neurological development and functioning, but data regarding specific effects on dopamine biology are…”
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Abnormal cerebellar signaling induces dystonia in mice by Pizoli, Carolyn E, Jinnah, H A, Billingsley, Melvin L, Hess, Ellen J

“…Dystonia is a relatively common neurological syndrome characterized by twisting movements or sustained abnormal postures. Although the basal ganglia have been…”
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Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy by von Coelln, Rainer, Thomas, Bobby, Andrabi, Shaida A, Lim, Kah Leong, Savitt, Joseph M, Saffary, Roya, Stirling, Wanda, Bruno, Kristy, Hess, Ellen J, Lee, Michael K, Dawson, Valina L, Dawson, Ted M

“…Mutations in the genes coding for alpha-synuclein and parkin cause autosomal-dominant and autosomal-recessive forms of Parkinson's disease (PD), respectively…”
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Potassium Channel Blockers Inhibit the Triggers of Attacks in the Calcium Channel Mouse Mutant tottering by Weisz, Catherine J. C, Raike, Robert S, Soria-Jasso, Luis E, Hess, Ellen J

“…Humans with the disorder episodic ataxia type 2 (EA2) and the tottering mouse mutant exhibit episodic attacks induced by emotional and chemical stress. Both…”
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Rodent models for dystonia research: Characteristics, evaluation, and utility by Jinnah, H.A., Hess, Ellen J., LeDoux, Mark S., Sharma, Nutan, Baxter, Mark G., DeLong, Mahlon R.

“…A large number of different genetic and acquired disorders of the nervous system may be associated with dystonia. To elucidate its pathogenesis and to…”
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Norepinephrine regulates locomotor hyperactivity in the mouse mutant coloboma by Jones, Michelle D., Hess, Ellen J.

“…An imbalance between dopaminergic and noradrenergic systems is implicated in hyperactivity disorders such as attention deficit hyperactivity disorder (ADHD)…”
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L-type calcium channels contribute to the tottering mouse dystonic episodes by Campbell, D B, Hess, E J

“…Tottering mice inherit a recessive mutation of the calcium channel alpha1A subunit that causes ataxia, polyspike discharges, and intermittent dystonic…”
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Noradrenergic blockade prevents attacks in a model of episodic dysfunction caused by a channelopathy by Fureman, Brandy E., Hess, Ellen J.

“…Episodic neurological dysfunction often results from ion channel gene mutations. Despite knowledge of the mutations, the factors that precipitate attacks in…”
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Tottering Mouse Motor Dysfunction Is Abolished on the Purkinje Cell Degeneration (pcd) Mutant Background by Campbell, Daniel B., North, Jesse B., Hess, Ellen J.

“…Tottering (tg) mice inherit a recessive mutation of the calcium channel α1A subunit gene, which encodes the pore-forming protein of P/Q-type voltage-sensitive…”
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Quantitative and Statistical Analysis of the Shape of Amperometric Spikes Recorded from Two Populations of Cells by Colliver, Thomas L., Hess, Ellen J., Pothos, Emmanuel N., Sulzer, David, Ewing, Andrew G.

“…Previously used methods of comparing amperometric spike characteristics from two separate groups of cells have entailed pooling all the values for a spike…”
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Mouse Model of Hyperkinesis Implicates SNAP-25 in Behavioral Regulation by Hess, Ellen J, Collins, Katherine A, Wilson, Michael C

“…Although hyperkinesis is expressed in several neurological disorders, the biological basis of this phenotype is unknown. The mouse mutant coloboma (Cml+)…”
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Triggers of paroxysmal dyskinesia in the calcium channel mouse mutant tottering by Fureman, Brandy E., Jinnah, H.A., Hess, Ellen J.

“…Mutations in ion channels, or channelopathies, often lead to neurological disorders in which normal behavior is interrupted by attacks of debilitating symptoms…”
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Calcium channel agonists and dystonia in the mouse by Jinnah, H. A., Sepkuty, Jehuda P., Ho, Tony, Yitta, Silaja, Drew, Touby, Rothstein, Jeffrey D., Hess, E. J.

“…Systemic administration of the L‐type calcium channel agonists ±Bay K 8644 or FPL 64176 causes a characteristic pattern of motor dysfunction in normal C57BL/6J…”
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Characterization and Distribution of Ferritin Binding Sites in the Adult Mouse Brain by Hulet, S. W., Hess, E. J., Debinski, W., Arosio, P., Bruce, K., Powers, S., Connor, J. R.

“…: Studies on iron uptake into the brain have traditionally focused on transport by transferrin. However, transferrin receptors are not found in all brain…”
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Cerebellar circuitry is activated during convulsive episodes in the tottering ( tg/ tg) mutant mouse by Campbell, D.B, Hess, E.J

“…Tottering ( tg) is an autosomal recessive mutation of the calcium channel α 1A subunit in the mouse that results in epileptic spike and wave discharges, mild…”
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Identification of the weaver Mouse Mutation: The End of the Beginning by Hess, Ellen J

“…Neurological mouse mutants have been studied for decades as models for neuronal development, pathogenesis, and neurologic disorders. Because the abnormal…”
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Sturge-Weber Syndrome: Altered Blood Vessel Fibronectin Expression and Morphology by Comi, Anne M., Weisz, Catherine J. C., Highet, Bridget H., Skolasky, Richard L., Pardo, Carlos A., Hess, Ellen J.

“…Sturge-Weber syndrome presents with vascular malformations of the brain, skin, and eye. Fibronectin has potent effects on angiogenesis, vessel remodeling, and…”
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Abnormal presynaptic catecholamine regulation in a hyperactive SNAP-25-deficient mouse mutant by Jones, M.D, Williams, M.E, Hess, E.J

“…The consequences of a reduction in the presynaptic protein, SNAP-25, were investigated to determine the neurochemical basis of the marked hyperlocomotor…”
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