Search Results - "Hesp, Anne C"
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Exposure-Response Analysis of the Sodium-Glucose Cotransporter-2 Inhibitors Dapagliflozin and Empagliflozin on Kidney Hemodynamics in Patients with Type 2 Diabetes
Published in Journal of personalized medicine (27-04-2023)“…Sodium-glucose cotransporter-2 (SGLT2) inhibitors improve markers for renal and cardiovascular outcomes in patients with and without type 2 diabetes (T2D). To…”
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Natriuretic Effect of Two Weeks of Dapagliflozin Treatment in Patients With Type 2 Diabetes and Preserved Kidney Function During Standardized Sodium Intake: Results of the DAPASALT Trial
Published in Diabetes care (01-02-2021)“…Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk for heart failure hospitalization potentially by inducing sodium excretion, osmotic diuresis,…”
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Poor Taste and Smell Are Associated with Poor Appetite, Macronutrient Intake, and Dietary Quality but Not with Undernutrition in Older Adults
Published in The Journal of nutrition (01-03-2021)“…Age-related declines in taste and smell function are widely assumed to contribute to the decrease in appetite and the development of undernutrition in older…”
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Mechanisms underlying the blood pressure‐lowering effects of empagliflozin, losartan and their combination in people with type 2 diabetes: A secondary analysis of a randomized crossover trial
Published in Diabetes, obesity & metabolism (01-01-2023)“…Aim To study the effects of the sodium‐glucose co‐transporter‐2 (SGLT2) inhibitor empagliflozin, the angiotensin receptor blocker (ARB) losartan, and their…”
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Sodium glucose cotransporter-2 inhibitors protect the cardiorenal axis: Update on recent mechanistic insights related to kidney physiology
Published in European journal of internal medicine (01-06-2022)“…•SGLT2 inhibitors are important in the treatment of type 2 diabetes, chronic kidney disease and heart failure.•SGLT2 inhibitors improve cardiovascular outcomes…”
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Kidney hemodynamic profile and systemic vascular function in adults with type 2 diabetes: Analysis of three clinical trials
Published in Journal of diabetes and its complications (01-03-2022)“…Glomerular hyperfiltration plays a key role in the pathophysiology of diabetic kidney disease (DKD). Mechanisms underlying this adverse hemodynamic profile are…”
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Skin microvascular function and renal hemodynamics in overweight patients with type 2 diabetes: A cross‐sectional study
Published in Microcirculation (New York, N.Y. 1994) (01-08-2021)“…Objective Diabetic kidney disease is a microvascular complication of diabetes. Here, we assessed the association between skin microvascular function and renal…”
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The Adaptive Renal Response for Volume Homeostasis During 2 Weeks of Dapagliflozin Treatment in People With Type 2 Diabetes and Preserved Renal Function on a Sodium-Controlled Diet
Published in Kidney international reports (01-05-2022)“…Proximal tubule sodium uptake is diminished following sodium glucose cotransporter 2 (SGLT2) inhibition. We previously showed that during SGLT2 inhibition, the…”
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