Health-related Quality of Life of Liver Donors: A Prospective Longitudinal Study

Living donor liver transplantation is a widely accepted option to treat liver diseases in several indications. Risk of liver donation is being discussed and quality of life of donors is also studied. Changes and the change pattern of quality of life were analyzed in this prospective longitudinal stu...

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Bibliographic Details
Published in:	Transplantation proceedings Vol. 50; no. 10; pp. 3076 - 3081
Main Authors:	Hesimov, I., Kirimker, E.O., Duman, B., Keskin, O., Cetinkaya, O.A., Hayme, S., Ustuner, E., Idilman, R., Yurdaydin, C., Dokmeci, A., Kumbasar, H., Yilmaz, A.A., Kologlu, M.B., Karayalcin, K., Balci, D.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-12-2018
Subjects:	Adult Female Hepatectomy - adverse effects Hepatectomy - methods Humans Liver Transplantation - methods Living Donors Longitudinal Studies Male Middle Aged Postoperative Period Prospective Studies Quality of Life Young Adult
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Summary:	Living donor liver transplantation is a widely accepted option to treat liver diseases in several indications. Risk of liver donation is being discussed and quality of life of donors is also studied. Changes and the change pattern of quality of life were analyzed in this prospective longitudinal study. Fifty-five donors were included. The Medical Outcomes Study Short Form 36 (SF-36) was fulfilled either in-person or during a telephone interview each donor preoperatively and at the end of the third, sixth, and 12th months. Physical subdomain scores of SF-36 decreased significantly in the third postoperative month compared to preoperative score. The scores recovered in the sixth postoperative month, except for the bodily pain domain. The pain score recovered at the end of the 12th month. While social functioning score among mental subdomains of SF-36 temporarily decreased and recovered at postoperative 12th month, other mental subdomain scores and mental composition summary scores did not show a significant change. The quality of life of living liver donors is not permanently affected by donation. There are well-defined changes in the physical aspects of the quality of life that all seem to recover within 1 year. Donors should be preoperatively informed about this temporary change as well as complications.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0041-1345 1873-2623
DOI:	10.1016/j.transproceed.2018.07.018