Search Results - "Heshan Kuruppu"
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Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
Published in Nature communications (29-07-2021)“…Several COVID-19 vaccines have received emergency approval. Here we assess the immunogenicity of a single dose of the AZD1222 vaccine, at one month, in a…”
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2
Immune responses following the first dose of the Sputnik V (Gam-COVID-Vac)
Published in Scientific reports (02-02-2022)“…As the first dose of Gam-COVID-Vac, is currently used as a single dose vaccine in some countries, we investigated the immunogenicity of this at 4 weeks (327…”
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3
Are viral loads in the febrile phase a predictive factor of dengue disease severity?
Published in BMC infectious diseases (05-11-2024)“…Abstract Background As many studies have shown conflicting results regarding the extent of viraemia and clinical disease severity, we sought to investigate if…”
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4
Sensitivity and specificity of two WHO approved SARS-CoV2 antigen assays in detecting patients with SARS-CoV2 infection
Published in BMC infectious diseases (22-03-2022)“…SARS-CoV-2 rapid antigen (Ag) detection kits are widely used in addition to quantitative reverse transcription PCR PCR (RT-qPCR), as they are cheaper with a…”
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5
Adipokine levels and their association with clinical disease severity in patients with dengue
Published in PLoS neglected tropical diseases (07-09-2023)“…Adipokines have not been studied in acute dengue, despite their emerging role in inducing and regulating inflammation. Therefore, we sought to identify…”
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6
Persistence of immune responses to the Sinopharm/BBIBP‐CorV vaccine
Published in Immunity, Inflammation and Disease (01-06-2022)“…Background To determine the kinetics and persistence of immune responses following the Sinopharm/BBIBP‐CorV, we investigated immune responses in a cohort of…”
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7
Molecular Epidemiology of AY.28 and AY.104 Delta Sub-lineages in Sri Lanka
Published in Frontiers in public health (21-06-2022)“…The worst SARS-CoV-2 outbreak in Sri Lanka was due to the two Sri Lankan delta sub-lineages AY.28 and AY.104. We proceeded to further characterize the…”
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Seroprevalence of SARS-CoV-2 Infection in the Colombo Municipality Region, Sri Lanka
Published in Frontiers in public health (12-11-2021)“…Background: As the Municipality Council area in Colombo (CMC) experienced the highest number of cases until the end of January 2021, in Sri Lanka, we carried…”
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Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
Published in PLOS global public health (2022)“…With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the…”
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10
Kinetics of immune responses to the AZD1222/Covishield vaccine with varying dose intervals in Sri Lankan individuals
Published in Immunity, Inflammation and Disease (01-04-2022)“…Background To understand the kinetics of immune responses with different dosing gaps of the AZD1222 vaccine, we compared antibody and T cell responses in two…”
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Antibody responses to Sinopharm/BBIBP-CorV in pregnant mothers in Sri Lanka
Published in PLOS global public health (2022)“…There are limited data regarding the safety and immunogenicity of the Sinopharm/BBIBP-CorV vaccine in pregnancy. Therefore, we sought to investigate the…”
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12
Simultaneous Cocirculation of 2 Genotypes of Dengue Virus Serotype 3 Causing a Large Outbreak in Sri Lanka in 2023
Published in The Journal of infectious diseases (15-10-2024)“…Abstract Background We observed a discrepancy between dengue NS1 antigen test and molecular diagnostics, with the emergence of dengue virus (DENV) serotype 3…”
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13
Simultaneous co-circulation of two genotypes of dengue virus serotype 3 causing a large outbreak in Sri Lanka in year 2023
Published in The Journal of infectious diseases (10-10-2024)“…We observed a discrepancy between dengue NS1 antigen test and molecular diagnostics, with the emergence of (DENV) serotype 3 in Sri Lanka and sought to…”
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14
Identification of differences in the magnitude and specificity of SARS-CoV-2 nucleocapsid antibody responses in naturally infected and vaccinated individuals
Published in Clinical and experimental immunology (19-02-2024)“…As there are limited data on B-cell epitopes for the nucleocapsid protein in SARS-CoV-2, we sought to identify the immunodominant regions within the N protein,…”
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15
Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222
Published in Clinical and experimental immunology (23-06-2022)“…To characterize the IgG and IgA responses to different SARS-CoV-2 proteins, we investigated the antibody responses to SARS-CoV-2 following natural infection…”
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16
Comparison of the Immunogenicity of five COVID-19 vaccines in Sri Lanka
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract We assessed antibody responses 3 months post-vaccination in those who received mRNA-1273 (n=225), Sputnik V (n=128) or the first dose of Gam-COVID-Vac…”
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Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka
Published in The Journal of immunology (1950) (01-12-2021)“…Abstract Due to limited access to vaccines, many countries have only administered a single dose of the AZD1222, whereas the dosage intervals have increased ≥4…”
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18
Comparison of the immunogenicity of five COVID‐19 vaccines in Sri Lanka
Published in Immunology (01-10-2022)“…To determine the antibody responses elicited by different vaccines against SARS‐CoV‐2, we compared antibody responses in individuals 3 months post‐vaccination…”
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19
Immune responses to Sinopharm/BBIBP‐CorV in individuals in Sri Lanka
Published in Immunology (01-10-2022)“…As there are limited data of the immunogenicity of the Sinopharm/BBIBP‐CorV in different populations, antibody responses against different SARS‐CoV‐2 variants…”
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20
Epidemiological and virological factors determining dengue transmission in Sri Lanka during the COVID-19 pandemic
Published in PLOS global public health (01-01-2022)“…With the onset of the COVID-19 pandemic in early 2020 there was a drastic reduction in the number of dengue cases in Sri Lanka, with an increase towards the…”
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Journal Article