Search Results - "Hesham, Dina"
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1
Epigenetic silencing of ZIC4 unveils a potential tumor suppressor role in pediatric choroid plexus carcinoma
Published in Scientific reports (12-09-2024)“…Zic family member ZIC4 is a transcription factor that has been shown to be silenced in several cancers. However, understanding the regulation and function of…”
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2
The combined role of NT-proBNP and LV-GLS in the detection of early subtle chemotherapy-induced cardiotoxicity in breast cancer female patients
Published in The Egyptian heart journal (01-03-2021)“…Background Chemotherapeutic agents have many side effects; among them is cardiotoxicity. Ejection fraction fails to detect the subtle alterations of left…”
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3
Aggresomes predict poor outcomes and implicate proteostasis in the pathogenesis of pediatric choroid plexus tumors
Published in Journal of neuro-oncology (01-03-2021)“…Purpose Protein misfolding and aggregation result in proteotoxic stress and underlie the pathogenesis of many diseases. To overcome proteotoxicity, cells…”
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4
Evaluation of the seismic response of frames implemented with metamaterials
Published in Results in engineering (01-06-2023)“…This research aims at introducing a new idea in the design of frames to eliminate or suppress the transmission of waves through the structure in a certain…”
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5
Evaluation of serum presepsin, procalcitonin, copeptin, and high-sensitivity C-reactive protein for differentiating bacterial infection from disease activity in Egyptian patients with systemic lupus erythematosus
Published in Clinical rheumatology (01-05-2021)“…Objectives Several biological markers have been studied for the differentiation of infection from disease activity in systemic lupus erythematosus (SLE)…”
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6
Comparative study of fractional CO2 laser and fractional CO2 laser-assisted drug delivery of topical steroid and topical vitamin C in macular amyloidosis
Published in Lasers in medical science (01-05-2018)“…Macular amyloidosis (MA) represents a common variant of primary localized cutaneous amyloidosis. It has a characteristic female predominance; none of the…”
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7
Sex hormone binding globulin (SHBG) as a predictor of liver fibrosis in subjects with nonalcoholic fatty liver disease (NAFLD)
Published in The Egyptian journal of internal medicine (27-05-2023)“…Background Nonalcoholic fatty liver disease (NAFLD) is the fastest growing cause of chronic liver disease worldwide. The prevalence of NAFLD increases in…”
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Urinary pigment epithelium-derived factor as a marker of diabetic nephropathy in Egyptian patients with type 2 diabetes mellitus
Published in Saudi journal of kidney diseases and transplantation (01-09-2021)“…Diabetic nephropathy (DN) is the most common cause of end-stage renal disease. Urinary pigment epithelium-derived factor (PEDF) has also been shown to suppress…”
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9
Serum Phosphorus, Parathyroid Hormone, and Serum Fibroblast Growth Factor-23 in Egyptian Patients Six Months after Undergoing Living-donor Kidney Transplantation
Published in Saudi journal of kidney diseases and transplantation (01-05-2022)“…End-stage renal disease is a major health problem with many complications. Previous studies emphasized the relationship of cardiovascular disease and mortality…”
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10
Urinary podocalyxin : is it a real index of disease activity in Egyptian patients lupus nephritis
Published in Saudi journal of kidney diseases and transplantation (01-11-2020)“…Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by production of a number of antinuclear antibodies. Podocyte injury is…”
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11
Increased arterial stiffness in rheumatoid arthritis and Its relation to disease activity: A cross sectional study
Published in The Egyptian heart journal (01-03-2018)“…Rheumatoid arthritis (RA) is associated with elevated plasma level of inflammatory markers. Chronic inflammation is known to predispose to endothelial…”
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12
Results of treatment of lymphoblastic lymphoma at the children cancer hospital Egypt – A single center experience
Published in Journal of Egyptian National Cancer Institute (01-09-2016)“…Introduction Lymphoblastic lymphoma (LBL) and acute lymphoblastic leukemia (ALL) are neoplasms of immature B or T-cell precursors. They are considered as a…”
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13
Abstract LB-220: Functional consequences of aberrant alternative splicing in embryonal tumor with multilayered rosettes
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Embryonal tumor with multilayered rosettes (ETMR) is an aggressive and rare variant of embryonal brain tumors. Amplification of C19MC microRNA cluster…”
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14
Transcriptomic Analysis Revealed an Emerging Role of Alternative Splicing in Embryonal Tumor with Multilayered Rosettes
Published in Genes (22-09-2020)“…Embryonal tumor with multilayered rosettes (ETMR) is an aggressive and rare pediatric embryonal brain tumor. Amplification of C19MC microRNA cluster and…”
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15
LC3A-mediated autophagy elicits PERK-eIF2α-ATF4 axis activation and mitochondrial dysfunction: Exposing vulnerability in aggresome-positive cancer cells
Published in The Journal of biological chemistry (01-06-2024)“…The unfolded protein response pathways (UPR), autophagy, and compartmentalization of misfolded proteins into inclusion bodies are critical components of the…”
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16
Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations
Published in Journal of neuro-oncology (2024)“…Purpose Choroid plexus carcinomas (CPCs) are extremely rare brain tumors and carry a dismal prognosis. Treatment options are limited and there is an urgent…”
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Abstract LB-221: Aggresome-based classification is a promising prognostic marker for pediatric choroid plexus tumors
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Protein misfolding and aggregation result in proteotoxic stress, and underlie the pathogenesis of many diseases. To overcome proteotoxicity, cells…”
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Journal Article -
18
Comparative study of fractional CO 2 laser and fractional CO 2 laser-assisted drug delivery of topical steroid and topical vitamin C in macular amyloidosis
Published in Lasers in medical science (01-05-2018)“…Macular amyloidosis (MA) represents a common variant of primary localized cutaneous amyloidosis. It has a characteristic female predominance; none of the…”
Get full text
Journal Article -
19
Validation of Urinary PD-1 and FOXP3 mRNA in a Cohort of Egyptian Renal Allograft Recipients
Published in Annals of transplantation (12-01-2016)“…We investigated the diagnostic and prognostic value of urinary programmed death 1 (PD-1) and FOXP3 (Forkhead transcription factors) mRNA in acute renal…”
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