Search Results - "Herzog, Ido M"

Cationic Pillararenes Potently Inhibit Biofilm Formation without Affecting Bacterial Growth and Viability by Joseph, Roymon, Naugolny, Alissa, Feldman, Mark, Herzog, Ido M, Fridman, Micha, Cohen, Yoram

“…It is estimated that up to 80% of bacterial infections are accompanied by biofilm formation. Since bacteria in biofilms are less susceptible to antibiotics…”
Get full text

Di-N-Methylation of Anti-Gram-Positive Aminoglycoside-Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram-Negative Bacteria by Benhamou, Raphael I., Shaul, Pazit, Herzog, Ido M., Fridman, Micha

“…The effect of di‐N‐methylation of bacterial membrane disruptors derived from aminoglycosides (AGs) on antimicrobial activity is reported. Di‐N‐methylation of…”
Get full text

Tuning the Effects of Bacterial Membrane Permeability through Photo‐Isomerization of Antimicrobial Cationic Amphiphiles by Salta, Joana, Benhamou, Raphael I., Herzog, Ido M., Fridman, Micha

“…Several important antimicrobial drugs act by permeabilizing cell membranes. In this study, we showed that the intensity of membrane permeability caused by…”
Get full text

Fluorescent Tracking of the Endoplasmic Reticulum in Live Pathogenic Fungal Cells by Benhamou, Raphael I, Jaber, Qais Z, Herzog, Ido M, Roichman, Yael, Fridman, Micha

“…In fungal cells, the endoplasmic reticulum (ER) harbors several of the enzymes involved in the biosynthesis of ergosterol, an essential membrane component,…”
Get full text

Site-Selective Displacement of Tobramycin Hydroxyls for Preparation of Antimicrobial Cationic Amphiphiles by Berkov-Zrihen, Yifat, Herzog, Ido M, Feldman, Mark, Fridman, Micha

“…A short site-selective strategy for the activation and derivatization of alcohols of the clinically important aminoglycoside tobramycin is reported. The choice…”
Get full text

Effects of 5‑O‑Ribosylation of Aminoglycosides on Antimicrobial Activity and Selective Perturbation of Bacterial Translation by Herzog, Ido M, Louzoun Zada, Sivan, Fridman, Micha

“…We studied six pairs of aminoglycosides and their corresponding ribosylated derivatives synthesized by attaching a β-O-linked ribofuranose to the 5-OH of the…”
Get full text

Cationic Amphiphiles Induce Macromolecule Denaturation and Organelle Decomposition in Pathogenic Yeast by Jaber, Qais Z., Benhamou, Raphael I., Herzog, Ido M., Ben Baruch, Bar, Fridman, Micha

“…Cationic amphiphiles are a large and diverse class of antimicrobial agents. Although their mode of action is not fully resolved, it is generally accepted that…”
Get full text

Tobramycin and Nebramine as Pseudo-oligosaccharide Scaffolds for the Development of Antimicrobial Cationic Amphiphiles by Berkov-Zrihen, Yifat, Herzog, Ido M., Benhamou, Raphael I., Feldman, Mark, Steinbuch, Kfir B., Shaul, Pazit, Lerer, Shachar, Eldar, Avigdor, Fridman, Micha

“…Antimicrobial cationic amphiphiles derived from aminoglycoside pseudo‐oligosaccharide antibiotics interfere with the structure and function of bacterial…”
Get full text

6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes by Herzog, Ido M., Green, Keith D., Berkov-Zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Eldar, Avigdor, Garneau-Tsodikova, Sylvie, Fridman, Micha

“…Amphiphilic tobramycin analogues with potent antibacterial activity against tobramycin‐resistant bacteria were synthesized. Most analogues were found to be…”
Get full text

Di-alkylated paromomycin derivatives: Targeting the membranes of Gram positive pathogens that cause skin infections by Berkov-Zrihen, Yifat, Herzog, Ido M., Feldman, Mark, Sonn-Segev, Adar, Roichman, Yael, Fridman, Micha

“…A collection of paromomycin-based di-alkylated cationic amphiphiles differing in the lengths of their aliphatic chain residues were designed, synthesized, and…”
Get full text

Derivatives of Ribosome-Inhibiting Antibiotic Chloramphenicol Inhibit the Biosynthesis of Bacterial Cell Wall by Louzoun Zada, Sivan, Green, Keith D, Shrestha, Sanjib K, Herzog, Ido M, Garneau-Tsodikova, Sylvie, Fridman, Micha

“…Here, we describe the preparation and evaluation of α,β-unsaturated carbonyl derivatives of the bacterial translation inhibiting antibiotic chloramphenicol…”
Get full text

Cationic Amphiphiles Induce Macromolecule Denaturation and Organelle Decomposition in Pathogenic Yeast by Jaber, Qais Z., Benhamou, Raphael I., Herzog, Ido M., Ben Baruch, Bar, Fridman, Micha

“…Cationic amphiphiles are a large and diverse class of antimicrobial agents. Although their mode of action is not fully resolved, it is generally accepted that…”
Get full text

Di-N-Methylation of Anti-Gram-Positive Aminoglycoside-Derived Membrane Disruptors Improves Antimicrobial Potency and Broadens Spectrum to Gram-Negative Bacteria by Benhamou, Raphael I., Shaul, Pazit, Herzog, Ido M., Fridman, Micha

“…The effect of di‐N‐methylation of bacterial membrane disruptors derived from aminoglycosides (AGs) on antimicrobial activity is reported. Di‐N‐methylation of…”
Get full text

Inside Cover: 6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes (Angew. Chem. Int. Ed. 23/2012) by Herzog, Ido M., Green, Keith D., Berkov-Zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Eldar, Avigdor, Garneau-Tsodikova, Sylvie, Fridman, Micha

Get full text

6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes by Herzog, Ido M., Green, Keith D., Berkov-Zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Eldar, Avigdor, Garneau-Tsodikova, Sylvie, Fridman, Micha

“…Amphiphile Analoga von Tobramycin wurden synthetisiert, die gegen tobramycinresistente Bakterien wirken. Die meisten Derivate waren weniger anfällig für eine…”
Get full text

Innentitelbild: 6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes (Angew. Chem. 23/2012) by Herzog, Ido M., Green, Keith D., Berkov-Zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Eldar, Avigdor, Garneau-Tsodikova, Sylvie, Fridman, Micha

“…Amphiphile Aminoglycosid‐Antibiotika töten Bakterien durch Zerstörung ihrer hoch negativ geladenen Membran. In der Zuschrift auf S. 5750 ff. beschreiben M…”
Get full text

6′′‐Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes by Herzog, Ido M., Green, Keith D., Berkov‐Zrihen, Yifat, Feldman, Mark, Vidavski, Roee R., Eldar‐Boock, Anat, Satchi‐Fainaro, Ronit, Eldar, Avigdor, Garneau‐Tsodikova, Sylvie, Fridman, Micha

Get full text