Search Results - "Herzog, C R"

Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016 by Herzog, C.R., Berzins, D.W., DenBesten, P., Gregory, R.L., Hargreaves, K.M., Messer, R.L.W., Mina, M., Mooney, M.P., Paine, M.L., Phillips, C., Presland, R.B., Quivey, R.G., Scannapieco, F.A., Sheridan, J.F., Svoboda, K.K.H., Trackman, P.C., Walker, M.P., Walker, S.G., Wang, C.Y., Hu, J.C.C.

“…For decades, dental schools in the United States have endured a significant faculty shortage. Studies have determined that the top 2 sources of dental faculty…”
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Formation of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in male Fischer-344 rats by Schut, H A, Herzog, C R

“…2-Amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) is known to induce colon tumors in male Fischer-344 rats. Using 32P-postlabeling assays, we have…”
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Sequence variation and chromosomal mapping of the murine Cdkn2a tumor suppressor gene by Herzog, C R, You, M

“…Twenty-nine mouse strains were examined for sequence variation of the Cdkn2a (p16 super(INK4a)) tumor suppressor gene by single-strand conformation…”
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A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression by ZHONGQIU ZHANG, YIAN WANG, HERZOG, Christopher R, GONGJIE LIU, LEE, Han-Woong, DEPINHO, Ronald A, MING YOU

“…Lung cancer is the leading cause of cancer death among both men and women, accounting for more than 28% of all cancer deaths. In fact, more people die of lung…”
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Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Herzog, Christopher R., Desai, Dhimant, Amin, Shantu

“…Exposure to genotoxic carcinogens in tobacco smoke is a major cause of lung cancer. However, the effect this has on DNA copy number and genomic stability…”
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Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression by HERZOG, Christopher R, BODON, Nomar, PITTMAN, Brian, MARONPOT, Robert R, MASSEY, Thomas E, ANDERSON, Marshall W, MING YOU, DEVEREUX, Theodora R

“…Genotoxic carcinogens exert their tumorigenic effects in part by inducing genomic instability. We recently showed that loss of heterozygosity (LOH) on…”
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ras mutations in 2-amino-3-methylimidazo-[4,5-f]quinoline-induced tumors in the CDF1 mouse by Herzog, C R, Schut, H A, Maronpot, R R, You, M

“…2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a very potent mutagen that is carcinogenic in rodents and nonhuman primates. IQ-induced CDF1 mouse lung and…”
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Genetic alterations in mouse lung tumors: Implications for cancer chemoprevention by Herzog, Christopher R., Lubet, Ronald A., You, Ming

“…Specific genetic alterations affecting known tumor suppressor genes and proto‐oncogenes occur during mouse lung tumorigenesis. These include mutational…”
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Allelic loss of distal chromosome 4 in mouse lung tumors localize a putative tumor suppressor gene to a region homologous with human chromosome 1p36 by Herzog, C R, Wang, Y, You, M

“…Loss of heterozygosity (LOH) of distal chromosome 4 was studied to localize a putative tumor suppressor gene in mouse lung neoplasia. Previous studies have…”
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Deletion mapping of a putative tumor suppressor gene on chromosome 4 in mouse lung tumors by Herzog, C R, Wiseman, R W, You, M

“…Genetic and molecular studies have implicated the region of the alpha-interferon gene cluster on mouse chromosome 4 as the location of a putative tumor…”
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Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas by Herzog, Christopher R., Crist, Keith A., Sabourin, Carol L. K., Kelloff, Gary J., Boone, Charles W., Stoner, Gary D., You, Ming

“…Loss of heterozygosity (LOH) on chromosome 3p is a common event in cervical cancer and typically occurs in a dispersed pattern involving several loci. This…”
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INACTIVATION OF BOTH Rb AND p53 PATHWAYS IN MOUSE LUNG EPITHELIAL CELL LINES by McDoniels-Silvers, Amy L., Herzog, Christopher R., Tyson, Frederick L., Malkinson, Alvin M., You, Ming

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Accumulation of DNA adducts of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ) in tissues and white blood cells of the Fischer-344 rat after multiple oral dosing by Schut, H A, Herzog, C R, Cummings, D A

“…The genotoxic effect of an environmental chemical may be estimated from the concentration of its DNA adducts in peripheral white blood cells (WBCs). The food…”
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Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas by Herzog, Christopher R., Chen, Bin, Wang, Yian, Schut, Herman A. J., You, Ming

“…An allelotype analysis of lung tumors in mouse hybrids was conducted to identify common regions of allelic loss. By using 50 informative genetic markers, the…”
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Expression of Cell Cycle Proteins in 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone-Induced Mouse Lung Tumors by Sabourin, Carol L. K., Wang, Qian-Shu, Ralston, Sherry L., Evans, Jason, Coate, Jennifer, Herzog, Christopher R., Jones, Sandra L., Weghorst, Christopher M., Kelloff, Gary J., Lubet, Ronald A., You, Ming, Stoner, Gary D.

“…Cyclin D1 dysregulation and differential inactivation of p16INK4a and Rb have been observed in human lung cancer. In chemically induced mouse lung tumors, the…”
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Tea and cancer prevention: studies in animals and humans by Chung, Fung-Lung, Schwartz, Joel, Herzog, Christopher R, Yang, Yang-Ming

“…The role of tea in protection against cancer has been supported by ample evidence from studies in cell culture and animal models. However, epidemiological…”
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Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53 by SWAMY, Malisetty V, HERZOG, Christopher R, RAO, Chinthalapally V

“…Inactivation of the p53 tumor suppressor gene usually involves somatic mutation or binding of viral oncoproteins to the p53 protein. However, several types of…”
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The 5'-flanking region of the E1 alpha form of the murine p16 super(INK4a) (MTS1) gene by Soloff, E V, Herzog, C R, You, Ming

“…We have PCR-amplified and sequenced the immediate (841 bp) 5'-flanking region of murine p16INK4a (MTS1, CDKN2) tumor suppressor gene. Comparing to recently…”
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Cdkn2a encodes functional variation of p16INK4a but not p19ARF, which confers selection in mouse lung tumorigenesis by Herzog, C R, Noh, S, Lantry, L E, Guan, K L, You, M

“…The cyclin-dependent kinase inhibitor 2a (Cdkn2a) locus encodes two distinct tumor suppressors, p16INK4a and p19ARF, whose functions interrelate in the…”
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Cdkn2a Encodes Functional Variation of p16 super(INK4a) but not p19 super(ARF), Which Confers Selection in Mouse Lung Tumorigenesis by Herzog, C R, Noh, S, Lantry, LE, Guan, K-L, You, M

“…The cyclin-dependent kinase inhibitor 2a (Cdkn2a) locus encodes two distinct tumor suppressors, p16 super(INK4a) and p19 super(ARF), whose functions…”
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