Search Results - "Herzfeldt, Vivian"

Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579 by Pompeu, Thais E.T., Alves, Fernando R.S., Figueiredo, Carolina D.M., Antonio, Camila B., Herzfeldt, Vivian, Moura, Bruna C., Rates, Stela M.K., Barreiro, Eliezer J., Fraga, Carlos A.M., Noël, François

“…In an attempt to increase the affinity of our antipsychotic lead compound LASSBio-579 (1-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine; (2))…”
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Chitosan-coated nanocapsules ameliorates the effect of olanzapine in prepulse inhibition of startle response (PPI) in rats following oral administration by Veragten, Annelieke, Contri, Renata Vidor, Betti, Andresa Heemann, Herzfeldt, Vivian, Frank, Luiza Abrahão, Pohlmann, Adriana Raffin, Rates, Stela Maris Kuze, Guterres, Silvia Stanisçuaski

“…In this study, olanzapine-loaded lipid-core nanocapsules were successfully developed and coated with two different chitosan solutions (same concentration of…”
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PT-31, a putative α2-adrenoceptor agonist, is effective in schizophrenia cognitive symptoms in mice by Betti, Andresa Heemann, Antonio, Camila Boque, Herzfeldt, Vivian, Pitta, Marina Galdino da Rocha, da Rocha Pitta, Ivan, do Rego, Jean-Luc, do Rego, Jean-Claude, Vaudry, David, Rates, Stela Maris Kuze

“…Evidence of changes in central noradrenergic activity has been reported in schizophrenic patients and studies indicate that activation of the α2-adrenoceptor…”
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Synergistic interaction between diene valepotriates from V aleriana glechomifolia Meyer (Valerianaceae) and classical antidepressants: an isobolographic analysis by Müller, Liz G, Stolz, Eveline D, Betti, Andresa H, Herzfeldt, Vivian, Rates, Stela M K

“…Abstract Objectives Combinations of different classes of antidepressants (including herbal adjuvants) have been used as an alternative means of achieving…”
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A valepotriate-enriched fraction from Valeriana glechomifolia decreases DNA methylation and up-regulate TrkB receptors in the hippocampus of mice by Müller, Liz G., Biojone, Caroline, Sales, Amanda J., Betti, Andresa H., Herzfeldt, Vivian, Joca, Sâmia R.L., Rates, Stela M.K.

“…DNA methylation, an epigenetic modification that mediates gene silencing, has been shown to play a role in the neurobiology of major depression. Studies…”
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Synergistic interaction between diene valepotriates from Valeriana glechomifoliaMeyer (Valerianaceae) and classical antidepressants: an isobolographic analysis by Muller, Liz G, Stolz, Eveline D, Betti, Andresa H, Herzfeldt, Vivian, Rates, Stela M K

“…Objectives Combinations of different classes of antidepressants (including herbal adjuvants) have been used as an alternative means of achieving better results…”
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Synergistic interaction between diene valepotriates from Valeriana glechomifolia Meyer (Valerianaceae) and classical antidepressants: an isobolographic analysis by Müller, Liz G., Stolz, Eveline D., Betti, Andresa H., Herzfeldt, Vivian, Rates, Stela M. K.

“…Objectives Combinations of different classes of antidepressants (including herbal adjuvants) have been used as an alternative means of achieving better results…”
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LASSBio-1422: a new molecular scaffold with efficacy in animal models of schizophrenia and disorders of attention and cognition by Betti, Andresa H, Antonio, Camila B, Pompeu, Thais E.T, Martins, Thaise S, Herzfeldt, Vivian, Stolz, Eveline D, Fraga, Carlos A.M, Barreiro, Eliezer, Noël, François, Rates, Stela M.K

“…Aiming to identify new antipsychotic lead-compounds, our group has been working on the design and synthesis of new N-phenylpiperazine derivatives. Here, we…”
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LASSBio-579, a prototype antipsychotic drug, and clozapine are effective in novel object recognition task, a recognition memory model by Antonio, Camila B, Betti, Andresa H, Herzfeldt, Vivian, Barreiro, Eliezer J, Fraga, Carlos A.M, Rates, Stela M.K

“…Previous studies on the N-phenylpiperazine derivative LASSBio-579 have suggested that LASSBio-579 has an atypical antipsychotic profile. It binds to D2, D4 and…”
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Diene Valepotriates from Valeriana glechomifolia Prevent Lipopolysaccharide-Induced Sickness and Depressive-Like Behavior in Mice by Rates, Stela Maris K., Viana, Alice F., Herzfeldt, Vivian, Stolz, Eveline D., Borsoi, Milene, Müller, Liz G., Ravazzolo, Ana Paula

“…Valeriana glechomifolia, a native species from southern Brazil, presents antidepressant-like activity and diene valepotriates (VAL) contribute to the…”
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