Search Results - "Herzer, U."

Interference by Toxic Metal Ions with DNA Repair Processes and Cell Cycle Control: Molecular Mechanisms by Hartwig, A., Asmuss, M., Ehleben, I., Herzer, U., Kostelac, D., Pelzer, A., Schwerdtle, T., Bürkle, A.

“…Nickel, cadmium, cobalt, and arsenic compounds are well-known carcinogens to humans and experimental animals. Even though their DNA-damaging potentials are…”
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Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice by JÄGER, R, HERZER, U, SCHENKEL, J, WEIHER, H

“…Expression of the apoptosis-inhibitory protein Bcl-2 has frequently been detected in human cancer including mammary carcinoma. The functional significance of…”
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The Wilms tumor suppressor gene wt1 is required for development of the spleen by Herzer, Ute, Crocoll, Alexander, Barton, Debra, Howells, Norma, Englert, Christoph

“…The Wilms tumor suppressor gene WT1 (wt1 in mouse) is unique among tumor suppressors because, in addition to its involvement in cancer [1,2] and various other…”
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The speckling domain of the Wilms tumor suppressor WT1 overlaps with the transcriptional repression domain by Herzer, Ute, Lutz, Bertram, Hartmann, Kristina, Englert, Christoph

“…The Wilms tumor suppressor gene WT1 encodes a zinc finger protein, expressed as different splicing variants, that has all the hallmarks of a transcription…”
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138. Purification of Plasmid DNA on an Anion Exchange Column without the Use of RNase To Process Scale by Pitarresi, Tina M, Herzer, Sibylle U, Kennedy, Bob, Moore, Peter

“…We report here the use of a simple, straightforward RNase free method for the purification of plasmid DNA on ANX Sepharose 4 FF high sub exploiting the use of…”
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173. Process Design and Scale-Up of New Vaccine Concepts for Biodefense by Herzer, Sibylle U, Bergvall, Peder, Lemmens, Raf, Coffey, Matt, Leps, Walter T, Moore, Peter M

“…New vaccine delivery constituents such as oligonucleotides, plasmids and infectious non-replicating viruses have created the need to find ways to purify these…”
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174. Process Development of a Scaleable Purification Protocol for the Production of Reolysin, an Oncolytic, Reovirus-Based Therapeutic by Herzer, Sibylle U, Peder, Bergvall, Raf, Lemmens, Matt, Coffey, Peter, Moore M

“…Reovirus is an enterovirus that specifically infects cells with an activated ras-pathway. As the activation of the ras-pathway is a common denominator in a…”
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Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods by Crocoll, Alexander, Herzer, Ute, Ghyselinck, Norbert B, Chambon, Pierre, Cato, Andrew C.B

“…Digit formation during vertebrate limb development is a well-known example of programmed cell death. We have used this system to analyze whether the formation…”
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