Search Results - "Herwig, Martina C"

Genome organization in proximity to the BAP1 locus appears to play a pivotal role in a variety of cancers by Sharma, Amit, Liu, Hongde, Tobar‐Tosse, Fabian, Noll, Angela, Chand Dakal, Tikam, Li, Huamei, Holz, Frank G., Loeffler, Karin U., Herwig‐Carl, Martina C.

“…Cancer studies primarily focus on the characterization of the key driver genes and the underlying pathways. However, the contribution of other…”
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Langerhans Cell Histiocytosis of the Orbit: Five Clinicopathologic Cases and Review of the Literature by Herwig, Martina C., MD, Wojno, Ted, MD, Zhang, Qing, MD, Grossniklaus, Hans E., MD, MBA

“…Abstract Langerhans cell histiocytosis (LCH) is a proliferation of Langerhans cells intermixed with inflammatory cells, in particular eosinophils, that may…”
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Lymphatic markers in the human optic nerve: A previous study on podoplanin immunostaining in fetal eyes did not describe lymphatics in the dura mater by Herwig-Carl (nee Herwig), Martina C., Müller, Annette M., Loeffler, Karin U.

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Distribution and Presumed Proliferation of Macrophages in Inflammatory Diseases of the Ocular Adnexae by Herwig, Martina C., Holz, Frank G., Loeffler, Karin U.

“…ABSTRACT Purpose: The aim of this article is to investigate whether macrophages show a proliferative activity (as indicated by Ki67 expression) and their…”
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Conjunctival Stromal Tumor: Report of 4 Cases by Herwig, Martina C., MD, Wells, Jill R., MD, Grossniklaus, Hans E., MD, MBA

“…Purpose To describe the clinical, histopathologic, immunohistochemical, and ultrastructural features of a case series of benign stromal tumors in the bulbar…”
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Ubiquitin Carboxyl-Terminal Hydrolases (UCHs): Potential Mediators for Cancer and Neurodegeneration by Sharma, Amit, Liu, Hongde, Tobar-Tosse, Fabian, Chand Dakal, Tikam, Ludwig, Michael, Holz, Frank G, Loeffler, Karin U, Wüllner, Ullrich, Herwig-Carl, Martina C

“…Emerging evidence suggests an inverse association between cancer and neurodegenerative diseases (NDD). Although phenotypically different, both diseases display…”
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Dynamics of microcyst-like epithelial changes associated with Belantamab mafodotin therapy in a patient with multiple myeloma—a case report by Schloesser, Lukas, Loeffler, Karin U., Heine, Annkristin, Holz, Frank G., Herwig-Carl, Martina C.

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Morphologic analysis of artifacts in human fetal eyes confounding histopathologic investigations by Herwig, Martina C, Müller, Annette M, Holz, Frank G, Loeffler, Karin U

“…Human fetal eyes are an excellent source for studies of the normal ocular development and for examining early ocular changes associated with various syndromes…”
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Immunolocalization of Different Collagens in the Cornea of Human Fetal Eyes: A Developmental Approach by Herwig, Martina C., Müller, Annette M., Holz, Frank G., Loeffler, Karin U.

“…Purpose: To study the corneal development in the human fetal eye with particular emphasis on the epithelial basement membrane and Bowman's layer. Thus,…”
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Mutational Landscape of the BAP1 Locus Reveals an Intrinsic Control to Regulate the miRNA Network and the Binding of Protein Complexes in Uveal Melanoma by Sharma, Amit, Biswas, Arijit, Liu, Hongde, Sen, Sagnik, Paruchuri, Anoosha, Katsonis, Panagiotis, Lichtarge, Olivier, Chand Dakal, Tikam, Maulik, Ujjwal, Gromiha, M. Michael, Bandyopadhyay, Sanghamitra, Ludwig, Michael, Holz, Frank G., Loeffler, Karin U., Herwig-Carl, Martina C.

“…The BAP1 (BRCA1-associated protein 1) gene is associated with a variety of human cancers. With its gene product being a nuclear ubiquitin carboxy-terminal…”
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Basal cell carcinomas developing independently from BAP1-tumor predisposition syndrome in a patient with bilateral uveal melanoma: Diagnostic challenges to identify patients with BAP1-TPDS by Melzer, Charlotte, Sharma, Amit, Peters, Sophia, Aretz, Stefan, Biswas, Arijit, Holz, Frank G, Loeffler, Karin U, Herwig-Carl, Martina C

“…Basal cell carcinomas (BCC) have been recently included into the spectrum of BAP1-tumor predisposition syndrome (TPDS). Uveal melanoma (UM) is also a tumor…”
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M2/M1 ratio of tumor associated macrophages and PPAR-gamma expression in uveal melanomas with class 1 and class 2 molecular profiles by Herwig, Martina C., Bergstrom, Chris, Wells, Jill R., Höller, Tobias, Grossniklaus, Hans E.

“…Macrophages have been found to be negative predictors of outcome in patients with uveal melanoma. In particular, recent studies point toward a…”
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Regression of Periocular Basal Cell Carcinoma: A Report of Four Cases with Clinicopathologic Correlation by Herwig-Carl, Martina C., Loeffler, Karin U.

“…Objectives: To describe the spectrum of clinical and histopathological features of a case series of basal cell carcinoma (BCC) with spontaneous regression and…”
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Endothelial VE-cadherin expression in human lungs by Herwig, Martina C., Müller, Klaus-Michael, Müller, Annette M.

“…Cell adhesion molecule vascular endothelial cadherin (VE-cadherin) is the major component of endothelial adherence junctions, maintaining endothelial cell…”
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Animal Models of Uveal Melanoma: Methods, Applicability, and Limitations by Herwig, Martina C., Holz, Frank G., Loeffler, Karin U., Stei, Marta M.

“…Animal models serve as powerful tools for investigating the pathobiology of cancer, identifying relevant pathways, and developing novel therapeutic agents…”
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BAP1 Immunostaining in Uveal Melanoma: Potentials and Pitfalls by Herwig-Carl, Martina C., Sharma, Amit, Moulin, Alexandre, Strack, Claudine, Loeffler, Karin U.

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Morphological and Immunohistochemical Changes After Corneal Cross-Linking by Messmer, Elisabeth M, Meyer, Peter, Herwig, Martina C, Loeffler, Karin U, Schirra, Frank, Seitz, Berthold, Thiel, Michael, Reinhard, Thomas, Kampik, Anselm, Auw-Haedrich, Claudia

“…PURPOSE:To present light and electron microscopic as well as immunohistochemical findings after corneal cross-linking (CXL). METHODS:Six keratoconus corneas…”
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Reactive Retinal Astrocytic Tumors (So-called Vasoproliferative Tumors): Histopathologic, Immunohistochemical, and Genetic Studies of Four Cases by Poole Perry, Lynn J, Jakobiec, Frederick A, Zakka, Fouad R, Reichel, Elias, Herwig, Martina C, Perry, Arie, Brat, Daniel J, Grossniklaus, Hans E

“…Purpose To evaluate the cellular nature of and diagnostic terminology used in connection with acquired retinal “vasoproliferative tumors.” Design Retrospective…”
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Melanocytoma of the Conjunctiva: Clinicopathologic Features of Three Cases by Herwig-Carl, Martina C., Loeffler, Karin U., Grossniklaus, Hans E.

“…Background: Melanocytoma (magnocellular nevus) is a jet-black benign lesion histologically composed of polygonal tumor cells with small, inconspicuous nuclei…”
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Diffuse Large B-Cell Lymphoma of the Orbit: Clinicopathologic, Immunohistochemical, and Prognostic Features of 20 Cases by Stacy, Rebecca C, Jakobiec, Frederick A, Herwig, Martina C, Schoenfield, Lynn, Singh, Arun, Grossniklaus, Hans E

“…Purpose To evaluate a series of orbital diffuse large B-cell lymphomas (DLBCL) for prognostic features and therapeutic outcomes. Design Retrospective…”
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