Search Results - "Hervieu, Guillaume"

Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin by Medhurst, Andrew D., Jennings, Carol A., Robbins, Melanie J., Davis, Robert P., Ellis, Catherine, Winborn, Kim Y., Lawrie, Kenneth W. M., Hervieu, Guillaume, Riley, Graham, Bolaky, Jane E., Herrity, Nicole C., Murdock, Paul, Darker, John G.

“…Apelin peptides have recently been identified to be the endogenous ligands for the G protein‐coupled receptor APJ. However, little is known about the…”
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Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake by Bäckberg, Matilda, Hervieu, Guillaume, Wilson, Shelagh, Meister, Björn

“…The neuropeptides orexin‐A and orexin‐B are produced in neurons of the lateral hypothalamic area and have been implicated to be involved in the regulation of…”
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Further insights into the neurobiology of melanin-concentrating hormone in energy and mood balances by Hervieu, Guillaume J

“…Melanin-concentrating hormone (MCH) is a critical hypothalamic anabolic neuropeptide, with key central and peripheral actions on energy balance regulation. The…”
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Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1 by Chambers, Jon, Ames, Robert S, Bergsma, Derk, Muir, Alison, Fitzgerald, Laura R, Hervieu, Guillaume, Dytko, George M, Foley, James J, Martin, John, Liu, Wu-Schyong, Park, Janet, Ellis, Catherine, Ganguly, Subinay, Konchar, Susan, Cluderay, Jane, Leslie, Ron, Wilson, Shelagh, Sarau, Henry M

“…The underlying causes of obesity are poorly understood but probably involve complex interactions between many neurotransmitter and neuropeptide systems…”
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A G Protein-coupled Receptor for UDP-glucose by Chambers, Jon K., Macdonald, Lynn E., Sarau, Henry M., Ames, Robert S., Freeman, Katie, Foley, James J., Zhu, Yuan, McLaughlin, Megan M., Murdock, Paul, McMillan, Lynette, Trill, John, Swift, Ann, Aiyar, Nambi, Taylor, Paul, Vawter, Lisa, Naheed, Sajda, Szekeres, Philip, Hervieu, Guillaume, Scott, Claire, Watson, Jeanette M., Murphy, Andrew J., Duzic, Emir, Klein, Christine, Bergsma, Derk J., Wilson, Shelagh, Livi, George P.

“…Uridine 5′-diphosphoglucose (UDP-glucose) has a well established biochemical role as a glycosyl donor in the enzymatic biosynthesis of carbohydrates. It is…”
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SAR of biphenyl carboxamide ligands of the human melanin-concentrating hormone receptor 1 (MCH R1): Discovery of antagonist SB-568849 by Witty, David R., Bateson, John H., Hervieu, Guillaume J., Jeffrey, Phillip, Johnson, Christopher N., Muir, Alison I., O’Hanlon, Peter J., Stemp, Geoffrey, Stevens, Alex J., Thewlis, Kevin M., Wilson, Shelagh, Winborn, Kim Y.

“…We report here the discovery of a class of MCH R1 ligands based on a biphenyl carboxamide template. A docked-in model is presented indicating key interactions…”
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Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849 by Witty, David R., Bateson, John, Hervieu, Guillaume J., Al-Barazanji, Kamal, Jeffrey, Phillip, Hamprecht, Dieter, Haynes, Andrea, Johnson, Christopher N., Muir, Alison I., O’Hanlon, Peter J., Stemp, Geoffrey, Stevens, Alex J., Thewlis, Kevin, Winborn, Kim Y.

“…A strategy of systematically targeting more rigid analogues of the known MCH R1 receptor antagonist, SB-568849, serendipitously uncovered a binding mode…”
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Schwann cell overexpression of the GPR7 receptor in inflammatory and painful neuropathies by Zaratin, Paola F., Quattrini, Angelo, Previtali, Stefano C., Comi, Giancarlo, Hervieu, Guillaume, Scheideler, Mark A.

“…The human 7-transmembrane receptor GPR7 has sequence similarity to opioid and somatostatin receptors, and can be activated by the recently discovered…”
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Cellular Localization and Role of Prohormone Convertases in the Processing of Pro-melanin Concentrating Hormone in Mammals by Viale, A, Ortola, C, Hervieu, G, Furuta, M, Barbero, P, Steiner, D F, Seidah, N G, Nahon, J L

“…Melanin concentrating hormone (MCH) and neuropeptide EI (NEI) are two peptides produced from the same precursor in mammals, by cleavage at the Arg 145 -Arg 146…”
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Melanin-concentrating hormone functions in the nervous system: food intake and stress by Hervieu, Guillaume

“…Melanin-concentrating hormone (MCH) is a cyclic neuropeptide, which centrally regulates food intake and stress. MCH induces food intake in rodents and, more…”
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Distribution of somatostatin receptor subtypes in rat lumbar spinal cord examined with gold-labelled somatostatin and anti-receptor antibodies by Segond von Banchet, Gisela, Schindler, Marcus, Hervieu, Guillaume J, Beckmann, Barbara, Emson, Piers C, Heppelmann, Bernd

“…Using gold-labelled somatostatin, somatostatin binding sites were predominantly found in laminae I–III, X and on motorneurones of the rat lumbar spinal cord. A…”
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Neuromedin U-R2 localisation in the mouse gastrointestinal tract and the effects of rat NmU-23 by Dass, Narinder B., Bassil, Anna K., Looney, Noeleen A., Corcoran, Stacey L., Hervieu, Guillaume, Sanger, Gareth J.

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Pro-melanin concentrating hormone messenger ribonucleic acid and peptides expression in peripheral tissues of the rat by Hervieu, G, Nahon, J L

“…Melanin-concentrating hormone (MCH) is a cyclic peptide which is predominantly synthetized in the hypothalamus of fish and mammalian brains. In the present…”
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Developmental and Stage-Dependent Expression of Melanin-Concentrating Hormone in Mammalian Germ Cells1 by Hervieu, Guillaume, Segretain, Dominique, Nahon, Jean-Louis

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Rat melanin-concentrating hormone messenger ribonucleic acid expression: marked changes during development and after stress and glucocorticoid stimuli by Presse, F, Hervieu, G, Imaki, T, Sawchenko, P E, Vale, W, Nahon, J L

“…Melanin-concentrating hormone (MCH) is a cyclic neuropeptide first isolated from fish and rats. MCH may be involved in the control of the…”
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Developmental and stage-dependent expression of melanin-concentrating hormone in mammalian germ cells by HERVIEU, G, SEGRETAIN, D, NAHON, J.-L

“…Melanin-concentrating hormone (MCH) is a cyclic peptide predominantly expressed in the hypothalamus of mammals. This peptide modulates the stress response and…”
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Structure and regulation of the melanin-concentrating hormone gene by Nahon, J L, Presse, F, Breton, C, Hervieu, G, Schorpp, M

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