Search Results - "Hertzman, Rebecca J"

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    Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions by Li, Yueran, Deshpande, Pooja, Hertzman, Rebecca J, Palubinsky, Amy M, Gibson, Andrew, Phillips, Elizabeth J

    Published in Frontiers in genetics (16-04-2021)
    “…Adverse drug reactions (ADRs) remain associated with significant mortality. Delayed hypersensitivity reactions (DHRs) that occur greater than 6 h following…”
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    Journal Article
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    Visual Genomics Analysis Studio as a Tool to Analyze Multiomic Data by Hertzman, Rebecca J, Deshpande, Pooja, Leary, Shay, Li, Yueran, Ram, Ramesh, Chopra, Abha, Cooper, Don, Watson, Mark, Palubinsky, Amy M, Mallal, Simon, Gibson, Andrew, Phillips, Elizabeth J

    Published in Frontiers in genetics (17-06-2021)
    “…Type B adverse drug reactions (ADRs) are iatrogenic immune-mediated syndromes with mechanistic etiologies that remain incompletely understood. Some of the most…”
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    Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor by Johnstone, Elizabeth K. M., Ayoub, Mohammed Akli, Hertzman, Rebecca J., See, Heng B., Abhayawardana, Rekhati S., Seeber, Ruth M., Pfleger, Kevin D. G.

    Published in Frontiers in endocrinology (Lausanne) (26-05-2022)
    “…The angiotensin type 2 (AT 2 ) receptor and the bradykinin type 2 (B 2 ) receptor are G protein-coupled receptors (GPCRs) that have major roles in the…”
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    Journal Article
  5. 5

    Immunopharmacogenomics: Mechanisms of HLA‐Associated Drug Reactions by Deshpande, Pooja, Hertzman, Rebecca J., Palubinsky, Amy M., Giles, Jason B., Karnes, Jason H., Gibson, Andrew, Phillips, Elizabeth J.

    Published in Clinical pharmacology and therapeutics (01-09-2021)
    “…The human leukocyte antigen (HLA) system is the most polymorphic in the human genome that has been associated with protection and predisposition to a broad…”
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    Journal Article
  6. 6

    Role of pharmacogenomics in T-cell hypersensitivity drug reactions by Hertzman, Rebecca J., Deshpande, Pooja, Gibson, Andrew, Phillips, Elizabeth J.

    “…Purpose of review An update of the pharmacogenetic risk factors associated with T-cell-mediated delayed hypersensitivity reactions. Recent findings Recent HLA…”
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