Search Results - "Hertz, L."

Assessment of the Clinical Utility of Pretreatment DPYD Testing for Patients Receiving Fluoropyrimidine Chemotherapy by Hertz, Daniel L

“…Patients who carry pathogenic variants in have higher systemic fluoropyrimidine (FP) concentrations and greater risk of severe and fatal FP toxicity…”
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Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update by Loprinzi, Charles L, Lacchetti, Christina, Bleeker, Jonathan, Cavaletti, Guido, Chauhan, Cynthia, Hertz, Daniel L, Kelley, Mark R, Lavino, Antoinette, Lustberg, Maryam B, Paice, Judith A, Schneider, Bryan P, Lavoie Smith, Ellen M, Smith, Mary Lou, Smith, Thomas J, Wagner-Johnston, Nina, Hershman, Dawn L

“…To update the ASCO guideline on the recommended prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathy (CIPN) in…”
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The early development of brain white matter: A review of imaging studies in fetuses, newborns and infants by Dubois, J, Dehaene-Lambertz, G, Kulikova, S, Poupon, C, Hüppi, P.S, Hertz-Pannier, L

“…Graphical abstract…”
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Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group by Caudle, Kelly E., Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Swen, Jesse J., Haidar, Cyrine E., Klein, Teri E., Gammal, Roseann S., Relling, Mary V., Scott, Stuart A., Hertz, Daniel L., Guchelaar, Henk‐Jan, Gaedigk, Andrea

“…Translating CYP2D6 genotype to metabolizer phenotype is not standardized across clinical laboratories offering pharmacogenetic (PGx) testing and PGx clinical…”
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Pre-piRNA trimming safeguards piRNAs against erroneous targeting by RNA-dependent RNA polymerase by Pastore, Benjamin, Hertz, Hannah L., Tang, Wen

“…The Piwi/Piwi-interacting RNA (piRNA) pathway protects genome integrity in animal germ lines. Maturation of piRNAs involves nucleolytic processing at both 5′…”
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C. elegans germ granules sculpt both germline and somatic RNAome by Price, Ian F., Wagner, Jillian A., Pastore, Benjamin, Hertz, Hannah L., Tang, Wen

“…Germ granules are membrane-less organelles essential for small RNA biogenesis and germline development. Among the conserved properties of germ granules is…”
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Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes by Overgaard, Rune V., Hertz, Christin L., Ingwersen, Steen H., Navarria, Andrea, Drucker, Daniel J.

“…Glucagon-like peptide-1 receptor agonists (GLP-1RA) are used for the treatment of type 2 diabetes. Whether clinically important responses and adverse events…”
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Comparative analysis of piRNA sequences, targets and functions in nematodes by Pastore, Benjamin, Hertz, Hannah L., Tang, Wen

“…Piwi proteins and Piwi-interacting RNAs (piRNAs) are best known for their roles in suppressing transposons and promoting fertility. Yet piRNA biogenesis and…”
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Prevalence of drug-drug interactions in oncology patients enrolled on National Clinical Trials Network oncology clinical trials by Marcath, Lauren A, Coe, Taylor D, Hoylman, Emily K, Redman, Bruce G, Hertz, Daniel L

“…Drug-drug interactions (DDIs) in subjects enrolling in clinical trials can impact not only safety of the patient but also study drug outcomes and data…”
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On the variability of reported ionic conductivity in nanoscale YSZ thin films by Jiang, Jun, Hertz, Joshua L.

“…Yttria-stabilized zirconia (YSZ) is the most common material used as a solid oxide electrolyte, which is a key component in solid oxide fuel cells, solid oxide…”
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Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer by Dolan, M Eileen, El Charif, Omar, Wheeler, Heather E, Gamazon, Eric R, Ardeshir-Rouhani-Fard, Shirin, Monahan, Patrick, Feldman, Darren R, Hamilton, Robert J, Vaughn, David J, Beard, Clair J, Fung, Chunkit, Kim, Jeri, Fossa, Sophie D, Hertz, Daniel L, Mushiroda, Taisei, Kubo, Michiaki, Einhorn, Lawrence H, Cox, Nancy J, Travis, Lois B

“…Our purpose was to characterize the clinical influences, genetic risk factors, and gene mechanisms contributing to persistent cisplatin-induced peripheral…”
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Structural Asymmetries in the Infant Language and Sensori-Motor Networks by Dubois, J., Hertz-Pannier, L., Cachia, A., Mangin, J.F., Le Bihan, D., Dehaene-Lambertz, G.

“…Both language capacity and strongly lateralized hand preference are among the most intriguing particularities of the human species. They are associated in the…”
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Drug-drug interactions in subjects enrolled in SWOG trials of oral chemotherapy by Marcath, Lauren A, Finley, Colin M, Wong, Siu Fun, Hertz, Daniel L

“…Patients with cancer are at increased risk of drug-drug interactions (DDI), which can increase treatment toxicity or decrease efficacy. It is especially…”
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Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy by Sun, Yihan, Kim, Jae Hyun, Vangipuram, Kiran, Hayes, Daniel F., Smith, Ellen M. L., Yeomans, Larisa, Henry, N. Lynn, Stringer, Kathleen A., Hertz, Daniel L.

“…Purpose Approximately 25% of breast cancer patients experience treatment delays or discontinuation due to paclitaxel-induced peripheral neuropathy (PN)…”
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Language or music, mother or Mozart? Structural and environmental influences on infants’ language networks by Dehaene-Lambertz, G., Montavont, A., Jobert, A., Allirol, L., Dubois, J., Hertz-Pannier, L., Dehaene, S.

“…Understanding how language emerged in our species calls for a detailed investigation of the initial specialization of the human brain for speech processing…”
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Paclitaxel Plasma Concentration after the First Infusion Predicts Treatment-Limiting Peripheral Neuropathy by Hertz, Daniel L, Kidwell, Kelley M, Vangipuram, Kiran, Li, Feng, Pai, Manjunath P, Burness, Monika, Griggs, Jennifer J, Schott, Anne F, Van Poznak, Catherine, Hayes, Daniel F, Lavoie Smith, Ellen M, Henry, N Lynn

“…Paclitaxel exposure, specifically the maximum concentration ( ) and amount of time the concentration remains above 0.05 μmol/L ( ), has been associated with…”
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Use of pharmacogenetics for predicting cancer prognosis and treatment exposure, response and toxicity by Hertz, Daniel L, McLeod, Howard L

“…Cancer treatment is complicated because of a multitude of treatment options and little patient-specific information to help clinicians choose appropriate…”
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Expression of Nucleoside Transporter in Freshly Isolated Neurons and Astrocytes from Mouse Brain by Li, B., Gu, L., Hertz, L., Peng, L.

“…Nucleoside transporters comprise equilibrative ENT1–4 and concentrative CNT1–3. CNTs transport against an intracellular/extracellular gradient and are…”
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Using Pharmacogene Polymorphism Panels to Detect Germline Pharmacodynamic Markers in Oncology by HERTZ, Daniel L, McLEOD, Howard L

“…The patient (germline) genome can influence the pharmacokinetics and pharmacodynamics of cancer therapy. The field of pharmacogenetics (PGx) has primarily…”
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Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans by Price, Ian F, Hertz, Hannah L, Pastore, Benjamin, Wagner, Jillian, Tang, Wen

“…The germ line produces gametes that transmit genetic and epigenetic information to the next generation. Maintenance of germ cells and development of gametes…”
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