Search Results - "Herts, James"

In vitro modeling of endothelial interaction with macrophages and pericytes demonstrates Notch signaling function in the vascular microenvironment by Tattersall, Ian W., Du, Jing, Cong, Zhuangzhuang, Cho, Bennet S., Klein, Alyssa M., Dieck, Chelsea L., Chaudhri, Reyhaan A., Cuervo, Henar, Herts, James H., Kitajewski, Jan

“…Angiogenesis is regulated by complex interactions between endothelial cells and support cells of the vascular microenvironment, such as tissue myeloid cells…”
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Abstract 1488: A novel Notch4 neutralizing antibody inhibits angiogenesis and tumor growth via a distinct mechanism from endothelial Notch1 inhibition by Naiche, L. A., Swaminathan, Bhairavi, Kato, Yu, Das, Sarita, Eng, Jason W., Raza, Qanber, Thakkar, Krishna, Herts, James H., Emmadi, Rajyasree, Matsui, Junji, Kitajewski, Jan K.

“…Endothelial Notch signaling is critical for tumor angiogenesis and growth. Inhibitors of Notch1 or its ligand Dll4 cause tumor vessel hypersprouting but…”
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Abstract 247: Targeting Notch4 with a novel neutralizing antibody inhibits tumor growth and alters immune cell populations within the tumor microenvironment by Eng, Jason, Naiche, L.A., Swaminathan, Bhairavi, Kato, Yu, Thakkar, Krishna, Vadakath, Rahul, Herts, James, Emmadi, Rajyasree, Matsui, Junji, Kitajewski, Jan

“…Endothelial Notch signaling is critical for tumor angiogenesis and growth. Inhibition of Notch1 or its ligand, Dll4, can induce tumor vessel hypersprouting,…”
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Abstract LB009: Notch4 inhibition by a novel neutralizing antibody reduces tumor progression and increases macrophage recruitment within the tumor microenvironment by Eng, Jason W., Naiche, L.A., Swaminathan, Bhairavi, Kato, Yu, Thakkar, Krishna, Alexander, Katherine Ann, Vadakath, Rahul, Herts, James H., Emmadi, Rajyasree, Matsui, Junji, Kitajewski, Jan K.

“…The Notch signaling pathway, particularly endothelial Notch signaling, plays a key role in tumor formation and angiogenesis. Inhibiting Notch1 or its ligand,…”
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