Search Results - "Hertoghs, Kirsten M. L"
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CD27 Defines Phenotypically and Functionally Different Human NK Cell Subsets
Published in The Journal of immunology (1950) (15-03-2008)“…The absence of the TNF-receptor family member CD27 marks the stable acquisition of cytolytic effector functions by both CD4(+) and CD8(+) T cells. We found…”
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Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation
Published in The Journal of clinical investigation (01-11-2010)“…CD8+ T cells play a critical role in the immune response to viral pathogens. Persistent human cytomegalovirus (HCMV) infection results in a strong increase in…”
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Molecular characterization of HCMV‐specific immune responses: Parallels between CD8+ T cells, CD4+ T cells, and NK cells
Published in European journal of immunology (01-09-2015)“…CD8+ T cells are important for immunity against human cytomegalovirus (HCMV). The HCMV‐specific CD8+ T‐cell response is characterized by the accumulation of…”
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The Transcription Factor Hobit Identifies Human Cytotoxic CD4 + T Cells
Published in Frontiers in immunology (24-03-2017)“…The T cell lineage is commonly divided into CD4-expressing helper T cells that polarize immune responses through cytokine secretion and CD8-expressing…”
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Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation
Published in Nature immunology (01-09-2012)“…Van Gisbergen and colleagues report that Hobit, a homolog of the transcription factor Blimp-1, controls the maintenance of mature mouse natural killer T cells…”
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Use of locked nucleic acid oligonucleotides to add functionality to plasmid DNA
Published in Nucleic acids research (15-10-2003)“…The available reagents for the attachment of functional moieties to plasmid DNA are limiting. Most reagents bind plasmid DNA in a non‐sequence‐ specific…”
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Blimp‐1 homolog Hobit identifies effector‐type lymphocytes in humans
Published in European journal of immunology (01-10-2015)“…Human cytomegalovirus (CMV) induces the formation of effector CD8+ T cells that are maintained for decades during the latent stage of infection. Effector CD8+…”
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Molecular characterization of HCMV-specific immune responses: Parallels between CD8 super(+) T cells, CD4 super(+) T cells, and NK cells
Published in European journal of immunology (01-09-2015)“…CD8 super(+) T cells are important for immunity against human cytomegalovirus (HCMV). The HCMV-specific CD8 super(+) T-cell response is characterized by the…”
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Molecular profiling of cytomegalovirus-induced human CD8^sup +^ T cell differentiation
Published in The Journal of clinical investigation (01-11-2010)“…CD8+ T cells play a critical role in the immune response to viral pathogens. Persistent human cytomegalovirus (HCMV) infection results in a strong increase in…”
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