Search Results - "Hersh, L.B."

Distribution of choline acetyltransferase immunopositive structures in the rat brainstem by Tago, H, McGeer, P L, McGeer, E G, Akiyama, H, Hersh, L B

“…The distribution of neurons, fibers and terminal fields in rat brainstem displaying positive immunoreactivity to a polyclonal antiserum to human placental…”
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Progesterone-regulated cyclic modulation of membrane metalloendopeptidase (enkephalinase) in human endometrium by LINETTE CASEY, M, SMITH, J. W, NAGAI, K, HERSH, L. B, MACDONALD, P. C

“…Membrane metalloendopeptidase (MMEP; EC 3.4.24.11; enkephalinase) catalyzes the degradation of endothelins, enkephalins, atrial natriuretic factor, substance…”
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Degradation of islet amyloid polypeptide by neprilysin by Guan, H., Chow, K. M., Shah, R., Rhodes, C. J., Hersh, L. B.

“…Aims/hypothesis A progressive loss of pancreatic beta cell function, a decrease in beta cell mass and accumulation of islet amyloid is characteristic of type 2…”
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CHOLINERGIC INNERVATION IN THE HUMAN STRIATUM: A THREE-COMPARTMENT MODEL by HOLT, D.J, HERSH, L.B, SAPER, C.B

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Cleavage of substance P to an N-terminal tetrapeptide and a C-terminal heptapeptide by a post-proline Cleaving enzyme from bovine brain by Blumberg, S, Teichberg, V I, Charli, J L, Hersh, L B, McKelvy, J F

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Selective age-related loss of CALBINDIN-D 28k from basal forebrain cholinergic neurons in the common marmoset ( callithrix jacchus) by Wu, C.-K, Nagykery, N, Hersh, L.B, Scinto, L.F.M, Geula, C

“…A significant number of the cholinergic neurons in the basal forebrain of the primate, but not the rodent brain contain the calcium binding protein calbindin-D…”
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Evidence for a deficit in cholinergic interneurons in the striatum in schizophrenia by Holt, D.J., Herman, M.M., Hyde, T.M., Kleinman, J.E., Sinton, C.M., German, D.C., Hersh, L.B., Graybiel, A.M., Saper, C.B.

“…Neurochemical and functional abnormalities of the striatum have been reported in schizophrenic brains, but the cellular substrates of these changes are not…”
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Selective age-related loss of CALBINDIN-D28k from basal forebrain cholinergic neurons in the common marmoset (Callithrix jacchus) by WU, C.-K, NAGYKERY, N, HERSH, L. B, SCINTO, L. F. M, GEULA, C

“…A significant number of the cholinergic neurons in the basal forebrain of the primate, but not the rodent brain contain the calcium binding protein…”
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Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain by Manaye, K.F, Zweig, R, Wu, D, Hersh, L.B, De Lacalle, S, Saper, C.B, German, D.C

“…The pars compacta and pars dissipata of the pedunculopontine nucleus contain cholinergic cell group Ch5, and the laterodorsal tegmental nucleus contains…”
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Neutral endopeptidase inhibits prostate cancer tumorigenesis by reducing FGF-2-mediated angiogenesis by Horiguchi, A, Chen, D Y T, Goodman, O B, Zheng, R, Shen, R, Guan, H, Hersh, L B, Nanus, D M

“…Neutral endopeptidase (NEP) is a cell surface peptidase that catalytically inactivates a variety of physiologically active peptides including basic fibroblast…”
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The hydrolysis of endothelins by neutral endopeptidase 24.11 (enkephalinase) by VIJAYARAGHAVAN, J, SCICLI, A. G, CARRETERO, O. A, SLAUGHTER, C, MOOMAW, C, HERSH, L. B

“…Endothelins 1-3 are a family of 21-amino acid peptides whose structure consists of two rings formed by intra-chain disulfide bonds and a linear "COOH-terminal…”
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Peptidases as potential targets for drug therapy by Safavi, A., Csuhai, E., Hersh, L.B.

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An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex by Lysakowski, A, Wainer, B H, Bruce, G, Hersh, L B

“…The distribution of cholinergic fibers in rat cortex was investigated using choline acetyl-transferase immunohistochemistry. Previous studies have either shown…”
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Mesopontine cholinergic and non-cholinergic neurons in schizophrenia by German, D.C, Manaye, K.F, Wu, D, Hersh, L.B, Zweig, R.M

“…Mesopontine cholinergic neurons influence midbrain dopaminergic neurons, and thalamic and cerebellar structures which have been implicated in the neuroanatomy…”
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Patterns of direct projections from the hippocampus to the medial septum-diagonal band complex: anterograde tracing with Phaseolus vulgaris leucoagglutinin combined with immunohistochemistry of choline acetyltransferase by Gaykema, R P, van der Kuil, J, Hersh, L B, Luiten, P G

“…The projections from the Ammon's horn to the cholinergic cell groups in the medial septal and diagonal band nuclei were investigated with anterograde tracing…”
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Expression of meprin subunit precursors. Membrane anchoring through the beta subunit and mechanism of zymogen activation by JOHNSON, G. D, HERSH, L. B

“…The biosynthesis of the membrane-bound metalloendopeptidase meprin was studied after the introduction of cDNAs encoding the rat meprin alpha and beta subunits…”
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Cloning a rat meprin cDNA reveals the enzyme is a heterodimer by JOHNSON, G. D, HERSH, L. B

“…The structure of the kidney microvillar membrane metallopeptidase meprin (EC 3.4.24.18) from rats has been examined. Previously reported to be a homotetramer,…”
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Trk neurotrophin receptors in cholinergic neurons of patients with Alzheimer's disease by Boissière, F, Hunot, S, Faucheux, B, Hersh, L B, Agid, Y, Hirsch, E C

“…Besides cortical pathology, Alzheimer's disease (AD) is characterized by a loss of cholinergic neurons in the basal forebrain but not in the caudate nucleus,…”
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An AP-2 binding sequence within exon 1 of human and porcine choline acetyltransferase genes enhances transcription in neural cells by Baskin, F, Li, Y-P, Hersh, L B, Davis, R M, Rosenberg, R N

“…The gene for choline acetyltransferase, synthesizing acetylcholine, is induced by several neurotrophic factors. A role for AP-2 in enhancing this transcription…”
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The role of charged transmembrane residues of rVAChT on ACh transport and vesamicol binding by Kim, M.-H., Lu, M., Lim, E.-J., Chai, Y.-G., Hersh, L.B.

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