Search Results - "Herscovitz, H"

Specificity of Lipid Incorporation Is Determined by Sequences in the N-Terminal 37 of ApoB by Carraway, Margaretha, Herscovitz, Haya, Zannis, Vassilis, Small, Donald M

“…The N-terminal 17% of apolipoprotein B (apoB-17) is secreted lipid-poor while apoB-41 particles are secreted with a triacylglycerol (TAG)-rich core. Thus, the…”
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Hypertension exacerbates coronary artery disease in transgenic hyperlipidemic Dahl salt-sensitive hypertensive rats by Herrera, V M, Didishvili, T, Lopez, L V, Zander, K, Traverse, S, Gantz, D, Herscovitz, H, Ruiz-Opazo, N

“…The mechanisms underlying the known interaction of two complex polygenic traits, hypertension and hyperlipidemia, resulting in exacerbation of coronary artery…”
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Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core by Herscovitz, H. (Boston University School of Medicine, Boston, MA.), Kritis, A, Talianidis, I, Zanni, E, Zannis, V, Small, D.M

“…The cDNA encoding the N-terminal 41% of human apolipoprotein B (apoB), apoB-41, was transfected into nonhepatic, nonintestinal, mammary-derived mouse cells…”
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AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells by Zang, Mengwei, Zuccollo, Adriana, Hou, Xiuyun, Nagata, Daisuke, Walsh, Kenneth, Herscovitz, Haya, Brecher, Peter, Ruderman, Neil B, Cohen, Richard A

“…The antidiabetic drug metformin stimulates AMP-activated protein kinase (AMPK) activity in the liver and in skeletal muscle. To better understand the role of…”
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LC-MS-based method for the qualitative and quantitative analysis of complex lipid mixtures by Sommer, Ulf, Herscovitz, Haya, Welty, Francine K., Costello, Catherine E.

“…A simple and robust LC-MS-based methodology for the investigation of lipid mixtures is described, and its application to the analysis of human…”
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Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B by HERSCOVITZ, H, HADZOPOULOU-CLADARAS, M, WALSH, M. T, CLADARAS, C, ZANNIS, V. I, SMALL, D. M

“…The N-terminal 17% of human apolipoprotein B (apoB-17) was expressed in murine C127 cells following transfection with a bovine papilloma virus-based expression…”
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Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs by Herscovitz, H, Gantz, D, Tercyak, A M, Zannis, V I, Small, D M

“…Transfected mouse mammary-derived cells (C127) expressing human apolipoprotein (apo) E (C127E) were used a) to determine whether the lipid-binding character of…”
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Nascent Lipidated Apolipoprotein B Is Transported to the Golgi as an Incompletely Folded Intermediate as Probed by Its Association with Network of Endoplasmic Reticulum Molecular Chaperones, GRP94, ERp72, BiP, Calreticulin, and Cyclophilin B by Zhang, Jianying, Herscovitz, Haya

“…We have previously demonstrated that endoplasmic reticulum (ER)-resident molecular chaperones interact with apolipoprotein B-100 (apoB) during its maturation…”
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Flow cytometric kinetic measurements of neutrophil phospholipase A activation by Meshulam, T, Herscovitz, H, Casavant, D, Bernardo, J, Roman, R, Haugland, R.P., Strohmeier, G.S., Diamond, R.D., Simons, E.R.

“…The interrelationships between activation of phospholipases and neutrophil stimulus-induced Ca2+ responses remain unclear. We report here that immune complexes…”
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Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes by Zoeller, R A, Rangaswamy, S, Herscovitz, H, Rizzo, W B, Hajra, A K, Das, A K, Moser, H W, Moser, A, Lazarow, P B, Santos, M J

“…We have used a fluorescence-activated cytotoxicity protocol, 9-(1'-pyrene)nonanol (P9OH)/UV selection (Morand, O. H., Allen, L.-A. H., Zoeller, R. A., and…”
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Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state by Linnik, K M, Herscovitz, H

“…The present study was undertaken to identify and characterize molecular chaperones that assist in the folding of apolipoprotein (apo) B, a secretory protein…”
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Disulfide Bonds Are Required for Folding and Secretion of Apolipoprotein B Regardless of Its Lipidation State by Burch, William L., Herscovitz, Haya

“…Apolipoprotein (apo) B-100, an essential protein for the assembly and secretion of very low density lipoproteins depends on lipid binding (lipidation) for its…”
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The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins by Herscovitz, H, Derksen, A, Walsh, M T, McKnight, C J, Gantz, D L, Hadzopoulou-Cladaras, M, Zannis, V, Curry, C, Small, D M

“…The N-terminal 17% of apolipoprotein B (apoB-17) readily associates with dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles (MLV) to form large…”
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Specificity of Lipid Incorporation Is Determined by Sequences in the N-Terminal 37 of ApoB by Carraway, Margaretha, Herscovitz, Haya, Zannis, Vassilis, Small, Donald M

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The availability of different sources of cholesterol for bile acid synthesis by cultured chick embryo hepatocytes by Herscovitz, H, Tietz, A

“…The availability of different sources of cholesterol for bile acid synthesis by cultured chick embryo hepatocytes was studied. Mevalonolactone was taken up by…”
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Tradition and change in the Nicaraguan press: newspapers and journalists in a new democratic era by Kodrich, Kris P, Herscovitz, H

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Bile acid synthesis from HDL cholesterol and cholesterol ester by cultured chick embryo hepatocytes by Herscovitz, H, Ronen, I, Bilu, S, Tietz, A

“…A comparison of the uptake and conversion of HDL cholesterol and cholesterol ester to bile acids by chick embryo hepatocytes showed the following. Considerable…”
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