Search Results - "Herrmann, B. G"

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus by Barlow, D. P, Stöger, R, Herrmann, B. G, Saito, K, Schweifer, N

“…T-associated maternal effect (Tme) is the only known maternal-effect mutation in the mouse. The defect is nuclear-encoded and embryos that inherit a deletion…”
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Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction by Smith, J C, Price, B M, Green, J B, Weigel, D, Herrmann, B G

“…The Brachyury (T) gene is required for mesoderm formation in the mouse. In this paper we describe the cloning and expression of a Xenopus homolog of Brachyury,…”
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Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor by Müller, Christoph W, Herrmann, Bernhard G

“…The mouse Brachyury (T) gene is the prototype of a growing family of so-called T-box genes which encode transcriptional regulators and have been identified in…”
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The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo by Schulte-Merker, S, Ho, R K, Herrmann, B G, Nüsslein-Volhard, C

“…Embryos mutant for the T gene, in mice, make insufficient mesoderm and fail to develop a notochord. We report the cloning and sequencing of the T gene in the…”
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The T protein encoded by Brachyury is a tissue‐specific transcription factor by Kispert, A., Koschorz, B., Herrmann, B. G.

“…The mouse Brachyury (T) gene is required for differentiation of the notochord and formation of mesoderm during posterior development. Homozygous embryos…”
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A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance by Herrmann, Bernhard G, Koschorz, Birgit, Wertz, Karin, McLaughlin, K. John, Kispert, Andreas

“…Males heterozygous for the t-haplotype form of mouse chromosome 17 preferentially transmit the t-chromosome to their progeny. Several distorter/sterility loci…”
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The Brachyury gene encodes a novel DNA binding protein by Kispert, A., Herrmann, B.G.

“…Brachyury (T) mutant embryos are deficient in mesoderm formation and do not complete axial development. The notochord is most strongly affected. The T gene is…”
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Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity by Riemer, P, Sreekumar, A, Reinke, S, Rad, R, Schäfer, R, Sers, C, Bläker, H, Herrmann, B G, Morkel, M

“…Colon cancer cells frequently carry mutations that activate the β-catenin and mitogen-activated protein kinase (MAPK) signaling cascades. Yet how oncogenic…”
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Expression pattern of the mouse T gene and its role in mesoderm formation by Wilkinson, David G, Bhatt, Sangita, Herrmann, Bernhard G

“…Formation of mesoderm is a crucial event in vertebrate development, establishing many of the important features of the body. Recent studies have implicated…”
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Immunohistochemical Analysis of the Brachyury Protein in Wild-Type and Mutant Mouse Embryos by Kispert, Andreas, Herrmann, Bernhard G.

“…The murine Brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in…”
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Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta by Kispert, A, Herrmann, B G, Leptin, M, Reuter, R

“…The Brachyury (T) gene is required for notochord differentiation in vertebrates. We have identified a Drosophila gene, the T-related gene (Trg), with high…”
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Rescue of the tail defect of Brachyury mice by STOTT, D, KISPERT, A, HERRMANN, B. G

“…The mouse Brachyury (T) gene is required for normal development of axial structures. Embryos homozygous for the T mutation show severe deficiencies in mesoderm…”
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Cloning of the T gene required in mesoderm formation in the mouse by Herrmann, Bernhard G, Labeit, Siegfried, Poustka, Annemarie, King, Thomas R, Lehrach, Hans

“…The murine developmental mutation T identifies an essential gene in mesoderm formation. Embryos lacking normal gene activity fail to form the notochord, the…”
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Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium by Bernier, G, Vukovich, W, Neidhardt, L, Herrmann, B G, Gruss, P

“…The transcription factor Pax6 is required for eye morphogenesis in humans, mice and insects, and can induce ectopic eye formation in vertebrate and…”
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Wnt3a Plays a Major Role in the Segmentation Clock Controlling Somitogenesis by Aulehla, Alexander, Wehrle, Christian, Brand-Saberi, Beate, Kemler, Rolf, Gossler, Achim, Kanzler, Benoit, Herrmann, Bernhard G

“…The vertebral column derives from somites generated by segmentation of presomitic mesoderm (PSM). Somitogenesis involves a molecular oscillator, the…”
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A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system by Neidhardt, Lorenz M, Kispert, Andreas, Herrmann, B G

“…During vertebrate embryonic development, pairs of metameric units, the somites, bud off at the cranial end of the paraxial mesoderm. The somites soon obtain…”
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A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae by KOSEKI, H, WALLIN, J, WILTING, J, MIZUTANI, Y, KISPERT, A, EBENSPERGER, C, HERRMANN, B. G, CHRIST, B, BALLING, R

“…The notochord plays an important role in the differentiation of the paraxial mesoderm and the neural tube. We have analyzed the role of the notochord in somite…”
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A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras by Rashbass, P, Cooke, L. A, Herrmann, B. G, Beddington, R. S. P

“…Developmental genetics has shown that the Brachyury (T) gene has a key role in mesoderm formation during gastrulation in the mouse. Homozygous embryos have a…”
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A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion by Herrmann, B G, Barlow, D P, Lehrach, H

“…We have examined the molecular organization of a region of mouse chromosome 17 that allows homologous recombination between wild-type and t haplotype…”
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Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos by Herrmann, B G

“…The murine Brachyury (T) gene is required in mesoderm formation. Mutants carrying different T alleles show a graded severity of defects correlated with gene…”
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