Search Results - "Herrgen, Leah"
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Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury in vivo
Published in Development (Cambridge) (01-05-2019)“…Moderate or severe traumatic brain injury (TBI) causes widespread neuronal cell death. Microglia, the resident macrophages of the brain, react to injury by…”
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Dynamics of zebrafish somitogenesis
Published in Developmental dynamics (01-03-2008)“…Vertebrate somitogenesis is a rhythmically repeated morphogenetic process. The dependence of somitogenesis dynamics on axial position and temperature has not…”
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RNA-seq analysis and compound screening highlight multiple signalling pathways regulating secondary cell death after acute CNS injury in vivo
Published in Biology open (04-05-2020)“…Understanding the molecular mechanisms that regulate secondary cell death after acute central nervous system (CNS) injury is critical for the development of…”
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Delayed coupling theory of vertebrate segmentation
Published in HFSP Journal (01-02-2009)“…Rhythmic and sequential subdivision of the elongating vertebrate embryonic body axis into morphological somites is controlled by an oscillating multicellular…”
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Intercellular Coupling Regulates the Period of the Segmentation Clock
Published in Current biology (27-07-2010)“…Coupled biological oscillators can tick with the same period. How this collective period is established is a key question in understanding biological clocks…”
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Mapping neurogenesis onset in the optic tectum of Xenopus laevis
Published in Developmental neurobiology (Hoboken, N.J.) (01-12-2016)“…ABSTRACT Neural progenitor cells have a central role in the development and evolution of the vertebrate brain. During early brain development, neural…”
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Calcium-dependent neuroepithelial contractions expel damaged cells from the developing brain
Published in Developmental cell (08-12-2014)“…Both developing and adult organisms need efficient strategies for wound repair. In adult mammals, wounding triggers an inflammatory response that can…”
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Multiple embryo time-lapse imaging of zebrafish development
Published in Methods in molecular biology (Clifton, N.J.) (2009)“…Understanding the dynamics of developmental and cellular processes requires documentation of their changes with appropriate temporal and spatial resolution…”
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Cutting Edge: Predetermined Avidity of Human CD8 T Cells Expanded on Calibrated MHC/Anti-CD28-Coated Microspheres
Published in The Journal of immunology (1950) (15-11-2003)“…Cytotoxic CD8 T cells are key effectors in the immunotherapy of malignant and viral diseases. However, the lack of efficient methods for their in vitro priming…”
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Intercellular Coupling Regulates the Period of the Segmentation Clock
Published 02-09-2010“…Current Biology 20, 1244-1253 (2010) Coupled biological oscillators can tick with the same period. How this collective period is established is a key question…”
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11
Delayed coupling theory of vertebrate segmentation
Published 17-12-2008“…Rhythmic and sequential subdivision of the elongating vertebrate embryonic body axis into morphological somites is controlled by an oscillating multicellular…”
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