Search Results - "Herreros, Antonio"

Dual role of Snail1 as transcriptional repressor and activator by García de Herreros, Antonio

“…Snail1 transcriptional factor plays a key role in the control of epithelial to mesenchymal transition, a process that remodels tumor cells increasing their…”
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Epithelial–mesenchymal transition in cancer by Moustakas, Aristidis, Herreros, Antonio Garcia

“…[...]one of the very early observations of the EMT (or more properly, of the endothelial–mesenchymal transition (van Meeteren and ten Dijke, ) stems from…”
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SNAIL expression correlates with the translocation of syndecan‑1 intracellular domain into the nucleus in prostate cancer cell lines by Farfan, Nancy, Orellana-Serradell, Octavio, Herrera, Daniela, Chrzanowsky, Dominique, Cubillos, Paulina, Marin, Gabriel, Herreros, Antonio Garcia, Castellon, Enrique A, Contreras, Hector R

“…Zinc finger protein SNAI1 (SNAIL) and zinc finger protein SNAI2 (SLUG) transcription factors promote epithelial-mesenchymal transition, a process through which…”
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PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation by Rodríguez, María Isabel, Peralta-Leal, Andreína, O'Valle, Francisco, Rodriguez-Vargas, José Manuel, Gonzalez-Flores, Ariannys, Majuelos-Melguizo, Jara, López, Laura, Serrano, Santiago, de Herreros, Antonio García, Rodríguez-Manzaneque, Juan Carlos, Fernández, Rubén, Del Moral, Raimundo G, de Almodóvar, José Mariano, Oliver, F Javier

“…PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however,…”
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Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer by CANADAS, Israel, ROJO, Federico, MOJAL, Sergi, DE HERREROS, Antonio García, ROVIRA, Ana, ALBANELL, Joan, ARRIOLA, Edurne, TAUS, Alvaro, ARPI, Oriol, ARUMI-URIA, Montserrat, PIJUAN, Lara, MENENDEZ, Silvia, ZAZO, Sandra, DOMINE, Manuel, SALIDO, Marta

“…Met receptor phosphorylation is associated with poor prognosis in human small cell lung cancer (SCLC). The aim of our work was to investigate the effects of…”
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Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor by Herranz, Nicolás, Pasini, Diego, Díaz, Víctor M, Francí, Clara, Gutierrez, Arantxa, Dave, Natàlia, Escrivà, Maria, Hernandez-Muñoz, Inma, Di Croce, Luciano, Helin, Kristian, García de Herreros, Antonio, Peiró, Sandra

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival by Torres, Sofía, Garcia-Palmero, Irene, Herrera, Mercedes, Bartolomé, Rubén A, Peña, Cristina, Fernandez-Aceñero, M Jesús, Padilla, Guillermo, Peláez-García, Alberto, Lopez-Lucendo, María, Rodriguez-Merlo, Rufo, García de Herreros, Antonio, Bonilla, Félix, Casal, J Ignacio

“…Cancer-associated fibroblasts (CAF) are major mediators in tumor microenvironment. We investigated the changes in protein expression in colon cancer-associated…”
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Bioactivity descriptors for uncharacterized chemical compounds by Bertoni, Martino, Duran-Frigola, Miquel, Badia-i-Mompel, Pau, Pauls, Eduardo, Orozco-Ruiz, Modesto, Guitart-Pla, Oriol, Alcalde, Víctor, Diaz, Víctor M., Berenguer-Llergo, Antoni, Brun-Heath, Isabelle, Villegas, Núria, de Herreros, Antonio García, Aloy, Patrick

“…Chemical descriptors encode the physicochemical and structural properties of small molecules, and they are at the core of chemoinformatics. The broad release…”
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Glutamine-Directed Migration of Cancer-Activated Fibroblasts Facilitates Epithelial Tumor Invasion by Mestre-Farrera, Aida, Bruch-Oms, Marina, Peña, Raúl, Rodríguez-Morató, José, Alba-Castellón, Lorena, Comerma, Laura, Quintela-Fandino, Miguel, Duñach, Mireia, Baulida, Josep, Pozo, Óscar J, García de Herreros, Antonio

“…Tumors are complex tissues composed of transformed epithelial cells as well as cancer-activated fibroblasts (CAF) that facilitate epithelial tumor cell…”
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Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition by Dave, Natàlia, Guaita-Esteruelas, Sandra, Gutarra, Susana, Frias, Àlex, Beltran, Manuel, Peiró, Sandra, de Herreros, Antonio García

“…Snail1 and Zeb1 are E-cadherin-transcriptional repressors induced during epithelial mesenchymal transition (EMT). In this article we have analyzed the factors…”
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A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition by Beltran, Manuel, Puig, Isabel, Peña, Cristina, García, José Miguel, Alvarez, Ana Belén, Peña, Raúl, Bonilla, Félix, de Herreros, Antonio García

“…Expression of Snail1 in epithelial cells triggers an epithelial-mesenchymal transition (EMT). Here, we demonstrate that the synthesis of Zeb2, a…”
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F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check by Díaz, Víctor M, de Herreros, Antonio García

“…Abstract F-box proteins are the key recognition subunit of multimeric E3 ubiquitin ligase complexes that participate in the proteasome degradation of specific…”
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Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis by Escrivà, Maria, Peiró, Sandra, Herranz, Nicolás, Villagrasa, Patricia, Dave, Natàlia, Montserrat-Sentís, Bàrbara, Murray, Stephen A., Francí, Clara, Gridley, Thomas, Virtanen, Ismo, García de Herreros, Antonio

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis by Alba-Castellón, Lorena, Olivera-Salguero, Rubén, Mestre-Farrera, Aida, Peña, Raúl, Herrera, Mercedes, Bonilla, Félix, Casal, J Ignacio, Baulida, Josep, Peña, Cristina, García de Herreros, Antonio

“…Snail1 transcriptional factor is essential for triggering epithelial-to-mesenchymal transition (EMT) and inducing tumor cell invasion. We report here an…”
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TGFβ-Activated USP27X Deubiquitinase Regulates Cell Migration and Chemoresistance via Stabilization of Snail1 by Lambies, Guillem, Miceli, Martina, Martínez-Guillamon, Catalina, Olivera-Salguero, Rubén, Peña, Raúl, Frías, Carolina-Paola, Calderón, Irene, Atanassov, Boyko S, Dent, Sharon Y R, Arribas, Joaquín, García de Herreros, Antonio, Díaz, Víctor M

“…: In cancer cells, epithelial-to-mesenchymal transition (EMT) is controlled by Snail1, a transcriptional factor also required for the activation of…”
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Cancer‐associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients by Herrera, Mercedes, Herrera, Alberto, Domínguez, Gemma, Silva, Javier, García, Vanesa, García, José M., Gómez, Irene, Soldevilla, Beatriz, Muñoz, Concepción, Provencio, Mariano, Campos‐Martin, Yolanda, García de Herreros, Antonio, Casal, Ignacio, Bonilla, Félix, Peña, Cristina

“…Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the…”
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Snail1 transcription factor controls telomere transcription and integrity by Mazzolini, Rocco, Gonzàlez, Núria, Garcia-Garijo, Andrea, Millanes-Romero, Alba, Peiró, Sandra, Smith, Susan, García de Herreros, Antonio, Canudas, Sílvia

“…Abstract Besides controlling epithelial-to-mesenchymal transition (EMT) and cell invasion, the Snail1 transcriptional factor also provides cells with cancer…”
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Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature by HERRERA, Mercedes, ISLAM, Abul B. M. M. K, BONILLA, Félix, PENA, Cristina, HERRERA, Alberto, MARTIN, Paloma, GARCIA, Vanesa, SILVA, Javier, GARCIA, Jose M, SALAS, Clara, CASAL, Ignacio, GARCIA DE HERREROS, Antonio

“…Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment,…”
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Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains by Pascual-Reguant, Laura, Blanco, Enrique, Galan, Silvia, Le Dily, François, Cuartero, Yasmina, Serra-Bardenys, Gemma, Di Carlo, Valerio, Iturbide, Ane, Cebrià-Costa, Joan Pau, Nonell, Lara, de Herreros, Antonio García, Di Croce, Luciano, Marti-Renom, Marc A., Peiró, Sandra

“…Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic regions…”
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Multivesicular GSK3 Sequestration upon Wnt Signaling Is Controlled by p120-Catenin/Cadherin Interaction with LRP5/6 by Vinyoles, Meritxell, Del Valle-Pérez, Beatriz, Curto, Josué, Viñas-Castells, Rosa, Alba-Castellón, Lorena, García de Herreros, Antonio, Duñach, Mireia

“…The Wnt canonical ligands elicit the activation of β-catenin transcriptional activity, a response dependent on, but not limited to, β-catenin stabilization…”
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