Search Results - "Herrero, Ana‐Belén"
-
1
Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia
Published in Clinical and translational medicine (01-02-2021)“…Background Several genetic alterations have been identified as driver events in chronic lymphocytic leukemia (CLL) pathogenesis and oncogenic evolution…”
Get full text
Journal Article -
2
Synergistic effect of Chloroquine and Panobinostat in ovarian cancer through induction of DNA damage and inhibition of DNA repair
Published in Neoplasia (New York, N.Y.) (01-05-2021)“…Ovarian cancer (OC) is the deadliest gynecologic malignancy, which is mainly due to late-stage diagnosis and chemotherapy resistance. Therefore, new and more…”
Get full text
Journal Article -
3
Targeting Ongoing DNA Damage in Multiple Myeloma: Effects of DNA Damage Response Inhibitors on Plasma Cell Survival
Published in Frontiers in oncology (19-05-2017)“…Human myeloma cell lines (HMCLs) and a subset of myeloma patients with poor prognosis exhibit high levels of replication stress (RS), leading to DNA damage. In…”
Get full text
Journal Article -
4
Panobinostat Synergistically Enhances the Cytotoxicity of Microtubule Destabilizing Drugs in Ovarian Cancer Cells
Published in International journal of molecular sciences (27-10-2022)“…Ovarian cancer (OC) is one of the most common gynecologic neoplasia and has the highest mortality rate, which is mainly due to late-stage diagnosis and…”
Get full text
Journal Article -
5
Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity
Published in International journal of molecular sciences (07-07-2022)“…Ovarian cancer (OC) is the most lethal gynecological malignancy; therefore, more effective treatments are urgently needed. We recently reported that…”
Get full text
Journal Article -
6
Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
Published in Frontiers in oncology (13-05-2024)“…Cancer is a global health problem accounting for nearly one in six deaths worldwide. Conventional treatments together with new therapies have increased…”
Get full text
Journal Article -
7
Autophagy, Oxidative Stress, and Alcoholic Liver Disease: A Systematic Review and Potential Clinical Applications
Published in Antioxidants (01-07-2023)“…Ethanol consumption triggers oxidative stress by generating reactive oxygen species (ROS) through its metabolites. This process leads to steatosis and liver…”
Get full text
Journal Article -
8
Factors Regulating microRNA Expression and Function in Multiple Myeloma
Published in Non-coding RNA (16-01-2019)“…Intensive research has been undertaken during the last decade to identify the implication of microRNAs (miRNAs) in the pathogenesis of multiple myeloma (MM)…”
Get full text
Journal Article -
9
DNA Damage Response Alterations in Ovarian Cancer: From Molecular Mechanisms to Therapeutic Opportunities
Published in Cancers (10-01-2023)“…The DNA damage response (DDR), a set of signaling pathways for DNA damage detection and repair, maintains genomic stability when cells are exposed to…”
Get full text
Journal Article -
10
FAM46C controls antibody production by the polyadenylation of immunoglobulin mRNAs and inhibits cell migration in multiple myeloma
Published in Journal of cellular and molecular medicine (01-04-2020)“…FAM46C, frequently mutated in multiple myeloma (MM), has recently been shown to encode a non‐canonical poly(A) polymerase (ncPAP). However, its target mRNAs…”
Get full text
Journal Article -
11
The Hybrid Molecule, Edo-S101, Impairs Double Strand Breaks Repair in Multiple Myeloma and Synergizes with Bortezomib and Dexamethasone
Published in Blood (03-12-2015)“…Introduction. EDO-S101 is a hybrid molecule of bendamustine plus vorinostat, new in its class. Our group has previously demonstrated that EDO-S101 is effective…”
Get full text
Journal Article -
12
Intervención psicomotriz en el Primer Ciclo de Educación Infantil: estimulación de situaciones sensoriomotores
Published in Revista interuniversitaria de formación del profesorado (2000)“…El presente artículo se centra en la educación de la Psicomotrcidad durante el primer ciclo de la educación infantil (0-3 años), una etapa que se caracteriza…”
Get full text
Journal Article