Search Results - "Herrera, Macarena"
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Targeting epigenetic dysregulation in autism spectrum disorders
Published in Trends in molecular medicine (01-11-2024)“…Both genetic and environmental factors can disturb the epigenome, influencing autism spectrum disorders (ASD) development and underlying the heterogenic…”
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Aldehyde dehydrogenase 2 in the spotlight: The link between mitochondria and neurodegeneration
Published in Neurotoxicology (Park Forest South) (01-09-2018)“…•Neurodegenerative diseases are threatening conditions that affect life-quality and life-span of the affected patients.•ALDH2 is a critical enzyme involved in…”
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Novel adenoviral IGF-1 administration modulates the association between depressive symptoms and aging: Does gender matter?
Published in Behavioural brain research (17-10-2019)“…•Frailty phenotype underlies depressive-like symptoms in aged mice model.•Behavior linked to depression is influenced by age and gender.•IGF-1 is capable to…”
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Atypus karschi Dönitz, 1887 (Araneae: Atypidae): An Asian purse-web spider established in Pennsylvania, USA
Published in PloS one (07-07-2022)“…The mygalomorph spiders of the family Atypidae are among the most archaic spiders. The genus Atypus Latreille, 1804 occurs in Eurasia and northern Africa, with…”
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Effect of intra‐BLA overexpression of IGF‐1 on the expression of a contextual fear memory trace
Published in Hippocampus (01-10-2022)“…Growth factors, such as insulin‐like growth factor 1 (IGF‐1), among others are known for their critical involvement in learning and memory processes. IGF‐1…”
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IGF-1 Gene Transfer Modifies Inflammatory Environment and Gene Expression in the Caudate-Putamen of Aged Female Rat Brain
Published in Molecular neurobiology (01-06-2022)“…Brain aging is characterized by chronic neuroinflammation caused by activation of glial cells, mainly microglia, leading to alterations in homeostasis of the…”
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IGF-1 GENE THERAPY ON GLIA CELLS AND DOPAMINERGIC NEURONS INTERACTION IN NEURODEGENERATIVE MODELS
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Early IGF-1 Gene Therapy Prevented Oxidative Stress and Cognitive Deficits Induced by Traumatic Brain Injury
Published in Frontiers in pharmacology (21-06-2021)“…Traumatic Brain Injury (TBI) remains a leading cause of morbidity and mortality in adults under 40 years old. Once primary injury occurs after TBI,…”
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NON-MOTOR SYMPTOMS IN A RAT MODEL OF NEUROTOXICITY INDUCED BY 6-OHDA: EFFECT OF INTRACISTERNAL RAD-IGF1 IN ANXIETY-LIKE BEHAVIOR
Published in IBRO neuroscience reports (01-10-2023)Get full text
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10
Computer‐assisted planning with 3D printing for mandibular reconstruction caused by a mandibular fracture with secondary osteomyelitis: A Case Report
Published in Clinical case reports (01-07-2021)“…Mandibular reconstructions are complex clinical pictures that require careful planning for functional and aesthetic outcomes. Virtual surgical planning and 3D…”
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A new opilioacarid species (Parasitiformes: Opilioacarida) from Crete (Greece) with notes on its karyotype
Published in Acarologia (01-01-2021)“…A new species of opilioacarid mite, Opilioacarus thaleri n. sp., is described from mid-level elevation close to the seashore in Crete (Greece). It was found on…”
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Early Cognitive Impairment Behind Nigrostriatal Circuit Neurotoxicity: Are Astrocytes Involved?
Published in ASN neuro (2020)“…Cognitive dysfunction is one of the most severe nonmotor symptoms of nigrostriatal impairment. This occurs as a result of profound functional and morphological…”
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Distribution of Telomeric Sequences (TTAGGG)n in Rearranged Chromosomes of Phyllotine Rodents (Cricetidae, Sigmodontinae)
Published in Cytogenetic and genome research (01-01-2015)“…Phyllotines are sigmodontine rodents endemic to South America with broad genetic variability, Robertsonian polymorphisms being the most frequent. Moreover,…”
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Potentialities of IGF-1 for regulating oxidative stress in neuroinflammation and neurodegeneration: theoretical review
Published in Exploration of neuroprotective therapy (31-10-2024)“…Insulin-like growth factor-1 (IGF-1) elicits a variety of effects on the regulation of oxidative stress, a topic that remains shrouded in controversy. This…”
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Evaluation of quality of life in Chilean patients with orthognathic surgery. A cohort study
Published in Journal of oral research (2016)“…Objective: To compare the presurgical and immediate postsurgical quality of life in Chilean patients with orthognathic surgery. Material and Methods: Cohort…”
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Science around the world
Published in Trends in molecular medicine (01-11-2024)Get full text
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17
Intramuscular insulin-like growth factor-1 gene therapy modulates reactive microglia after traumatic brain injury
Published in Brain research bulletin (01-10-2021)“…[Display omitted] •Intramuscular IGF-1 gene therapy is able to increase IGF-1 plasma levels.•IGF-1 gene modifies reactive gliosis after TBI.•Intramuscular…”
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IGF-1 gene therapy prevents spatial memory deficits and modulates dopaminergic neurodegeneration and inflammation in a parkinsonism model
Published in Brain, behavior, and immunity (01-07-2024)“…[Display omitted] •IGF-1 gene therapy improves cognitive deficits caused by 6-hydroxydopamine.•IGF-1 gene therapy increases the expression level of tyrosine…”
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Proper Frequency of Perinatal Retinal Waves Is Essential for the Precise Wiring of Visual Axons in Nonimage-Forming Nuclei
Published in The Journal of neuroscience (02-10-2024)“…The development of the visual system is a complex and multistep process characterized by the precise wiring of retinal ganglion cell (RGC) axon terminals with…”
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IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons
Published in Aging (Albany, NY.) (01-11-2022)“…The process of aging is the result of progressive loss of homeostasis and functional body impairment, including the central nervous system, where the…”
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