Search Results - "Herrera, Alex F."
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Polatuzumab Vedotin in Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Published in Journal of clinical oncology (10-01-2020)“…Patients with transplantation-ineligible relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) fare poorly, with limited treatment options. The…”
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Can we cure relapsed/refractory Hodgkin lymphoma without a stem cell transplant?
Published in Haematologica (Roma) (01-08-2023)Get full text
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A multicenter phase 1 study of nivolumab for relapsed hematologic malignancies after allogeneic transplantation
Published in Blood (11-06-2020)“…Programmed cell death-1 (PD-1)/programmed death ligand-1 blockade may potentially augment graft-vs-tumor effects following allogeneic hematopoietic cell…”
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Allogeneic transplant following CAR T-cell therapy for large B-cell lymphoma
Published in Haematologica (Roma) (01-01-2023)“…Allogeneic hematopoietic cell transplantation (alloHCT) can potentially salvage large B-cell lymphoma (LBCL) patients experiencing treatment failure after…”
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Relapsed or Refractory Double-Expressor and Double-Hit Lymphomas Have Inferior Progression-Free Survival After Autologous Stem-Cell Transplantation
Published in Journal of clinical oncology (01-01-2017)“…Purpose Double-hit lymphomas (DHLs) and double-expressor lymphomas (DELs) are subtypes of diffuse large B-cell lymphoma (DLBCL) associated with poor outcomes…”
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Polatuzumab vedotin plus bendamustine and rituximab in relapsed/refractory DLBCL: survival update and new extension cohort data
Published in Blood advances (25-01-2022)“…Polatuzumab vedotin plus bendamustine and rituximab (pola + BR) received regulatory approvals for relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL)…”
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Ibrutinib for the treatment of mantle cell lymphoma
Published in Clinical cancer research (01-11-2014)“…Ibrutinib (PCI-32765)--a potent, covalent inhibitor of Bruton tyrosine kinase (BTK), an important kinase in the B-cell receptor signaling pathway--was recently…”
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Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma
Published in The Journal of clinical investigation (01-02-2022)“…Mantle cell lymphoma (MCL) is a phenotypically and genetically heterogeneous malignancy in which the genetic alterations determining clinical indications are…”
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Noncellular Immune Therapies for Non-Hodgkin Lymphoma
Published in Hematology/oncology clinics of North America (01-08-2019)“…Non-Hodgkin lymphomas (NHL) are a diverse group of diseases, encompassing mature B-cell, T-cell, and natural killer cell malignancies and ranging in behavior…”
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Impact of conditioning regimen intensity on the outcomes of peripheral T‐cell lymphoma, anaplastic large cell lymphoma and angioimmunoblastic T‐cell lymphoma patients undergoing allogeneic transplant
Published in British journal of haematology (01-04-2022)“…Summary There have been no large studies comparing reduced‐intensity/non‐myeloablative conditioning (RIC/NMA) to myeloablative conditioning (MAC) regimens in…”
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Cost-effectiveness of second-line axicabtagene ciloleucel in relapsed refractory diffuse large B-cell lymphoma
Published in Blood (10-11-2022)“…•Second-line axi-cel is provisionally cost-effective in selected primary refractory/early relapsed DLBCL patients at a WTP of $100 000 per QALY.•The…”
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Polatuzumab vedotin plus bendamustine and rituximab or obinutuzumab in relapsed/refractory follicular lymphoma: a phase Ib/II study
Published in Haematologica (Roma) (01-04-2024)“…Follicular lymphoma (FL) is the most common type of indolent non-Hodgkin lymphoma. Despite treatment advances that have improved outcomes for patients with…”
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Management of classical Hodgkin lymphoma: a look at up to date evidence and current treatment approaches
Published in Experimental hematology & oncology (27-12-2022)“…The treatment landscape of classical Hodgkin lymphoma (cHL) has undergone significant changes over the past 20 years. Gradual improvements have been made in…”
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Outcomes of patients with primary central nervous system lymphoma following CD19-targeted chimeric antigen receptor T-cell therapy
Published in Haematologica (Roma) (05-09-2024)Get full text
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Results from a phase I trial of pembrolizumab plus vorinostat in relapsed/refractory B-cell non-Hodgkin lymphoma
Published in Haematologica (Roma) (01-02-2024)“…Outcomes after programmed death-1 (PD-1) blockade in B-cell lymphomas are disappointing with few durable responses. Histone deacetylase inhibitors exhibit…”
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Atezolizumab combined with immunogenic salvage chemoimmunotherapy in patients with transformed diffuse large B-cell lymphoma
Published in Haematologica (Roma) (18-07-2024)“…Patients with relapsed/refractory (R/R) transformed diffuse large B-cell lymphoma (DLBCL) from indolent B-cell lymphomas, including Richter transformation…”
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Low T-cell proportion in the tumor microenvironment is associated with immune escape and poor survival in diffuse large B-cell lymphoma
Published in Haematologica (Roma) (01-08-2023)“…The tumor microenvironment (TME) is important in the pathogenesis and prognosis of lymphoma. Previous studies have demonstrated that features of the diffuse…”
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PTCy-based haploidentical vs matched related or unrelated donor reduced-intensity conditioning transplant for DLBCL
Published in Blood advances (12-02-2019)“…This study retrospectively compared long-term outcomes of nonmyeloablative/reduced intensity conditioning (NMC/RIC) allogeneic hematopoietic cell…”
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