Search Results - "Herrbrich, Phillip E"

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells by Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Herrbrich, Phillip E., Hohm, Sarah A., Lahey, Ryan, Eades, William C., Creer, Michael H., Nolta, Jan A.

“…The development of novel cell-based therapies requires understanding of distinct human hematopoietic stem and progenitor cell populations. We recently isolated…”
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Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity by Hess, David A., Meyerrose, Todd E., Wirthlin, Louisa, Craft, Timothy P., Herrbrich, Phillip E., Creer, Michael H., Nolta, Jan A.

“…Human hematopoietic stem cells (HSCs) are commonly purified by the expression of cell surface markers such as CD34. Because cell phenotype can be altered by…”
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In Vivo Distribution of Human Adipose‐Derived Mesenchymal Stem Cells in Novel Xenotransplantation Models by Meyerrose, Todd E., De Ugarte, Daniel A., Hofling, A. Alex, Herrbrich, Phillip E., Cordonnier, Taylor D., Shultz, Leonard D., Eagon, J. Chris, Wirthlin, Louisa, Sands, Mark S., Hedrick, Marc A., Nolta, Jan A.

“…The potential for human adipose‐derived mesenchymal stem cells (AMSC) to traffic into various tissue compartments was examined using three murine…”
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Comparison of radiolabeled isatin analogs for imaging apoptosis with positron emission tomography by Chen, Delphine L, Zhou, Dong, Chu, Wenhua, Herrbrich, Phillip E, Jones, Lynne A, Rothfuss, Justin M, Engle, Jacquelyn T, Geraci, Marco, Welch, Michael J, Mach, Robert H

“…Abstract Introduction Caspase-3 is one of the executioner caspases activated as a result of apoptosis. Radiolabeled isatins bind to caspase-3 with high…”
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Exploring the Molecular Mechanisms for Enhancing MSC Homing and Lodgement within Sites of Liver Damage/Fibrosis by Herrbrich, Phillip E., Meyerrose, Todd E., Nolta, Jan A.

“…Exogenous stem cells such as human mesenchymal stem cells (MSC) and hematopoietic stem cells (HSC) have been reported to be applicable for tissue repair, as in…”
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Tracking Differential Repopulation Kinetics of Human Hematopoietic Progenitor Cells Using MRI Detection of Nanoparticles by Meyerrose, Todd E., Hope, Andrew J., Lin, Shao P., Herrbrich, Phillip E., Creer, Michael H., Nolta, Jan A.

“…Even within cell populations enriched for hematopoietic stem cells, there exists phenotypic and functional heterogeneity, with subsets of progenitors…”
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Isolation of Human CD34- Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential by Hess, David A., Herrbrich, Phillip E., Wirthlin, Louisa, Craft, Timothy P., Nolta, Jan A.

“…The successful development of stem cell-based therapies requires a thorough understanding of human hematopoietic stem cell (HSC) populations. Human CD34− cells…”
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Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor by Hess, David A., Wirthlin, Louisa, Craft, Timothy P., Bonde, Jesper, Lahey, Ryan W., Hohm, Sarah A., Herrbrich, Phillip E., DiPersio, John F., Devine, Steven M., Nolta, Jan A.

“…Interactions between stromal derived factor-1 (SDF-1 or CXCL12), and its receptor CXCR4 regulate hematopoietic stem and progenitor cell retention in the bone…”
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Naive and Ex Vivo Activated Human T Cells Generate Consistent Engraftment and Lethal Graft-Versus-Host Disease (GvHD) in NOD SCID β 2M Null Mice: A New Xenogeneic Model for GvHD by Nervi, Bruno, Rettig, Michael P., Ritchey, Julie K., Bauer, Gerhard, Walker, Jon, Hess, Dave, Herrbrich, Phillip E., Bonyhadi, Mark, Berenson, Ronald J., Nolta, Jan A., DiPersio, John F.

“…GvHD remains a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusion. The human…”
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Transplanted Human Aldehyde Dehydrogenase Expressing Stem Cells Circulate and Engraft Nonhematopoietic Tissues by Hess, David A., Wirthlin, Louisa, Craft, Timothy C., Herrbrich, Phillip E., Roberts, Marie, Creer, Michael H., Sands, Mark S., Nolta, Jan A.

“…Murine bone marrow (BM)-derived cells can engraft non-hematopoietic organs such as the heart, liver and pancreas, and induce cellular repair after tissue…”
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Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model by Hess, David A., Craft, Timothy P., Wirthlin, Louisa, Herrbrich, Phillip E., Hofling, A. Alex, Sands, Mark S., Nolta, Jan A.

“…Beta-glucuronidase (GUSB) is a lysosomal enzyme expressed in virtually all human and murine cell types. Transplantation of GUSB-expressing human hematopoietic…”
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898. Human Hematopoietic Repopulating Stem and Progenitor Cells Can Be Efficiently Selected Based on High Aldehyde Dehydrogenase Activity by Hess, David A, Meyerrose, Todd E, Wirthlin, Louisa, Herrbrich, Phillip E, Craft, Timothy P, Nolta, Jan A

“…Human hematopoietic stem cells (HSC) are commonly purified by the expression of cell surface markers, such as CD34. Since cell phenotype can be altered by cell…”
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