Search Results - "Herrada, Andres A."
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The role of B cells in COVID-19 infection and vaccination
Published in Frontiers in immunology (30-08-2022)“…B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the…”
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TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines
Published in International journal of molecular sciences (02-12-2019)“…Incidence and mortality of gastric cancer is increasing worldwide, in part, because of the lack of new therapeutic targets to treat this disease. Different…”
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SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism
Published in Signal transduction and targeted therapy (22-09-2021)“…The SARS-CoV-2 infection causes severe immune disruption. However, it is unclear if disrupted immune regulation still exists and pertains in recovered COVID-19…”
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Innate Immune Cells' Contribution to Systemic Lupus Erythematosus
Published in Frontiers in immunology (15-04-2019)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies against nuclear antigens, immune complex…”
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The regulation of DOCK family proteins on T and B cells
Published in Journal of leukocyte biology (01-02-2021)“…The dedicator of cytokinesis (DOCK) family proteins consist of 11 members, each of which contains 2 domains, DOCK homology region (DHR)‐1 and DHR‐2, and as…”
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Adipose tissue macrophages as a therapeutic target in obesity‐associated diseases
Published in Obesity reviews (01-06-2021)“…Summary Obesity is an increasing problem in developed and developing countries. Individuals with obesity have a higher risk of several diseases, such as…”
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Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity
Published in The Journal of immunology (1950) (01-04-2012)“…Dendritic cells (DCs) are responsible for priming T cells and for promoting their differentiation from naive T cells into appropriate effector cells. Emerging…”
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Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis
Published in The Journal of experimental medicine (04-09-2017)“…Myelopoiesis is necessary for the generation of mature myeloid cells during homeostatic turnover and immunological insults; however, the metabolic requirements…”
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Spironolactone Decreases DOCA–Salt–Induced Organ Damage by Blocking the Activation of T Helper 17 and the Downregulation of Regulatory T Lymphocytes
Published in Hypertension (Dallas, Tex. 1979) (01-04-2014)“…Adaptive immune response has been implicated in inflammation and fibrosis as a result of exposure to mineralocorticoids and a high-salt diet. We hypothesized…”
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The meningeal lymphatic vasculature in neuroinflammation
Published in The FASEB journal (01-05-2022)“…The lymphatic vasculature is a unidirectional network of lymphatic endothelial cells, whose main role is to maintain fluid homeostasis along with the…”
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Neu1 deficiency and fibrotic lymph node microenvironment lead to imbalance in M1/M2 macrophage polarization
Published in Frontiers in immunology (13-09-2024)“…Macrophages play a pivotal role in tissue homeostasis, pathogen defense, and inflammation resolution. M1 and M2 macrophage phenotypes represent two faces in a…”
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Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy
Published in International journal of molecular sciences (26-05-2023)“…Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the…”
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Aldosterone Promotes Autoimmune Damage by Enhancing Th17-Mediated Immunity
Published in The Journal of immunology (1950) (01-01-2010)“…Excessive production of aldosterone leads to the development of hypertension and cardiovascular disease by generating an inflammatory state that can be…”
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The role of regulatory T cells and follicular T helper cells in HBV infection
Published in Frontiers in immunology (19-05-2023)“…Hepatitis B has become one of the major global health threats, especially in developing countries and regions. Hepatitis B virus infection greatly increases…”
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DOCK2 couples with LEF-1 to regulate B cell metabolism and memory response
Published in Biochemical and biophysical research communications (20-08-2020)“…Dedicator of cytokinesis 2 (DOCK2) is essential for the B cell differentiation, BCR signaling and humoral immune response. However, the role of DOCK2 in the…”
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Yerba Mate ( Ilex paraguariensis ) Reduces Colitis Severity by Promoting Anti-Inflammatory Macrophage Polarization
Published in Nutrients (25-05-2024)“…Yerba Mate (YM) ( ) is a natural herbal supplement with a well-described anti-inflammatory capacity and beneficial effects in different inflammatory contexts…”
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The role of ubiquitinase in B cell development and function
Published in Journal of leukocyte biology (01-02-2021)“…Ubiquitinases are a select group of enzymes that modify target proteins through ubiquitination, which plays a crucial role in the regulation of protein…”
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Lymph Leakage Promotes Immunosuppression by Enhancing Anti-Inflammatory Macrophage Polarization
Published in Frontiers in immunology (19-05-2022)“…Lymphatic vasculature is a network of capillaries and vessels capable of draining extracellular fluid back to blood circulation and to facilitate immune cell…”
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Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines?
Published in Vaccines (Basel) (30-05-2017)“…The lethality of infectious diseases has decreased due to the implementation of crucial sanitary procedures such as vaccination. However, the resurgence of…”
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Aldosterone as a modulator of immunity: implications in the organ damage
Published in Journal of hypertension (01-09-2011)“…High plasmatic levels of aldosterone cause hypertension and contribute to progressive organ damage to the heart, vasculature, and kidneys. Recent studies have…”
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