Search Results - "Herrán, Enara"

VEGF-releasing biodegradable nanospheres administered by craniotomy: A novel therapeutic approach in the APP/Ps1 mouse model of Alzheimer's disease by Herrán, Enara, Pérez-González, Rocio, Igartua, Manoli, Pedraz, José Luis, Carro, Eva, Hernández, Rosa María

“…This study attempts to develop a novel nanotechnology-based strategy to deliver vascular endothelial growth factor (VEGF) to the brain, as a possible…”
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In vivo administration of VEGF- and GDNF-releasing biodegradable polymeric microspheres in a severe lesion model of Parkinson’s disease by Herrán, Enara, Ruiz-Ortega, José Ángel, Aristieta, Asier, Igartua, Manoli, Requejo, Catalina, Lafuente, José Vicente, Ugedo, Luisa, Pedraz, José Luis, Hernández, Rosa María

“…In this work, the neuroregenerative potentials of microencapsulated VEGF, GDNF and their combination on a severely lesioned rat model were compared with the…”
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Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson's disease by Herrán, Enara, Requejo, Catalina, Ruiz-Ortega, Jose Angel, Aristieta, Asier, Igartua, Manoli, Bengoetxea, Harkaitz, Ugedo, Luisa, Pedraz, Jose Luis, Lafuente, Jose Vicente, Hernández, Rosa Maria

“…Current research efforts are focused on the application of growth factors, such as glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial…”
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Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene by Vallejo-Diez, Sara, Fleischer, Aarne, Martín-Fernández, Jose María, Sánchez-Gilabert, Almudena, Castresana, Mónica, Aguillón, David, Villegas, Andrés, Mastronardi, Claudio A., Espinosa, Lady G., Arcos-Burgos, Mauricio, del Pozo, Ángel, Herrán, Enara, Gainza, Eusebio, Isaza-Ruget, Mario, Lopera, Francisco, Bachiller, Daniel

“…The mutation E280A in PSEN1 (presenilin-1) is the most common cause of early-onset familial Alzheimer's Disease (fAD). It presents autosomal dominant…”
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Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation by Hernando, Sara, Requejo, Catalina, Herran, Enara, Ruiz-Ortega, Jose Angel, Morera-Herreras, Teresa, Lafuente, Jose Vicente, Ugedo, Luisa, Gainza, Eusebio, Pedraz, Jose Luis, Igartua, Manoli, Hernandez, Rosa Maria

“…Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been widely associated to beneficial effect over different neurodegenerative diseases. In the present…”
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Nanostructured Lipid Carriers Made of Ω-3 Polyunsaturated Fatty Acids: In Vitro Evaluation of Emerging Nanocarriers to Treat Neurodegenerative Diseases by Hernando, Sara, Herran, Enara, Hernandez, Rosa Maria, Igartua, Manoli

“…Neurodegenerative diseases (ND) are one of the main problems of public health systems in the 21st century. The rise of nanotechnology-based drug delivery…”
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Multifunctional hydrogel-based scaffold for improving the functionality of encapsulated therapeutic cells and reducing inflammatory response by Acarregui, Argia, Herrán, Enara, Igartua, Manoli, Blanco, Francisco Javier, Pedraz, José Luis, Orive, Gorka, Hernandez, Rosa Maria

“…[Display omitted] Since the introduction of cell immunoisolation as an alternative to protect transplanted cells from host immune attack, much effort has been…”
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Chitosan coated nanostructured lipid carriers for brain delivery of proteins by intranasal administration by Gartziandia, Oihane, Herran, Enara, Pedraz, Jose Luis, Carro, Eva, Igartua, Manoli, Hernandez, Rosa Maria

“…[Display omitted] •Design and optimization of a chitosan coated nanostructured lipid carrier (CS-NLC) with the capacity to reach the brain after being…”
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Intranasal Administration of TAT-Conjugated Lipid Nanocarriers Loading GDNF for Parkinson’s Disease by Hernando, Sara, Herran, Enara, Figueiro-Silva, Joana, Pedraz, José Luis, Igartua, Manoli, Carro, Eva, Hernandez, Rosa Maria

“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder (ND), characterized by the loss of dopaminergic neurons, microglial activation,…”
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Advances in nanomedicine for the treatment of Alzheimer's and Parkinson's diseases by Hernando, Sara, Gartziandia, Oihane, Herran, Enara, Pedraz, Jose Luis, Igartua, Manoli, Hernandez, Rosa Maria

“…Alzheimer's disease and Parkinson's disease are the most common neurodegenerative diseases worldwide. Despite all the efforts made by the scientific community,…”
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Design of a composite drug delivery system to prolong functionality of cell-based scaffolds by Murua, Ainhoa, Herran, Enara, Orive, Gorka, Igartua, Manoli, Blanco, Francisco Javier, Pedraz, José Luis, Hernández, Rosa Mª

“…Co-implantation of DXM-loaded PLGA microspheres resulted in improved functionality of the cell-based grafts during 45 days in allogeneic mice. Cell…”
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