Search Results - "Herr, R. R"

Role of the Prefrontal Cortex in Pain Processing by Ong, Wei-Yi, Stohler, Christian S., Herr, Deron R.

“…The prefrontal cortex (PFC) is not only important in executive functions, but also pain processing. The latter is dependent on its connections to other areas…”
Get full text

G protein-coupled receptor GPR19 regulates E-cadherin expression and invasion of breast cancer cells by Rao, Angad, Herr, Deron R.

“…Dysregulation of G protein-coupled receptors (GPCRs) is known to be involved in the pathogenesis of a variety of diseases, including cancer initiation and…”
Get full text

Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells by Thirunavukkarasan, Madhumathi, Wang, Chao, Rao, Angad, Hind, Tatsuma, Teo, Yuan Ru, Siddiquee, Abrar Al-Mahmood, Goghari, Mohamed Ally Ibrahim, Kumar, Alan Prem, Herr, Deron R

“…Short chain fatty acids (2 to 6 carbons in length) are ubiquitous lipids that are present in human plasma at micromolar concentrations. In addition to serving…”
Get full text

5-Substituted-1H-tetrazoles as carboxylic acid isosteres: Medicinal chemistry and synthetic methods by HERR, R. Jason

“…5-Substituted-1H-tetrazoles (RCN4H) are often used as metabolism-resistant isosteric replacements for carboxylic acids (RCO2H) in SAR-driven medicinal…”
Get full text

LPA Receptors: Subtypes and Biological Actions by JI WOONG CHOI, HERR, Deron R, CHUN, Jerold, NOGUCHI, Kyoko, YUNG, Yun C, LEE, Chang-Wook, MUTOH, Tetsuji, LIN, Mu-En, TEO, Siew T, PARK, Kristine E, MOSLEY, Alycia N

“…Lysophosphatidic acid (LPA) is a small, ubiquitous phospholipid that acts as an extracellular signaling molecule by binding to and activating at least five…”
Get full text

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P₁) modulation by Choi, Ji Woong, Gardell, Shannon E, Herr, Deron R, Rivera, Richard, Lee, Chang-Wook, Noguchi, Kyoko, Teo, Siew Teng, Yung, Yun C, Lu, Melissa, Kennedy, Grace, Chun, Jerold

“…Sphingosine 1-phosphate (S1P), a lysophospholipid, has gained relevance to multiple sclerosis through the discovery of FTY720 (fingolimod), recently approved…”
Get full text

Global Distribution and Richness of Armillaria and Related Species Inferred From Public Databases and Amplicon Sequencing Datasets by Koch, Rachel A., Herr, Joshua R.

“…Armillaria is a globally distributed fungal genus most notably composed of economically important plant pathogens that are found predominantly in forest and…”
Get full text

Phenotypic Optimization of Urea–Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss by Chowdhury, Sarwat, Owens, Kelly N, Herr, R. Jason, Jiang, Qin, Chen, Xinchao, Johnson, Graham, Groppi, Vincent E, Raible, David W, Rubel, Edwin W, Simon, Julian A

“…Hearing loss is a major public health concern with no pharmaceutical intervention for hearing protection or restoration. Using zebrafish neuromast hair cells,…”
Get full text

Improving Taxonomic Delimitation of Fungal Species in the Age of Genomics and Phenomics by Stengel, Ashley, Stanke, Kimberly M, Quattrone, Amanda C, Herr, Joshua R

“…Species concepts have long provided a source of debate among biologists. These lively debates have been important for reaching consensus on how to communicate…”
Get full text

A Three-Step Method for the Preparation of N‑Substituted 3,4-Dihydroisoquinolin-1(2H)‑ones and Heteroaryl-Fused 3,4-Dihydropyridin-2(1H)‑ones from 2‑Bromobenzoate Precursors by Freeman, Emily E., Jackson, Randy, Luo, Jessica, Somwaru, Rajen, Sons, Alex A., Bean, Andrew, Buckle, Ronald N., Herr, R. Jason

“…We demonstrate a general method for the preparation of diverse N-substituted 3,4-dihydroisoquinolin-1­(2H)-one compounds through an overall three-step…”
Get full text

The association between diabetes and an episode of depressive symptoms in the 2002 World Health Survey: an analysis of 231 797 individuals from 47 countries by Mommersteeg, P. M. C., Herr, R., Pouwer, F., Holt, R. I. G., Loerbroks, A.

“…Aims Depression is common in people with diabetes and increases the risk of poor health outcomes, including premature mortality. We explored the association…”
Get full text

Virtual reality for persistent pain: A new direction for behavioral pain management by Keefe, Francis J., Huling, Dane A., Coggins, Michael J., Keefe, Daniel F., Zachary Rosenthal, M., Herr, Nathaniel R., Hoffman, Hunter G.

“…Although research on virtual reality interventions for persistent pain is in its infancy, this technology holds considerable promise, and research in this…”
Get full text

Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans by Ong, Wei-Yi, Herr, Deron R, Sun, Grace Y, Lin, Teng-Nan

“…Recent studies on the ethnomedicinal use of suggest promising anti-inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the…”
Get full text

Metagenomic Profiling Reveals Lignocellulose Degrading System in a Microbial Community Associated with a Wood-Feeding Beetle by Scully, Erin D, Geib, Scott M, Hoover, Kelli, Tien, Ming, Tringe, Susannah G, Barry, Kerrie W, Glavina del Rio, Tijana, Chovatia, Mansi, Herr, Joshua R, Carlson, John E, Oliveira, Pedro Lagerblad

“…The Asian longhorned beetle (Anoplophora glabripennis) is an invasive, wood-boring pest that thrives in the heartwood of deciduous tree species. A large…”
Get full text

Differences in the ultrastructure of neurons in the spinal ganglion and dorsal rootlet between rats treated with cisplatin only versus co-administration with a sphingosine 1-phosphate receptor 2 agonist in attenuating neuropathy and allodynia by Chayaburakul, Kanokporn, Ong, Wei Yi, Herr, Deron R, Kobutree, Phetnarin, Chantra, Kraisri

“…Cisplatin is a chemotherapeutic agent for many types of cancer. The neurotoxicity of cisplatin includes neuropathy and allodynia. We aimed to study structural…”
Get full text

Effect of Ergothioneine on 7-Ketocholesterol-Induced Endothelial Injury by Koh, Sally Shuxian, Ooi, Samantha Chia-Yi, Lui, Natalie Man-Yin, Qiong, Cao, Ho, Leona Ting-Yuke, Cheah, Irwin Kee-Mun, Halliwell, Barry, Herr, Deron R., Ong, Wei-Yi

“…Ergothioneine (ET) is a naturally occurring antioxidant that is synthesized by non-yeast fungi and certain bacteria. ET is not synthesized by animals,…”
Get full text

Association analyses of host genetics, root-colonizing microbes, and plant phenotypes under different nitrogen conditions in maize by Meier, Michael A, Xu, Gen, Lopez-Guerrero, Martha G, Li, Guangyong, Smith, Christine, Sigmon, Brandi, Herr, Joshua R, Alfano, James R, Ge, Yufeng, Schnable, James C, Yang, Jinliang

“…The root-associated microbiome (rhizobiome) affects plant health, stress tolerance, and nutrient use efficiency. However, it remains unclear to what extent the…”
Get full text

Lysophosphatidic acid and its receptor LPA1 mediate carrageenan induced inflammatory pain in mice by Srikanth, Malavika, Chew, Wee Siong, Hind, Tatsuma, Lim, Siew Mon, Hay, Nicholas Wei Jie, Lee, Jasmine Hui Min, Rivera, Rich, Chun, Jerold, Ong, Wei-Yi, Herr, Deron R.

“…Lysophosphatidic acid receptor 1 (LPA1) is one of six G protein-coupled receptors (GPCRs) activated by the bioactive lipid, lysophosphatidic acid (LPA)…”
Get full text

Towards the unification of sequence-based classification and sequence-based identification of host-associated microorganisms by Herr, Joshua R, Opik, Maarja, Hibbett, David S

Get full text

Transcriptomics Reveals the Putative Mycoparasitic Strategy of the Mushroom Entoloma abortivum on Species of the Mushroom Genus Armillaria by Koch, Rachel A., Herr, Joshua R.

“…During mycoparasitism, a fungus—the host—is parasitized by another fungus—the mycoparasite. The genetic underpinnings of these relationships have been best…”
Get full text