Search Results - "Herr, Florence"

Circulating CASK is associated with recurrent focal segmental glomerulosclerosis after transplantation by Beaudreuil, Severine, Zhang, Xiaomeng, Herr, Florence, Harper, Francis, Candelier, Jean Jacques, Fan, Ye, Yeter, Hilal, Dudreuilh, Caroline, Lecru, Lola, Vazquez, Aime, Charpentier, Bernard, Lorenzo, Hans K, Durrbach, Antoine

“…Focal and Segmental GlomeruloSclerosis (FSGS) can cause nephrotic syndrome with a risk of progression to end-stage renal disease. The idiopathic form has a…”
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CASK, the Soluble Glomerular Permeability Factor, Is Secreted by Macrophages in Patients With Recurrent Focal and Segmental Glomerulo-Sclerosis by Zhang, Xiaomeng, Herr, Florence, Vernochet, Amelia, Lorenzo, Hans K, Beaudreuil, Séverine, Dürrbach, Antoine

“…Focal and segmental glomerulosclerosis (FSGS) is a frequent form of glomerulonephritis that may be caused by a soluble permeability factor and regulated by the…”
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mTOR Inhibition Impairs the Activation and Function of Belatacept-Resistant CD4 + CD57 + T Cells In Vivo and In Vitro by Herr, Florence, Dekeyser, Manon, Le Pavec, Jerome, Desterke, Christophe, Chiron, Andrada-Silvana, Bargiel, Karen, Mercier, Olaf, Vernochet, Amelia, Fadel, Elie, Durrbach, Antoine

“…Calcineurin inhibitors have improved graft survival in solid-organ transplantation but their use is limited by toxicity, requiring a switch to another…”
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SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production by Roders, Nathalie, Herr, Florence, Ambroise, Gorbatchev, Thaunat, Olivier, Portier, Alain, Vazquez, Aimé, Durrbach, Antoine

“…B cells play a major role in the antibody-mediated rejection (AMR) of solid organ transplants, a major public health concern. The germinal center (GC) is…”
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Impact of DSA and immunosuppression minimization on rejection, graft, and patient survival after simultaneous liver–kidney transplantation by Dekeyser, Manon, Taupin, Jean-Luc, Elias, Michelle, Ichaï, Philippe, Herr, Florence, Boudon, Marc, Brunel, Melanie, Sa cunha, Antonio, Coilly, Audrey, Saliba, Faouzi, Durrbach, Antoine

“…Background Acute rejection rate is low after simultaneous liver–kidney transplantation (SLKT), leading some groups to minimize immunosuppressive (IS) regimens…”
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Mycophenolic acid-treated dendritic cells generate regulatory CD4+ T cells that suppress CD8+ T cells' allocytotoxicity by Kazma, Ihab, Lemoine, Roxane, Herr, Florence, Chadet, Stephanie, Meley, Daniel, Velge-Roussel, Florence, Lebranchu, Yvon, Baron, Christophe

“…Regulatory T cells (Treg) play a crucial role in controlling immunity and transplant rejection. Two main groups of Treg have been described: antigen-induced…”
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Human Fetal Liver Mesenchymal Stem Cell-Derived Exosomes Impair Natural Killer Cell Function by Fan, Ye, Herr, Florence, Vernochet, Amelia, Mennesson, Benoît, Oberlin, Estelle, Durrbach, Antoine

“…Mesenchymal stem cells (MSCs) are powerful immunomodulators that regulate the diverse functions of immune cells involved in allogeneic reactions, such as T…”
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The proliferation of belatacept‐resistant T cells requires early IFNα pathway activation by Herr, Florence, Desterke, Christophe, Bargiel, Karen, Vernochet, Amelia, Vanhove, Bernard, Vadanici, Radu, Ye, Fan, Dekeyser, Manon, Durrbach, Antoine

“…Belatacept was developed to replace calcineurin inhibitors in kidney transplantation. Its use is associated with better kidney transplant function, a lower…”
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Co-stimulation Blockade Plus T-Cell Depletion in Transplant Patients: Towards a Steroid- and Calcineurin Inhibitor-Free Future? by Herr, Florence, Brunel, Melanie, Roders, Nathalie, Durrbach, Antoine

“…Long-term survival of solid allografts depends on both immunosuppressive efficacy and reducing the side effects associated with these therapies…”
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CD57+ CD4 T Cells Underlie Belatacept‐Resistant Allograft Rejection by Espinosa, J., Herr, F., Tharp, G., Bosinger, S., Song, M., Farris, A. B., George, R., Cheeseman, J., Stempora, L., Townsend, R., Durrbach, A., Kirk, A. D.

“…Belatacept is a B7‐specific fusion protein used to prevent allograft rejection by blocking T cell costimulation. Generally efficacious, it fails to prevent…”
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IL-2 phosphorylates STAT5 to drive IFN-γ production and activation of human dendritic cells by Herr, Florence, Lemoine, Roxane, Gouilleux, Fabrice, Meley, Daniel, Kazma, Ihab, Heraud, Audrey, Velge-Roussel, Florence, Baron, Christophe, Lebranchu, Yvon

“…Human dendritic cells (hDCs) produce IL-2 and express IL-2R α-chain (CD25), but the role of IL-2 in DC functions is not well defined. A recent study suggested…”
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Allogeneic CD4 T Cells Sustain Effective BK Polyomavirus-Specific CD8 T Cell Response in Kidney Transplant Recipients by Dekeyser, Manon, de Goër de Herve, Marie-Ghislaine, Hendel-Chavez, Houria, Lhotte, Romain, Scriabine, Ivan, Bargiel, Karen, Boutin, Emmanuelle, Herr, Florence, Taupin, Jean-Luc, Taoufik, Yassine, Durrbach, Antoine

“…BK polyomavirus-associated nephropathy (BKPyVAN) is a significant complication in kidney transplant recipients (KTRs), associated with a higher level of…”
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Immature human dendritic cells enhance their migration through KCa3.1 channel activation by Crottès, David, Félix, Romain, Meley, Daniel, Chadet, Stéphanie, Herr, Florence, Audiger, Cindy, Soriani, Olivier, Vandier, Christophe, Roger, Sébastien, Angoulvant, Denis, Velge-Roussel, Florence

“…Graphical abstract…”
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Immunosuppressive Properties of Mesenchymal Stem Cells by Brunel, Melanie, Herr, Florence, Durrbach, Antoine

“…The properties of mesenchymal stem cells (MSCs) have become better known over the past decade and show potentially attractive new capabilities in solid-organ…”
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Interferon gamma licensing of human dendritic cells in T-helper–independent CD8+ alloimmunity by Lemoine, Roxane, Velge-Roussel, Florence, Herr, Florence, Felix, Romain, Nivet, Hubert, Lebranchu, Yvon, Baron, Christophe

“…The high frequency of allogeneic reactive CD8+ T cells in human and their resistance to immunosuppression might be one of the reasons why successful…”
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Mycophenolic acid-treated dendritic cells generate regulatory CD4 super(+) T cells that suppress CD8 super(+) T cells' allocytotoxicity by Kazma, Ihab, Lemoine, Roxane, Herr, Florence, Chadet, Stephanie, Meley, Daniel, Velge-Roussel, Florence, Lebranchu, Yvon, Baron, Christophe

“…Human iT sub(reg) cells regulate CD8 super(+) T cell cytotoxicity Human iT sub(reg) cells regulate CD8 super(+) T cell cytotoxicity…”
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Pharmacokinetic and pharmacodynamic studies of two different rabbit antithymocyte globulin dosing regimens: Results of a randomized trial by Büchler, Matthias, Longuet, Hélène, Lemoine, Roxane, Herr, Florence, Gatault, Philippe, Thibault, Gilles, Ternant, David, Foulon, Christine, Pilorge, Bernadette, Lemay, Djamila, Sung, Crystal, Halimi, Jean-Michel, Baron, Christophe, Lebranchu, Yvon

“…Abstract Rabbit antithymocyte globulin (rATG; Thymoglobulin® ) is currently used to prevent acute rejection in kidney transplantation. The dose and regimen of…”
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Direct CD4 help provision following interaction of memory CD4 and CD8 T cells with distinct antigen-presenting dendritic cells by de Goër de Herve, Marie-Ghislaine, Dembele, Bamory, Vallée, Mélissa, Herr, Florence, Cariou, Anne, Taoufik, Yassine

“…Accumulating evidence suggests that CD4 help is needed at the memory stage to mount effective secondary CD8 T cell responses. In this paper, we report that…”
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