Search Results - "Herr, Anabel"
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1
Pumilio facilitates miRNA regulation of the E2F3 oncogene
Published in Genes & development (15-02-2012)“…E2F transcription factors are important regulators of cell proliferation and are frequently dysregulated in human malignancies. To identify novel regulators of…”
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2
Torso-like functions independently of Torso to regulate Drosophila growth and developmental timing
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2013)“…Activation of the Drosophila receptor tyrosine kinase Torso (Tor) only at the termini of the embryo is achieved by the localized expression of the maternal…”
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3
Geminin regulates neuronal differentiation by antagonizing Brg1 activity
Published in Genes & development (15-07-2005)“…Precise control of cell proliferation and differentiation is critical for organogenesis. Geminin (Gem) has been proposed to link cell cycle exit and…”
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4
Mutation of Drosophila Lsd1 Disrupts H3-K4 Methylation, Resulting in Tissue-Specific Defects during Development
Published in Current biology (01-05-2007)“…Histone-tail modifications play a fundamental role in the processes that establish chromatin structure and determine gene expression [1–4]. One such…”
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5
A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour
Published in PloS one (18-04-2012)“…For insects the sense of smell and associated olfactory-driven behaviours are essential for survival. Insects detect odorants with families of olfactory…”
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6
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis
Published in Genes & development (15-10-2001)“…We have identified a Drosophila homolog of the DNA replication initiation inhibitor Geminin (Dm geminin) and show that it has all of the properties of Xenopus…”
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7
Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila
Published in Developmental biology (01-08-2010)“…Geminin was identified in Xenopus as a dual function protein involved in the regulation of DNA replication and neural differentiation. In Xenopus, Geminin acts…”
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8
APC/CFzr/Cdh1 promotes cell cycle progression during the Drosophila endocycle
Published in Development (Cambridge) (15-04-2008)“…The endocycle is a commonly observed variant cell cycle in which cells undergo repeated rounds of DNA replication with no intervening mitosis. How the cell…”
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9
E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8
Published in Nature (London) (25-09-2008)“…CCK8 and WNT signalling linked in colorectal cancer The WNT/ β-catenin signalling pathway, which normally plays a pivotal part in development, is deregulated…”
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10
RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3
Published in Genes & development (15-04-2008)“…The Drosophila retinoblastoma family of proteins (RBF1 and RBF2) and their mammalian homologs (pRB, p130, and p107) are best known for their regulation of the…”
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11
Torso-like mediates extracellular accumulation of Furin-cleaved Trunk to pattern the Drosophila embryo termini
Published in Nature communications (28-10-2015)“…Patterning of the Drosophila embryonic termini is achieved by localized activation of the Torso receptor by the growth factor Trunk. Governing this event is…”
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12
Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation
Published in Developmental dynamics (01-11-2012)“…Background: Microarray studies have shown that the E2F transcription factor influences the expression of many genes but it is unclear how many of these targets…”
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13
APC/C super(Fzr/Cdh1) promotes cell cycle progression during the Drosophila endocycle
Published in Development (Cambridge) (01-04-2008)“…The endocycle is a commonly observed variant cell cycle in which cells undergo repeated rounds of DNA replication with no intervening mitosis. How the cell…”
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14
E2F1 represses bold beta-catenin transcription and is antagonized by both pRB and CDK8
Published in Nature (25-09-2008)“…The E2F1 transcription factor can promote proliferation or apoptosis when activated, and is a key downstream target of the retinoblastoma tumour suppressor…”
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15
E2F1 represses -catenin transcription and is antagonized by both pRB and CDK8
Published in Nature (London) (25-09-2008)“…The E2F1 transcription factor can promote proliferation or apoptosis when activated, and is a key downstream target of the retinoblastoma tumour suppressor…”
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16
A Screen for Modifiers of Cyclin E Function in Drosophila melanogaster Identifies Cdk2 Mutations, Revealing the Insignificance of Putative Phosphorylation Sites in Cdk2
Published in Genetics (Austin) (01-05-2000)“…In higher eukaryotes, cyclin E is thought to control the progression from G1 into S phase of the cell cycle by associating as a regulatory subunit with cdk2…”
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