Search Results - "Herold, K."

Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar by Jevtovic-Todorovic, V, Absalom, A.R., Blomgren, K, Brambrink, A, Crosby, G, Culley, D.J., Fiskum, G, Giffard, R.G., Herold, K.F., Loepke, A.W., Ma, D, Orser, B.A., Planel, E, Slikker, W, Soriano, S.G., Stratmann, G, Vutskits, L, Xie, Z, Hemmings, H.C.

“…Although previously considered entirely reversible, general anaesthesia is now being viewed as a potentially significant risk to cognitive performance at both…”
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Teplizumab treatment may improve C-peptide responses in participants with type 1 diabetes after the new-onset period: a randomised controlled trial by Herold, K. C., Gitelman, S. E., Willi, S. M., Gottlieb, P. A., Waldron-Lynch, F., Devine, L., Sherr, J., Rosenthal, S. M., Adi, S., Jalaludin, M. Y., Michels, A. W., Dziura, J., Bluestone, J. A.

“…Aims/hypothesis Type 1 diabetes results from a chronic autoimmune process continuing for years after presentation. We tested whether treatment with teplizumab…”
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rise and fall of insulin secretion in type 1 diabetes mellitus by Tsai, E. B, Sherry, N. A, Palmer, J. P, Herold, K. C

“…An understanding of the natural history of beta cell responses is an essential prerequisite for interventional studies designed to prevent or treat type 1…”
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Unmethylated Insulin DNA Is Elevated After Total Pancreatectomy With Islet Autotransplantation: Assessment of a Novel Beta Cell Marker by Bellin, M. D., Clark, P., Usmani‐Brown, S., Dunn, T. B., Beilman, G. J., Chinnakotla, S., Pruett, T. L., Ptacek, P., Hering, B. J., Wang, Z., Gilmore, T., Wilhelm, J. J., Hodges, J. S., Moran, A., Herold, K. C.

“…Beta cell death may occur both after islet isolation and during infusion back into recipients undergoing total pancreatectomy with islet autotransplantation…”
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Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane by Purtell, K., Gingrich, K.J., Ouyang, W., Herold, K.F., Hemmings, H.C.

“…The mechanisms by which volatile anaesthetics such as isoflurane alter neuronal function are poorly understood, in particular their presynaptic mechanisms…”
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Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol–Lactones as Protein Kinase C Ligands by Ohashi, Nami, Kobayashi, Ryosuke, Nomura, Wataru, Kobayakawa, Takuya, Czikora, Agnes, Herold, Brienna K, Lewin, Nancy E, Blumberg, Peter M, Tamamura, Hirokazu

“…Protein kinase C (PKC) mediates a central cellular signal transduction pathway involved in disorders such as cancer and Alzheimer’s disease. PKC is regulated…”
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Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1) by Pearce, Larry V, Ann, Jihyae, Jung, Aeran, Thorat, Shivaji A, Herold, Brienna K. A, Habtemichael, Amelework D, Blumberg, Peter M, Lee, Jeewoo

“…Transient receptor potential vanilloid 1 (TRPV1) has emerged as a promising therapeutic target. While radiolabeled resiniferatoxin (RTX) has provided a…”
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Analysis of Human Biologics With a Mouse Skin Transplant Model in Humanized Mice by Waldron‐Lynch, F., Deng, S., Preston‐Hurlburt, P., Henegariu, O., Herold, K. C.

“…Preclinical testing of human therapeutic monoclonal antibodies has been limited in murine models due to species differences in pharmacokinetics and biologic…”
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Expectations and emotions concerning infant transitions to ECEC: international dialogues with parents and teachers by White, E. J., Rutanen, N., Marwick, H., Amorim, K. Souza, Karagiannidou, E., Herold, L. K. M.

“…Although a large body of literature recognises the impact of parent-teacher relationships on infant everyday experiences, less is known about the emotional…”
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Effects of Insulin in Relatives of Patients with Type 1 Diabetes Mellitus

“…Persons who are at high risk for type 1 diabetes may be identified on the basis of islet-cell antibody levels, insulin antibody levels, and genetic studies…”
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Patient Willingness to Pay for a Kidney for Transplantation by Herold, D. K.

“…While kidney transplantation is the most cost‐effective treatment available for end‐stage renal disease (ESRD) and affords patients with the best quality of…”
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Blockade of RAGE Suppresses Alloimmune Reactions In Vitro and Delays Allograft Rejection in Murine Heart Transplantation by Moser, B., Szabolcs, M. J., Ankersmit, H. J., Lu, Y., Qu, W., Weinberg, A., Herold, K. C., Schmidt, A. M.

“…The receptor for advanced glycation endproducts (RAGE), a multiligand member of the immunoglobulin superfamily, interacts with proinflammatory AGEs, the…”
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Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation by Glaser, Benjamin, Kesavan, Prebakaran, Heyman, Mozhgan, Davis, Elizabeth, Cuesta, Antonio, Buchs, Andreas, Stanley, Charles A, Thornton, Paul S, Permutt, M. Alan, Matschinsky, Franz M, Herold, Kevan C

“…Spontaneous hyperinsulinemic hypoglycemia in adults is most frequently caused by sporadic, solitary pancreatic beta-cell tumors, whereas hyperinsulinemic…”
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Blockade of RAGE suppresses alloimmune reactions in vitro and delays allograft rejection in murine heart transplantation by MOSER, B, SZABOLCS, M. J, ANKERSMIT, H. J, LU, Y, QU, W, WEINBERG, A, HEROLD, K. C, SCHMIDT, A. M

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Results following completion of phase I clinical trial using ex vivo expanded CD4+CD127lo/-CD25+ polyclonal tregs for the treatment of recent-onset type 1 diabetes by Putnam, A.L, Lares, A, Liu, W, Lee, M, Gitelman, S, Herold, K, Warner, N, Bluestone, J

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Relapsing and Remitting Severe Hypoglycemia due to a Monoclonal Anti-insulin Antibody Heralding a Case of Multiple Myeloma by Waldron-Lynch, F, Inzucchi, S. E, Menard, L, Tai, N, Preston-Hurlburt, P, Hui, P, McClaskey, J, Hagopian, W. A, Meffre, E, Marks, P. W, Wen, L, Herold, K. C

“…Context: We report a novel case of insulin autoimmune syndrome (IAS) presenting with hypoglycemia due to production of a monoclonal anti-insulin antibody in a…”
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Suppression of the human spinal H-reflex by propofol: a quantitative analysis by Baars, J. H., Dangel, C., Herold, K. F., Hadzidiakos, D. A., Rehberg, B.

“…Background:  The spinal cord is an important site of anaesthetic action because it mediates surgical immobility. During anaesthesia with volatile anaesthetics,…”
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Concentration-dependent suppression of F-waves by sevoflurane does not predict immobility to painful stimuli in humans by Baars, J.H., Kalisch, D., Herold, K.F., Hadzidiakos, D.A., Rehberg, B.

“…Decreased spinal excitability contributes to the immobilizing effects of halogenated ethers during general anaesthesia. Recurrent spinal responses such as…”
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Surface tension of aqueous lithium bromide with heat/mass transfer enhancement additives: the effect of additive vapor transport by Kulankara, S, Herold, K.E

“…Heat/mass transfer enhancement additives used in aqueous lithium bromide absorption chillers are surfactants that lower the surface tension of the working…”
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The suppression of spinal F-waves by propofol does not predict immobility to painful stimuli in humans by Baars, J.H., Tas, S, Herold, K.F., Hadzidiakos, D.A., Rehberg, B

“…The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which…”
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