Search Results - "Herok, Silke"

Design and Quantitative Structure−Activity Relationship of 3-Amidinobenzyl-1H-indole-2-carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa by Matter, Hans, Defossa, Elisabeth, Heinelt, Uwe, Blohm, Peter-Michael, Schneider, Detlev, Müller, Andrea, Herok, Silke, Schreuder, Herman, Liesum, Alexander, Brachvogel, Volker, Lönze, Petra, Walser, Armin, Al-Obeidi, Fahad, Wildgoose, Peter

“…A series of 138 nonchiral 3-amidinobenzyl-1H-indole-2-carboxamides and analogues as inhibitors of the blood coagulation enzyme factor Xa (fXa) were designed,…”
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Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors by HEINELT, Uwe, HEROK, Silke, MATTER, Hans, WILDGOOSE, Peter

“…Starting from the achiral and potent factor Xa inhibitor 1, a new and flexible solid-phase optimisation strategy is described to reduce its cationic character…”
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Design and Quantitative Structure−Activity Relationship of 3-Amidinobenzyl-1 H -indole-2-carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa by Matter, Hans, Defossa, Elisabeth, Heinelt, Uwe, Blohm, Peter-Michael, Schneider, Detlev, Müller, Andrea, Herok, Silke, Schreuder, Herman, Liesum, Alexander, Brachvogel, Volker, Lönze, Petra, Walser, Armin, Al-Obeidi, Fahad, Wildgoose, Peter

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