Search Results - "Herndon, Mary E."
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The highly metastatic 4T1 breast carcinoma model possesses features of a hybrid epithelial-mesenchymal phenotype
Published in Disease models & mechanisms (01-09-2024)“…Epithelial-mesenchymal transitions (EMTs) are thought to promote metastasis via downregulation of E-cadherin and upregulation of mesenchymal markers such as…”
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Interaction of Cartilage Oligomeric Matrix Protein/Thrombospondin 5 with Aggrecan
Published in The Journal of biological chemistry (24-08-2007)“…Cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) is a major component of the extracellular matrix (ECM) of the musculoskeletal system. Its…”
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Integrin α3β1 regulates tumor cell responses to stromal cells and can function to suppress prostate cancer metastatic colonization
Published in Clinical & experimental metastasis (01-04-2013)“…Integrin α3β1 promotes tumor cell adhesion, migration, and invasion on laminin isoforms, and several clinical studies have indicated a correlation between…”
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CD151 promotes α3β1 integrin-dependent organization of carcinoma cell junctions and restrains collective cell invasion
Published in Cancer biology & therapy (30-10-2015)“…Integrins function in collective migration both as major receptors for extracellular matrix and by crosstalk to adherens junctions. Despite extensive research,…”
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Expression of α5 integrin rescues fibronectin responsiveness in NT2N CNS neuronal cells
Published in Journal of neuroscience research (01-01-2010)“…The extracellular matrix protein fibronectin is implicated in neuronal regeneration in the peripheral nervous system. In the central nervous system (CNS),…”
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Integrin α3β1 can function to promote spontaneous metastasis and lung colonization of invasive breast carcinoma
Published in Molecular cancer research (01-01-2014)“…Significant evidence implicates α3β1 integrin in promoting breast cancer tumorigenesis and metastasis-associated cell behaviors in vitro and in vivo. However,…”
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Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
Published in Journal of cellular biochemistry (01-03-2004)“…The amino‐terminal domain of the extracellular matrix (ECM) protein thrombospondin‐1 (TSP‐1) mediates binding to cell surface heparan sulfate proteoglycans…”
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Interdomain Interaction of Merlin Isoforms and Its Influence on Intermolecular Binding to NHE-RF
Published in The Journal of biological chemistry (26-11-1999)“…Merlin, the neurofibromatosis 2 tumor suppressor protein, has two major isoforms with alternate C termini and is related to the ERM ( e zrin, r adixin, m…”
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Interactions of neural glycosaminoglycans and proteoglycans with protein ligands: assessment of selectivity, heterogeneity and the participation of core proteins in binding
Published in Glycobiology (Oxford) (01-02-1999)“…The method of affinity coelectrophoresis was used to study the binding of nine representative glycosaminoglycan (GAG)-binding proteins, all thought to play…”
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A diverse set of developmentally regulated proteoglycans is expressed in the rat central nervous system
Published in Neuron (Cambridge, Mass.) (01-06-1990)“…Cellular interactions in neural development are influenced by various extracellular proteins, many of which bind glycosaminoglycans or proteoglycans. Precise…”
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The cell biology of thrombospondin-1
Published in Matrix Biology (01-12-2000)“…Thrombospondin-1 (TSP-1) is a matricellular protein that regulates cellular phenotype during tissue genesis and repair. It acts as a molecular facilitator by…”
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Book Review Journal Article -
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Expression of alpha5 integrin rescues fibronectin responsiveness in NT2N CNS neuronal cells
Published in Journal of neuroscience research (01-01-2010)“…The extracellular matrix protein fibronectin is implicated in neuronal regeneration in the peripheral nervous system. In the central nervous system (CNS),…”
Get full text
Journal Article -
14
Integrin [alpha]3[beta]1 regulates tumor cell responses to stromal cells and can function to suppress prostate cancer metastatic colonization
Published in Clinical & experimental metastasis (20-05-2013)“…Integrin [alpha]3[beta]1 promotes tumor cell adhesion, migration, and invasion on laminin isoforms, and several clinical studies have indicated a correlation…”
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Journal Article -
15
Interaction of Cartilage Oligomeric Matrix Protein/Thrombospondin 5 with Aggrecan,S
Published in The Journal of biological chemistry (22-06-2007)“…Cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) is a major component of the extracellular matrix (ECM) of the musculoskeletal system. Its…”
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Journal Article -
16
Elicitation of an oxidase activity in bacterial luciferase by site-directed mutation of a noncatalytic residue
Published in The Journal of biological chemistry (15-03-1990)“…Flavin-dependent external monooxygenases and oxidases could catalyze the same flavin oxidation reaction involving distinct mechanisms. To gain insights into…”
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