Search Results - "Hernando, Raymundo"

Plasma BDNF levels vary in relation to body weight in females by Pillai, Anilkumar, Bruno, Davide, Sarreal, Antero S, Hernando, Raymundo T, Saint-Louis, Leslie A, Nierenberg, Jay, Ginsberg, Stephen D, Pomara, Nunzio, Mehta, Pankaj D, Zetterberg, Henrik, Blennow, Kaj, Buckley, Peter F

“…Brain derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression as well as neuropsychiatric and neurodegenerative disorders…”
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Lower CSF Amyloid Beta Peptides and Higher F2-Isoprostanes in Cognitively Intact Elderly Individuals With Major Depressive Disorder by Pomara, Nunzio, Bruno, Davide, Sarreal, Antero S., Hernando, Raymundo T., Nierenberg, Jay, Petkova, Eva, Sidtis, John J., Wisniewski, Thomas M., Mehta, Pankaj D., Pratico, Domenico, Zetterberg, Henrik, Blennow, Kaj

“…Objective:Major depressive disorder is common in the elderly, and symptoms are often not responsive to conventional antidepressant treatment, especially in the…”
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State-dependent alterations in cerebrospinal fluid Aβ42 levels in cognitively intact elderly with late-life major depression by Pomara, Nunzio, Bruno, Davide, Osorio, Ricardo S, Reichert, Chelsea, Nierenberg, Jay, Sarreal, Antero S, Hernando, Raymundo T, Marmar, Charles R, Wisniewski, Thomas, Zetterberg, Henrik, Blennow, Kaj

“…Depression has been linked to Alzheimer’s disease as either an increased risk factor for its development or as a prodromal symptom. The neurobiological basis…”
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Increased Mental Slowing Associated With the APOE ε4 Allele After Trihexyphenidyl Oral Anticholinergic Challenge in Healthy Elderly by Pomara, Nunzio, M.D, Belzer, Ken, Ph.D, Sidtis, John J., Ph.D, Hernando, Raymundo, M.D, De La Pena, Corazon, M.D

“…Objectives The objectives of this study were to examine the relationship between APOE ε4 and subjective effects of trihexyphenidyl on measures reflecting…”
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The effect of mifepristone (RU 486) on plasma cortisol in Alzheimer's disease by Pomara, Nunzio, Hernando, Raymundo T, de la Pena, Corazon B, Sidtis, John J, Cooper, Thomas B, Ferris, Steven

“…The glucocorticoid receptor (GR) antagonist mifepristone (RU-486) has been reported to increase early morning plasma ACTH/cortisol in diverse non-demented…”
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Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease by Franzmeier, Nicolai, Neitzel, Julia, Rubinski, Anna, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Hansson, Oskar, Ewers, Michael

“…In Alzheimer’s diseases (AD), tau pathology is strongly associated with cognitive decline. Preclinical evidence suggests that tau spreads across connected…”
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Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology by Shen, Xinpeng, Ma, Sisi, Vemuri, Prashanthi, Simon, Gyorgy

“…Causal Structure Discovery (CSD) is the problem of identifying causal relationships from large quantities of data through computational methods. With the…”
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Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease by Pichet Binette, Alexa, Franzmeier, Nicolai, Spotorno, Nicola, Ewers, Michael, Brendel, Matthias, Biel, Davina, Strandberg, Olof, Janelidze, Shorena, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Smith, Ruben, Stomrud, Erik, Ossenkoppele, Rik, Hansson, Oskar

“…For optimal design of anti-amyloid-β (Aβ) and anti-tau clinical trials, we need to better understand the pathophysiological cascade of Aβ- and tau-related…”
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Type 2 diabetes mellitus, brain atrophy, and cognitive decline by Moran, Chris, Wang, Wei, Callisaya, Michele, Aisen, Paul, Jagust, William, Trojanowki, John Q, Beckett, Laurel, Green, Robert C, Saykin, Andrew J, Montine, Tom, Gamst, Anthony, Gessert, Devon, Kornak, John, Alexander, Gene, DeCarli, Charles, Bandy, Dan, Koeppe, Robert A, Mathis, Chet, Cairns, Nigel J, Taylor-Reinwald, Lisa, Trojanowki, J.Q, Korecka, Magdalena, Neu, Scott, Foroud, Tatiana M, Potkin, Steven, Shen, Li, Frank, Richard, Kaye, Jeffrey, Dolen, Sara, Pawluczyk, Sonia, Spann, Bryan M, Brewer, James, Lord, Joanne L, Chowdhury, Munir, Bell, Karen L, Morris, John C, Leon, Sue, Schneider, Stacy, deToledo-Morrell, Leyla, Shah, Raj C, Albert, Marilyn, Onyike, Chiadi, Kielb, Stephanie, Rusinek, Henry, Doraiswamy, P Murali, Coleman, R Edward, Wolk, David, Jicha, Greg, Oakley, MaryAnn, Simpson, Donna M, Porsteinsson, Anton P, McAdams-Ortiz, Catherine, Womack, Kyle, Martin-Cook, Kristen, Lah, James J, Burns, Jeffrey M, Anderson, Heather S, Silverman, Daniel H.S, Graff-Radford, Neill R, Johnson, Heather, Farlow, Martin R, Hake, Ann Marie, Matthews, Brandy R, Herring, Scott, Carson, Richard E, MacAvoy, Martha G, Hosein, Chris, Caldwell, Curtis, Mudge, Benita, Rogers, John, Kerwin, Diana, Mesulam, Marek-Marsel, Taylor, Joy L, Tinklenberg, Jared, Sabbagh, Marwan, Kowall, Neil, Killiany, Ronald, Bwayo, Salome K, Lerner, Alan, Hudson, Leon, Ogrocki, Paula, Bartha, Dr Rob, Johnson, Sterling, Asthana, Sanjay, Scharre, Douglas W, Zimmerman, Earl A, Brown, Alice D, Pearlson, Godfrey D, Blank, Karen, Santulli, Robert B, Williamson, Jeff D, Ott, Brian R, Correia, Stephen, Rachinsky, Irina, Drost, Dick, Hernando, Raymundo, Sarrael, Antero, Shim, Hyungsub, Chaing, Gloria, Smith, Amanda

“…OBJECTIVETo study longitudinal relationships between type 2 diabetes mellitus (T2DM), cortical thickness, and cognitive function in older people with normal…”
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Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states by Mahjoub, Ines, Mahjoub, Mohamed Ali, Rekik, Islem

“…Accurate diagnosis of mild cognitive impairment (MCI) before conversion to Alzheimer’s disease (AD) is invaluable for patient treatment. Many works showed that…”
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KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease by Neitzel, Julia, Franzmeier, Nicolai, Rubinski, Anna, Dichgans, Martin, Brendel, Matthias, Malik, Rainer, Ewers, Michael

“…Klotho-VS heterozygosity (KL-VS het ) is associated with reduced risk of Alzheimer’s disease (AD). However, whether KL-VS het is associated with lower levels…”
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Tau‐Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease by McCollum, Lauren, Jack, Clifford R., Thomas, Ronald G., Walter, Sarah, Sather, Tamie, Donohue, Michael, Bernstein, Matthew, Borowski, Bret, Kantarci, Kejal, Ward, Chad, Koeppe, Robert A., Mathis, Chet, Cairns, Nigel J., Korecka, Magdalena, Figurski, Michal, Crawford, Karen, Snyder, Peter J., Molchan, Susan, Lind, Betty, Dolen, Sara, Spann, Bryan M., Vanderswag, Helen, Fleisher, Adam, Rountree, Susan, Dang, Mimi, Honig, Lawrence S., Leon, Sue, Mintun, Mark A., Schneider, Stacy, Clark, David, Brockington, John, Roberson, Erik, Albert, Marilyn, Kielb, Stephanie, Michel, Christina A., Leon, Mony J, De Santi, Susan, Wolk, David, Smith, Charles D., Jicha, Greg, Oates, Elizabeth, Conrad, Gary, Lopez, Oscar L., Oakley, MaryAnn, Goldstein, Bonnie S., Martin, Kim, Makino, Kelly M., Mulnard, Ruth A., Ortiz, Catherine Mc Adams, Womack, Kyle, Quiceno, Mary, Arrastia, Ramon Diaz, Weiner, Myron, DeVous, Michael, Cellar, Janet S., Bums, Jeffrey M., Anderson, Heather S., Woo, Ellen, Parfitt, Francine, Kendall, Tracy, Johnson, Heather, Hake, Ann Marie, Hunt, Cynthia, Carson, Richard E., MacAvoy, Martha G., Bergman, Howard, Stefanovic, Bojana, Feldman, Howard, Assaly, Michele, Kertesz, Andrew, Rogers, John, Trost, Dick, Wu, Chuang Kuo, Johnson, Keith A., Marshall, Gad, Taylor, Joy L., Lane, Barton, Rosen, Allison, Belden, Christine M., Kowall, Neil, Norbash, Alexan, Hudson, Leon, Olichney, John, Lee, T Y, Bartha, Rob, Johnson, Sterling, Asthana, Sanjay, Capote, Horacio, Williamson, Jeff D., Watkins, Franklin, Salloway, Stephen, Malloy, Paul, Rosen, Howard J., Miller, Bruce L., Mintzer, Jacobo, Bachman, David, Finger, Elizabether, Rogers, John, Kertesz, Andrew, Fargher, Kristin

“…Objective Tau neurofibrillary tangles (T) are the primary driver of downstream neurodegeneration (N) and subsequent cognitive impairment in Alzheimer's disease…”
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Hypertension accentuates reductions in CSF Aβ42 in elderly depressives: Biomarkers (non‐neuroimaging) / novel biomarkers by Pomara, Nunzio, Bruno, Davide, Reichert, Chelsea, Lee, Sang Han, Sarreal, Antero, Hernando, Raymundo, Ramos‐Cejudo, Jaime, Zetterberg, Henrik, Blennow, Kaj

“…Abstract Background Hypertension (HTN) is a well‐established risk factor for Alzheimer’s disease (AD). Observations from animal and human PET studies indicate…”
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Hypertension accentuates reductions in CSF Aβ42 in elderly depressives by Pomara, Nunzio, Bruno, Davide, Reichert, Chelsea, Lee, Sang Han, Sarreal, Antero, Hernando, Raymundo, Ramos‐Cejudo, Jaime, Zetterberg, Henrik, Blennow, Kaj

“…Background Hypertension (HTN) is a well‐established risk factor for Alzheimer’s disease (AD). Observations from animal and human PET studies indicate that HTN…”
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Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics by Varatharajah, Yogatheesan, Ramanan, Vijay K., Iyer, Ravishankar, Vemuri, Prashanthi

“…In the Alzheimer’s disease (AD) continuum, the prodromal state of mild cognitive impairment (MCI) precedes AD dementia and identifying MCI individuals at risk…”
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Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease by Hu, William T., Ozturk, Tugba, Kollhoff, Alexander, Wharton, Whitney, Christina Howell, J.

“…Neuroinflammation is associated with Alzheimer’s disease, but the application of cerebrospinal fluid measures of inflammatory proteins may be limited by…”
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Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification by Hett, Kilian, Ta, Vinh-Thong, Catheline, Gwenaëlle, Tourdias, Thomas, Manjón, José V., Coupé, Pierrick

“…Numerous studies have proposed biomarkers based on magnetic resonance imaging (MRI) to detect and predict the risk of evolution toward Alzheimer’s disease…”
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Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort by Oka, Takaki, Matsuzawa, Yuki, Tsuneyoshi, Momoka, Nakamura, Yoshitaka, Aoshima, Ken, Tsugawa, Hiroshi

“…Alzheimer's disease (AD) is a neurodegenerative disease that commonly causes dementia. Identifying biomarkers for the early detection of AD is an emerging…”
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Vitamin E in aging persons with Down syndrome: A randomized, placebo-controlled clinical trial by Sano, Mary, Aisen, Paul S, Andrews, Howard F, Tsai, Wei-Yann, Lai, Florence, Dalton, Arthur J

“…OBJECTIVE:To determine whether vitamin E would slow the progression of cognitive deterioration and dementia in aging persons with Down syndrome (DS). METHODS:A…”
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Author Correction: Predicting Alzheimer’s disease progression using multi-modal deep learning approach by Lee, Garam, Nho, Kwangsik, Kang, Byungkon, Sohn, Kyung-Ah, Kim, Dokyoon

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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