Search Results - "Hernandez, Silvia C."

Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesis by Li, Ruoshui, Chen, Bijun, Kubota, Akihiko, Hanna, Anis, Humeres, Claudio, Hernandez, Silvia C., Liu, Yang, Ma, Richard, Tuleta, Izabela, Huang, Shuaibo, Venugopal, Harikrishnan, Zhu, Fenglan, Su, Kai, Li, Jun, Zhang, Jinghang, Zheng, Deyou, Frangogiannis, Nikolaos G.

“…Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after…”
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Secreted Phosphoprotein 1 Expression in Endometrium and Placental Tissues of Hyperprolific Large White and Meishan Gilts by HERNANDEZ, Silvia C, HOGG, Charis O, BILLON, Yvon, SANCHEZ, Marie-Pierre, BIDANEL, Jean-Pierre, HALEY, Christopher S, ARCHIBALD, Alan L, ASHWORTH, Cheryl J

“…Increased litter size and within-litter uniformity in birth weight would improve pig reproductive efficiency. This study compared the location and gene and…”
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Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure by Humeres, Claudio, Shinde, Arti V, Hanna, Anis, Alex, Linda, Hernández, Silvia C, Li, Ruoshui, Chen, Bijun, Conway, Simon J, Frangogiannis, Nikolaos G

“…Repair of the infarcted heart requires TGF-β/Smad3 signaling in cardiac myofibroblasts. However, TGF-β-driven myofibroblast activation needs to be tightly…”
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A Systematic Review of Interventions for Hope/Hopelessness in Older Adults by Hernandez, Silvia C., Overholser, James C.

“…Objectives: Hope/hopelessness is an important determinant of health and death, and is a modifiable risk factor for older adults. The present review aimed to…”
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Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction by Ruiz-Villalba, Adrián, Romero, Juan P., Hernández, Silvia C., Vilas-Zornoza, Amaia, Fortelny, Nikolaus, Castro-Labrador, Laura, San Martin-Uriz, Patxi, Lorenzo-Vivas, Erika, García-Olloqui, Paula, Palacio, Marcel, Gavira, Juan José, Bastarrika, Gorka, Janssens, Stefan, Wu, Ming, Iglesias, Elena, Abizanda, Gloria, de Morentin, Xabier Martinez, Lasaga, Miren, Planell, Nuria, Bock, Christoph, Alignani, Diego, Medal, Gema, Prudovsky, Igor, Jin, Yong-Ri, Ryzhov, Sergey, Yin, Haifeng, Pelacho, Beatriz, Gomez-Cabrero, David, Lindner, Volkhard, Lara-Astiaso, David, Prósper, Felipe

“…BACKGROUND:Cardiac fibroblasts (CFs) have a central role in the ventricular remodeling process associated with different types of fibrosis. Recent studies have…”
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Cardiac Pericytes Acquire a Fibrogenic Phenotype and Contribute to Vascular Maturation After Myocardial Infarction by Alex, Linda, Tuleta, Izabela, Hernandez, Silvia C., Hanna, Anis, Venugopal, Harikrishnan, Astorkia, Maider, Humeres, Claudio, Kubota, Akihiko, Su, Kai, Zheng, Deyou, Frangogiannis, Nikolaos G.

“…Pericytes have been implicated in tissue repair, remodeling, and fibrosis. Although the mammalian heart contains abundant pericytes, their fate and involvement…”
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Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium by Chen, Bijun, Li, Ruoshui, Hernandez, Silvia C., Hanna, Anis, Su, Kai, Shinde, Arti V., Frangogiannis, Nikolaos G.

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The role of endogenous Smad7 in regulating macrophage phenotype following myocardial infarction by Li, Jun, Li, Ruoshui, Tuleta, Izabela, Hernandez, Silvia C., Humeres, Claudio, Hanna, Anis, Chen, Bijun, Frangogiannis, Nikolaos G.

“…Smad7 restrains TGF‐β responses, and has been suggested to exert both pro‐ and anti‐inflammatory actions that may involve effects on macrophages. Myocardial…”
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Macrophages in the infarcted heart acquire a fibrogenic phenotype, expressing matricellular proteins, but do not undergo fibroblast conversion by Li, Ruoshui, Hanna, Anis, Huang, Shuaibo, Hernandez, Silvia C., Tuleta, Izabela, Kubota, Akihiko, Humeres, Claudio, Chen, Bijun, Liu, Yang, Zheng, Deyou, Frangogiannis, Nikolaos G.

“…Although some studies have suggested that macrophages may secrete structural collagens, and convert to fibroblast-like cells, macrophage to fibroblast…”
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Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart by Humeres, Claudio, Shinde, Arti V, Tuleta, Izabela, Hernandez, Silvia C, Hanna, Anis, Huang, Shuaibo, Venugopal, Harikrishnan, Aguilan, Jennifer T, Conway, Simon J, Sidoli, Simone, Frangogiannis, Nikolaos G

“…Cardiac fibroblast activation contributes to adverse remodeling, fibrosis, and dysfunction in the pressure-overloaded heart. Although early fibroblast TGF-β…”
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CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells by Soochit, Widia, Sleutels, Frank, Stik, Gregoire, Bartkuhn, Marek, Basu, Sreya, Hernandez, Silvia C., Merzouk, Sarra, Vidal, Enrique, Boers, Ruben, Boers, Joachim, van der Reijden, Michael, Geverts, Bart, van Cappellen, Wiggert A., van den Hout, Mirjam, Ozgur, Zeliha, van IJcken, Wilfred F. J., Gribnau, Joost, Renkawitz, Rainer, Graf, Thomas, Houtsmuller, Adriaan, Grosveld, Frank, Stadhouders, Ralph, Galjart, Niels

“…The 11 zinc finger (ZF) protein CTCF regulates topologically associating domain formation and transcription through selective binding to thousands of genomic…”
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Suicide among older adults: Interactions among key risk factors by Hernandez, Silvia C, Overholser, James C, Philips, Kristie L, Lavacot, James, Stockmeier, Craig A

“…Objective The present study aimed to understand how key risk factors of older adult suicide interact to ultimately lead to death by suicide using data…”
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Secreted Phosphoprotein 1 Expression in Endometrium and Placental Tissues of Hyperprolific Large White and Meishan Gilts1 by Hernandez, Silvia C, Hogg, Charis O, Billon, Yvon, Sanchez, Marie-Pierre, Bidanel, Jean-Pierre, Haley, Christopher S, Archibald, Alan L, Ashworth, Cheryl J

“…Increased litter size and within-litter uniformity in birth weight would improve pig reproductive efficiency. This study compared the location and gene and…”
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Abstract P2052: Fibroblast-specific TGF-b Signaling Protects The Infarcted Myocardium From Adipose Tissue Infiltration by Tuleta, Izabela, Venugopal, Harikrishnan, Humeres, Claudio, Hernandez, Silvia C, Kubota, Akihiko, Hanna, Anis, Frangogiannis, Nikolaos G

“…Abstract only Background and Objectives: Repair of the infarcted heart requires timely phenotypic transitions of fibroblasts, the central effector cells…”
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Abstract P2051: Fibroblast-specific TGF-b Signaling Promotes Interstitial Fibrosis, Cardiomyocyte Hypertrophy And Cardiac Dysfunction In The Diabetic Heart Through Smad3 Activation by Tuleta, Izabela, Alex, Linda, Venugopal, Harikrishnan, Humeres, Claudio, Hernandez, Silvia C, Kubota, Akihiko, Hanna, Anis, Frangogiannis, Nikolaos G

“…Abstract only Objectives: Patients with diabetes exhibit a high prevalence of HFpEF associated with interstitial fibrosis and cardiomyocyte hypertrophy…”
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Abstract P2110: Fibroblast-specific Smad6 Restrains Adverse Remodeling And Dysfunction Following Myocardial Infarction by Venugopal, Harikrishnan, Tuleta, Izabela, Hanna, Anis, Kubota, Akihiko, Hernandez, Silvia C, Humeres, Claudio, Zhu, Fenglan, Frangogiannis, Nikolaos G

“…Abstract only Signaling induced by the Transforming Growth Factor (TGF)-β superfamily members in fibroblasts plays a central role in repair and remodeling…”
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Cardiac pericytes acquire a fibrogenic phenotype and contribute to vascular maturation following myocardial infarction by Alex, Linda, Tuleta, Izabela, Hernandez, Silvia C, Hanna, Anis, Venugopal, Harikrishnan, Astorkia, Maider, Humeres, Claudio, Kubota, Akihiko, Su, Kai, Zheng, Deyou, Frangogiannis, Nikolaos G

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Smad7 effects on TGF-[beta] and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure by Humeres, Claudio, Shinde, Arti V, Hanna, Anis, Alex, Linda, Hernandez, Silvia C, Li, Ruoshui, Chen, Bijun, Conway, Simon J, Frangogiannis, Nikolaos G

“…Repair of the infarcted heart requires TGF-[beta]/Smad3 signaling in cardiac myofibroblasts. However, TGF-[beta]-driven myofibroblast activation needs to be…”
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Suicidal Ideation Across Adulthood: Applying Erikson's Theory of Psychosocial Development by Hernandez, Silvia C

“…Objective: The present study aimed to explore the relationships between Erik Erikson’s adult stages of psychosocial development (intimacy/isolation,…”
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Clinical Recommendations for Addressing Impasses in Long-Term Psychotherapy by Hernandez, Silvia, Overholser, James, McCarthy, Kevin

“…Many clients benefit from psychotherapy sessions that extend across months or years. However, there is a risk for therapeutic impasse in long-term…”
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