Search Results - "Hernandez, Jose Antonio G."

The Role of Class II Human Leukocyte Antigens (cII-HLAs) in Determining the Immunogenic Potential of Therapeutic Factor VIII Proteins in Hemophilia Patients: The “Gate Keeper” Hypothesis by Diego, Vincent P., Luu, Bernadette W., Hofmann, Marco, Almeida, Marcio A., Hernandez, Jose Antonio G., Peralta, Juan, Curran, Joanne, Powell, Jerry S., Rajalingam, Raja, Dinh, Long V., Williams-Blangero, Sarah, Escobar, Miguel A, Maraskovsky, Eugene, Blangero, John, Howard, Tom E.

“…The development of neutralizing antibodies-termed “inhibitors”-to infused therapeutic (t) factor VIII proteins (tFVIIIs) is the most serious obstacle to…”
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Characterization of the HLA-Class-II (HLAcII)/Therapeutic Factor VIII (FVIII)-Derived Peptidome By FVIII Domain and HLAcII Isomer by Almeida, Marcio, Diego, Vincent P., Luu, Bernadette W., Hofmann, Marco, Hernandez, Jose Antonio G., Peralta, Juan, Curran, Joanne, Escobar, Miguel A, Raja, Rajalingam, Dinh, LV, Powell, Jerry S., Williams-Blangero, Sarah, Blangero, John, Maraskovsky, Eugene, Howard, Tom

“…Background: Hemophilia A (HA) is caused by F8 mutations and resultant plasma deficiencies in FVIII activity. While bleeding can be arrested by infusing…”
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