Search Results - "Hernandez, Francisco J."

Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects by López-Hernández, Francisco J, López-Novoa, Jose M

“…Transforming growth factor beta (TGF-β) has been recognized as an important mediator in the genesis of chronic kidney diseases (CKD), which are characterized…”
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Pathophysiology of Acute Kidney Frailty by Sancho-Martínez, Sandra M., López-Hernández, Francisco J.

“…Acute kidney frailty is a premorbid condition of diminished renal functional reserve that predisposes to acute kidney injury; this condition results from…”
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An integrative view on the role of TGF-β in the progressive tubular deletion associated with chronic kidney disease by García-Sánchez, Omar, López-Hernández, Francisco J., López-Novoa, José M.

“…Transforming growth factor-β (TGF-β) is a cytokine known to participate in several processes related to the development of chronic kidney disease (CKD),…”
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Renal sympathetic activity: A key modulator of pressure natriuresis in hypertension by Díaz-Morales, Noelia, Baranda-Alonso, Eva M., Martínez-Salgado, Carlos, López-Hernández, Francisco J.

“…[Display omitted] Hypertension is a complex disorder ensuing necessarily from alterations in the pressure-natriuresis relationship, the main determinant of…”
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Higher response to lenalidomide in relapsed/refractory diffuse large B‐cell lymphoma in nongerminal center B‐cell–like than in germinal center B‐cell–like phenotype by Hernandez‐Ilizaliturri, Francisco J., Deeb, George, Zinzani, Pier L., Pileri, Stefano A., Malik, Farhana, Macon, William R., Goy, Andre, Witzig, Thomas E., Czuczman, Myron S.

“…BACKGROUND: There is a need to develop novel therapies for relapsed/refractory diffuse large B‐cell lymphoma (DLBCL) and to identify biomarkers predictive for…”
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Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats by Blanco-Gozalo, Víctor, Quiros, Yaremi, Vicente-Vicente, Laura, Casanova, Alfredo G., Sancho-Martínez, Sandra M., López-Hernández, Francisco J.

“…Nephrotoxicity, including electrolytic disorders and acute kidney injury (AKI), limits the clinical dosage and utility of platinated antineoplastics such as…”
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An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin by Quiros, Yaremi, Vicente-Vicente, Laura, Morales, Ana I, López-Novoa, José M, López-Hernández, Francisco J

“…Gentamicin is an aminoglycoside antibiotic widely used against infections by Gram-negative microorganisms. Nephrotoxicity is the main limitation to its…”
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Determining risk factors for triple whammy acute kidney injury by Leete, Jessica, Wang, Carolyn, López-Hernández, Francisco J., Layton, Anita T.

“…Concurrent use of a diuretic, a renin-angiotensin system (RAS) inhibitor, and a non-steroidal anti-inflammatory drug (NSAID) significantly increases the risk…”
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Textural characteristics and facies of sand‐rich contourite depositional systems by Brackenridge, Rachel E., Stow, Dorrik A. V., Hernández‐Molina, Francisco J., Jones, Claudia, Mena, Anxo, Alejo, Irene, Ducassou, Emmanuelle, Llave, Estefanía, Ercilla, Gemma, Nombela, Miguel Angel, Perez‐Arlucea, Marta, Frances, Gillermo, Marzo, Mariano

“…This work presents a detailed study of CONTOURIBER and Integrated Ocean Drilling Program 339 sediment data targeting sand‐rich contourites in the Eastern Gulf…”
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Subcellular targets of cisplatin cytotoxicity: an integrated view by Sancho-Martínez, Sandra M, Prieto-García, Laura, Prieto, Marta, López-Novoa, José M, López-Hernández, Francisco J

“…Cisplatin is a chemotherapeutic drug widely used against a variety of cancers. Its clinical utility is severely limited by its toxicity, which mainly affects,…”
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Transgenerational Tolerance to Salt and Osmotic Stresses Induced by Plant Virus Infection by Hernández-Walias, Francisco J, García, Marina, Moreno, Marina, Giannoukos, Ioannis, González, Natalia, Sanz-García, Eugenio, Necira, Khouloud, Canto, Tomás, Tenllado, Francisco

“…Following pathogen infection, plants have developed diverse mechanisms that direct their immune systems towards more robust induction of defense responses…”
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Combined use of GM2AP and TCP1-eta urinary levels predicts recovery from intrinsic acute kidney injury by Blanco-Gozalo, Víctor, Casanova, Alfredo G., Sancho-Martínez, Sandra M., Prieto, Marta, Quiros, Yaremi, Morales, Ana I., Martínez-Salgado, Carlos, Agüeros-Blanco, Consuelo, Benito-Hernández, Adalberto, Ramos-Barron, María A., Gómez-Alamillo, Carlos, Arias, Manuel, López-Hernández, Francisco J.

“…Deficient recovery from acute kidney injury (AKI) has immediate and long-term health, clinical and economic consequences. Pre-emptive recovery estimation may…”
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Acquirement of Rituximab Resistance in Lymphoma Cell Lines Is Associated with Both Global CD20 Gene and Protein Down-Regulation Regulated at the Pretranscriptional and Posttranscriptional Levels by CZUCZMAN, Myron S, OLEJNICZAK, Scott, GOWDA, Aruna, KOTOWSKI, Adam, BINDER, Arvinder, KAUR, Harman, KNIGHT, Joy, STAROSTIK, Petr, DEANS, Julie, HERNANDEZ-LLIZALITURRI, Francisco J

“…Acquirement of resistance to rituximab has been observed in lymphoma patients. To define mechanisms associated with rituximab resistance, we developed various…”
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Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody by Goldenberg, David M., Rossi, Edmund A., Stein, Rhona, Cardillo, Thomas M., Czuczman, Myron S., Hernandez-Ilizaliturri, Francisco J., Hansen, Hans J., Chang, Chien-Hsing

“…Veltuzumab is a humanized anti-CD20 monoclonal antibody with complementarity-determining regions (CDRs) identical to rituximab, except for one residue at the…”
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Bohr–Fourier Series on Solenoids via its Transversal Variation by Cruz-López, Manuel, López-Hernández, Francisco J.

“…The Bohr–Fourier series development on one-dimensional solenoids is described using invariant functions and extending Bohr’s theory through the study of…”
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Estrogen receptor α and β are involved in the activation of lordosis behavior in estradiol-primed rats by Domínguez-Ordóñez, Raymundo, García-Juárez, Marcos, Lima-Hernández, Francisco J., Gómora-Arrati, Porfirio, Blaustein, Jeffrey D., Etgen, Anne M., González-Flores, Oscar

“…The present study was designed to assess the participation of estrogen receptors alpha (ERα) and beta (ERβ) in the short-term facilitation of lordosis behavior…”
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Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study by Torka, Pallawi, Akhtar, Othman S., Reddy, Nishitha M., Baysal, Bora E., Kader, Angela, Groman, Adrienne, Nichols, Jenna, Mavis, Cory, Tario, Joseph D., Block, AnneMarie W., Sait, Sheila N. J., Ghione, Paola, Sundaram, Suchitra, Przespolewski, Eugene R., Mohr, Alice, Lund, Ian, Kostrewa, Jessica, McWhite, Kenneth, DeMarco, Joseph, Johnson, Michael, Darrall, Andrea, Thomas‐Talley, Rosh‐Neke, Wallace, Paul K., Neppalli, Vishala, Hutson, Alan, Hernandez‐Ilizaliturri, Francisco J.

“…Background Ofatumumab is a humanized type 1 anti‐CD20 monoclonal antibody. Preclinical studies show improved complement‐mediated cytotoxicity (CMC) compared to…”
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Urinary TCP1-eta: A Cortical Damage Marker for the Pathophysiological Diagnosis and Prognosis of Acute Kidney Injury by Sancho-Martínez, Sandra M, Sánchez-Juanes, Fernando, Blanco-Gozalo, Víctor, Fontecha-Barriuso, Miguel, Prieto-García, Laura, Fuentes-Calvo, Isabel, González-Buitrago, José M, Morales, Ana I, Martínez-Salgado, Carlos, Ramos-Barron, María A, Gómez-Alamillo, Carlos, Arias, Manuel, López-Novoa, José M, López-Hernández, Francisco J

“…Abstract Acute kidney injury (AKI) is a serious syndrome with increasing incidence and health consequences, and high mortality rate among critically ill…”
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A systematic meta-analysis on the efficacy of pre-clinically tested nephroprotectants at preventing aminoglycoside nephrotoxicity by Vicente-Vicente, Laura, Casanova, Alfredo G, Hernández-Sánchez, María Teresa, Pescador, Moisés, López-Hernández, Francisco J, Morales, Ana Isabel

“…Abstract Nephrotoxicity limits the use of aminoglycoside antibiotics. Kidney damage is produced mainly in the renal tubule due to an inflammatory and oxidative…”
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External validation and comparison of the CardShock and IABP-SHOCK II risk scores in real-world cardiogenic shock patients by Rivas-Lasarte, Mercedes, Sans-Roselló, Jordi, Collado-Lledó, Elena, González-Fernández, Víctor, Noriega, Francisco J, Hernández-Pérez, Francisco J, Fernández-Martínez, Juan, Ariza, Albert, Lidón, Rosa-Maria, Viana-Tejedor, Ana, Segovia-Cubero, Javier, Harjola, Veli-Pekka, Lassus, Johan, Thiele, Holger, Sionis, Alessandro

“…Mortality from cardiogenic shock remains high and early recognition and risk stratification are mandatory for optimal patient allocation and to guide treatment…”
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