Search Results - "Hernaez, Maria Luisa"
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1
Quantitative Proteome and Acidic Subproteome Profiling of Candida albicans Yeast-to-Hypha Transition
Published in Journal of proteome research (04-02-2011)“…Candida albicans yeast-to-hypha morphological transition is involved in the virulence strategy of this opportunistic fungal pathogen. Changes in relative…”
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2
In Vitro Transcription/Translation System: A Versatile Tool in the Search for Missing Proteins
Published in Journal of proteome research (04-09-2015)“…Approximately 18% of all human genes purported to encode proteins have not been directly evidenced at the protein level, according to the validation criteria…”
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3
Statistical Evaluation of Metaproteomics and 16S rRNA Amplicon Sequencing Techniques for Study of Gut Microbiota Establishment in Infants with Cystic Fibrosis
Published in Microbiology spectrum (21-12-2022)“…Newborn screening for cystic fibrosis (CF) can identify affected but asymptomatic infants. The selection of omic technique for gut microbiota study is crucial…”
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4
Candida albicans Hyphal Extracellular Vesicles Are Different from Yeast Ones, Carrying an Active Proteasome Complex and Showing a Different Role in Host Immune Response
Published in Microbiology spectrum (01-06-2022)“…Candida albicans is the principal causative agent of lethal fungal infections, predominantly in immunocompromised hosts. Extracellular vesicles (EVs) have been…”
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5
Dual Regulation of the Mitotic Exit Network (MEN) by PP2A-Cdc55 Phosphatase: e1003966
Published in PLoS genetics (01-12-2013)“…Exit from mitosis in budding yeast is triggered by activation of the key mitotic phosphatase Cdc14. At anaphase onset, the protease separase and Zds1 promote…”
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6
Combined Proteomic Approaches for the Identification of Specific Amino Acid Residues Modified by 4-Hydroxy-2-Nonenal under Physiological Conditions
Published in Journal of proteome research (05-11-2010)“…Proteins modified by 4-hydroxy-2-nonenal (HNE) are cellular markers of oxidative stress in health and disease. HNE is generated by free radical chain reactions…”
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7
Comparative tachyzoite proteome analyses among six Neospora caninum isolates with different virulence
Published in International journal for parasitology (01-05-2020)“…[Display omitted] •High and low virulence Neospora caninum isolates showed differences in their proteomes.•Comparative analysis revealed a subset of secreted…”
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8
General Statistical Framework for Quantitative Proteomics by Stable Isotope Labeling
Published in Journal of proteome research (07-03-2014)“…The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures…”
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9
Phosphoproteomic Analysis of Protein Kinase C Signaling in Saccharomyces cerevisiae Reveals Slt2 Mitogen-activated Protein Kinase (MAPK)-dependent Phosphorylation of Eisosome Core Components
Published in Molecular & cellular proteomics (01-03-2013)“…The cell wall integrity (CWI) pathway of the model organism Saccharomyces cerevisiae has been thoroughly studied as a paradigm of the mitogen-activated protein…”
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10
Unravelling the Role of Candida albicans Prn1 in the Oxidative Stress Response through a Proteomics Approach
Published in Antioxidants (26-04-2024)“…Prn1 is a protein with an unknown function similar to mammalian Pirin. It also has orthologues in other pathogenic fungi, but not in . Prn1 highly increases…”
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11
Distinct Human Gut Microbial Taxonomic Signatures Uncovered With Different Sample Processing and Microbial Cell Disruption Methods for Metaproteomic Analysis
Published in Frontiers in microbiology (05-07-2021)“…The use of metaproteomics for studying the human gut microbiota can shed light on the taxonomic profile and the functional role of the microbial community…”
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12
Enrichment of ATP Binding Proteins Unveils Proteomic Alterations in Human Macrophage Cell Death, Inflammatory Response, and Protein Synthesis after Interaction with Candida albicans
Published in Journal of proteome research (03-05-2019)“…Macrophages are involved in the primary human response to Candida albicans. After pathogen recognition, signaling pathways are activated, leading to the…”
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13
Identification of the Missing Protein Hyaluronan Synthase 1 in Human Mesenchymal Stem Cells Derived from Adipose Tissue or Umbilical Cord
Published in Journal of proteome research (07-12-2018)“…Currently, 14% of the human proteome is made up of proteins whose existence is not confirmed by mass spectrometry. We performed a proteomic profiling of human…”
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14
Quantitative differential proteomics of yeast extracellular matrix: there is more to it than meets the eye
Published in BMC microbiology (25-11-2015)“…Saccharomyces cerevisiae multicellular communities are sustained by a scaffolding extracellular matrix, which provides spatial organization, and nutrient and…”
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15
Dual Regulation of the mitotic exit network (MEN) by PP2A-Cdc55 phosphatase
Published in PLoS genetics (01-12-2013)“…Exit from mitosis in budding yeast is triggered by activation of the key mitotic phosphatase Cdc14. At anaphase onset, the protease separase and Zds1 promote…”
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Journal Article -
16
Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach
Published in Journal of proteomics (07-05-2010)“…We have set up a fast and easy methodology to identify cell-surface proteins in live yeasts. A non-gel proteomic approach was based on a short period of…”
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17
Gel and gel-free proteomics to identify Saccharomyces cerevisiae cell surface proteins
Published in Journal of proteomics (18-04-2010)“…The study of Saccharomyces cerevisiae cell surface proteins was performed because of their important role in cell wall biogenesis and in the physiology of the…”
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Journal Article Conference Proceeding -
18
Surfing Transcriptomic Landscapes. A Step beyond the Annotation of Chromosome 16 Proteome
Published in Journal of proteome research (03-01-2014)“…The Spanish team of the Human Proteome Project (SpHPP) marked the annotation of Chr16 and data analysis as one of its priorities. Precise annotation of…”
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19
Inter-laboratory evaluation of instrument platforms and experimental workflows for quantitative accuracy and reproducibility assessment
Published in EuPA open proteomics (01-09-2015)“…[Display omitted] •Reproducibility of MRM with SIS peptides for plasma protein quantitation was studied.•This was an international study featuring 16…”
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20
Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host–pathogen interaction
Published in Journal of proteomics (08-09-2015)“…The ability to switch from yeast to hyphal growth is essential for virulence in Candida albicans. The cell surface is the initial point of contact between the…”
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