Search Results - "Hernández‐Guillamon, Mar"

MMP-9-Positive Neutrophil Infiltration Is Associated to Blood-Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke by ROSELL, Anna, CUADRADO, Eloy, ORTEGA-AZNAR, Arantxa, HERNANDEZ-GUILLAMON, Mar, LO, Eng H, MONTANER, Joan

“…An abnormal expression of some matrix metalloproteinases (MMPs) is related with hemorrhagic transformation events after stroke. Our aim was to investigate…”
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Therapeutic effect of human ApoA‐I‐Milano variant in aged transgenic mouse model of Alzheimer's disease by Solé, Montse, Marazuela, Paula, Castellote, Laura, Bonaterra‐Pastra, Anna, Giménez‐Llort, Lydia, Hernández‐Guillamon, Mar

“…Background and Purpose Therapies based on apolipoprotein A‐I (ApoA‐I), classically tested for cardiovascular diseases, were recently proposed for Alzheimer's…”
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Impact of Cerebral Amyloid Angiopathy in Two Transgenic Mouse Models of Cerebral β-Amyloidosis: A Neuropathological Study by Marazuela, Paula, Paez-Montserrat, Berta, Bonaterra-Pastra, Anna, Solé, Montse, Hernández-Guillamon, Mar

“…The pathological accumulation of parenchymal and vascular amyloid-beta (Aβ) are the main hallmarks of Alzheimer's disease (AD) and Cerebral Amyloid Angiopathy…”
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Plasmatic retinol‐binding protein 4 and glial fibrillary acidic protein as biomarkers to differentiate ischemic stroke and intracerebral hemorrhage by Llombart, Víctor, García‐Berrocoso, Teresa, Bustamante, Alejandro, Giralt, Dolors, Rodriguez‐Luna, David, Muchada, Marian, Penalba, Anna, Boada, Cristina, Hernández‐Guillamon, Mar, Montaner, Joan

“…A rapid differentiation of acute ischemic stroke and intracerebral hemorrhage (ICH) is essential for an adequate treatment and to promote a better outcome. Our…”
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New candidate blood biomarkers potentially associated with white matter hyperintensities progression by Jiménez-Balado, Joan, Pizarro, Jesús, Riba-Llena, Iolanda, Penalba, Anna, Faura, Júlia, Palà, Elena, Montaner, Joan, Hernández-Guillamon, Mar, Delgado, Pilar

“…We aimed to discover blood biomarkers associated with longitudinal changes in white matter hyperintensities (WMH). This study was divided into a discovery…”
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Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease by Camacho, Jessica, Rábano, Alberto, Marazuela, Paula, Bonaterra‐Pastra, Anna, Serna, Garazi, Moliné, Teresa, Ramón y Cajal, Santiago, Martínez‐Sáez, Elena, Hernández‐Guillamon, Mar

“…Genome‐wide association studies have described several genes as genetic susceptibility loci for Alzheimer's disease (AD). Among them, CD2AP encodes…”
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Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice by Rosell, Anna, Morancho, Anna, Navarro-Sobrino, Miriam, Martínez-Saez, Elena, Hernández-Guillamon, Mar, Lope-Piedrafita, Silvia, Barceló, Verónica, Borrás, Francesc, Penalba, Anna, García-Bonilla, Lidia, Montaner, Joan

“…Cell therapy with endothelial progenitor cells (EPCs) has emerged as a promising strategy to regenerate the brain after stroke. Here, we aimed to investigate…”
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Evidence for the efficacy of statins in animal stroke models: a meta-analysis by García-Bonilla, Lidia, Campos, Mireia, Giralt, Dolors, Salat, David, Chacón, Pilar, Hernández-Guillamon, Mar, Rosell, Anna, Montaner, Joan

“…J. Neurochem. (2012) 122, 233–243. Protective effects of statins have been well documented for stroke therapy. Here, we used a systematic review and…”
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Apolipoprotein J protects cardiomyocytes from lipid-mediated inflammation and cytotoxicity induced by the epicardial adipose tissue of diabetic patients by Puig, Núria, Rives, José, Gil-Millan, Pedro, Miñambres, Inka, Ginel, Antonino, Tauron, Manel, Bonaterra-Pastra, Anna, Hernández-Guillamon, Mar, Pérez, Antonio, Sánchez-Quesada, José Luís, Benitez, Sonia

“…Diabetic patients present increased volume and functional alterations in epicardial adipose tissue (EAT). We aimed to analyze EAT from type 2 diabetic patients…”
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Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis by Fernández-de-Retana, Sofía, Cano-Sarabia, Mary, Marazuela, Paula, Sánchez-Quesada, Jose Luis, Garcia-Leon, Annabel, Montañola, Alex, Montaner, Joan, Maspoch, Daniel, Hernández-Guillamon, Mar

“…Cerebral β-amyloidosis is a major feature of Alzheimer’s disease (AD), characterized by the accumulation of β-amyloid protein (Aβ) in the brain. Several…”
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Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release by Cuadrado, Eloy, Ortega, Laura, Hernández‐Guillamon, Mar, Penalba, Anna, Fernández‐Cadenas, Israel, Rosell, Anna, Montaner, Joan

“…Recombinant tissue plasminogen activator (t‐PA), the only approved stroke treatment, is used for clot lysis within the occluded brain artery. Unfortunately,…”
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The presence of circulating human apolipoprotein J reduces the occurrence of cerebral microbleeds in a transgenic mouse model with cerebral amyloid angiopathy by Bonaterra-Pastra, Anna, Solé, Montse, Lope-Piedrafita, Silvia, Lucas-Parra, Maria, Castellote, Laura, Marazuela, Paula, Pancorbo, Olalla, Rodríguez-Luna, David, Hernández-Guillamon, Mar

“…Cerebral amyloid angiopathy (CAA) is characterized by amyloid-β (Aβ) deposition in cerebral vessels, leading to lobar cerebral microbleeds (CMB) and…”
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Circulating TIMP-1 is associated with hematoma volume in patients with spontaneous intracranial hemorrhage by Navarro-Oviedo, Manuel, Muñoz-Arrondo, Roberto, Zandio, Beatriz, Marta-Enguita, Juan, Bonaterra-Pastra, Anna, Rodríguez, Jose Antonio, Roncal, Carmen, Páramo, Jose A., Toledo, Estefania, Montaner, Joan, Hernández-Guillamon, Mar, Orbe, Josune

“…Matrix metalloproteinases (MMPs) are proteolytic zinc-endopeptidases regulated by tissue Inhibitors of matrix metalloproteinases (TIMPs). We evaluated the…”
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Cerebral ischaemia and matrix metalloproteinase‐9 modulate the angiogenic function of early and late outgrowth endothelial progenitor cells by Morancho, Anna, Hernández‐Guillamon, Mar, Boada, Cristina, Barceló, Verónica, Giralt, Dolors, Ortega, Laura, Montaner, Joan, Rosell, Anna

“…The enhancement of endogenous angiogenesis after stroke will be critical in neurorepair therapies where endothelial progenitor cells (EPCs) might be key…”
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Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 mice by de Retana, Sofía Fernández, Marazuela, Paula, Solé, Montse, Colell, Guillem, Bonaterra, Anna, Sánchez-Quesada, Jose Luis, Montaner, Joan, Maspoch, Daniel, Cano-Sarabia, Mary, Hernández-Guillamon, Mar

“…ApoJ/clusterin is a multifunctional protein highly expressed in the brain. The implication of ApoJ in β-amyloid (Aβ) fibrillization and clearance in the…”
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Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy by Camacho, Jessica, Moliné, Teresa, Bonaterra-Pastra, Anna, Ramón Y Cajal, Santiago, Martínez-Sáez, Elena, Hernández-Guillamon, Mar

“…Cerebral amyloid angiopathy (CAA) is a common cause of lobar intracerebral hemorrhage (ICH) in elderly individuals and it is the result of the cerebrovascular…”
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Cerebral Amyloid Angiopathy-Related Atraumatic Convexal Subarachnoid Hemorrhage: An ARIA before the Tsunami by Martínez-Lizana, Eva, Carmona-Iragui, María, Alcolea, Daniel, Gómez-Choco, Manuel, Vilaplana, Eduard, Sánchez-Saudinós, María B, Clarimón, Jordi, Hernández-Guillamon, Mar, Munuera, Josep, Gelpi, Ellen, Gómez-Anson, Beatriz, de Juan-Delago, Manel, Delgado-Mederos, Raquel, Montaner, Joan, Ois, Angel, Amaro, Sergi, Blesa, Rafael, Martí-Fàbregas, Joan, Lleó, Alberto, Fortea, Juan

“…Atraumatic convexal subarachnoid hemorrhage (cSAH) in elderly patients is a rare entity that has been associated with cerebral amyloid angiopathy (CAA) and…”
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Association of candidate genetic variants and circulating levels of ApoE/ApoJ with common neuroimaging features of cerebral amyloid angiopathy by Bonaterra-Pastra, Anna, Benítez, Sònia, Pancorbo, Olalla, Rodríguez-Luna, David, Vert, Carla, Rovira, Alex, Freijo, M Mar, Tur, Silvia, Martínez-Zabaleta, Maite, Cardona Portela, Pere, Vera, Rocío, Lebrato-Hernández, Lucia, Arenillas, Juan F, Pérez-Sánchez, Soledad, Domínguez-Mayoral, Ana, Fàbregas, Joan Martí, Mauri, Gerard, Montaner, Joan, Sánchez-Quesada, Jose Luis, Hernández-Guillamon, Mar

“…Cerebral amyloid angiopathy (CAA) is characterized by the accumulation of amyloid-β (Aβ) in brain vessels and is a main cause of lobar intracerebral hemorrhage…”
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Brain proteomics identifies potential simvastatin targets in acute phase of stroke in a rat embolic model by Campos‐Martorell, Mireia, Salvador, Nelida, Monge, Marta, Canals, Francesc, García‐Bonilla, Lidia, Hernández‐Guillamon, Mar, Ayuso, María Irene, Chacón, Pilar, Rosell, Anna, Alcazar, Alberto, Montaner, Joan

“…Finding an efficient neuroprotectant is of urgent need in the field of stroke research. The goal of this study was to test the effect of acute simvastatin…”
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MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy by Marazuela, Paula, Solé, Montse, Bonaterra-Pastra, Anna, Pizarro, Jesús, Camacho, Jessica, Martínez-Sáez, Elena, Kuiperij, H Bea, Verbeek, Marcel M, de Kort, Anna M, Schreuder, Floris H B M, Klijn, Catharina J M, Castillo-Ribelles, Laura, Pancorbo, Olalla, Rodríguez-Luna, David, Pujadas, Francesc, Delgado, Pilar, Hernández-Guillamon, Mar

“…Brain accumulation of amyloid-beta (Aβ) is a crucial feature in Alzheimer´s disease (AD) and cerebral amyloid angiopathy (CAA), although the pathophysiological…”
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